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Open-Access Journal
Editorial
Genome-based nutrition: An intervention strategy for the prevention and treatment of obesity and nonalcoholic steatohepatitis 
Sonia Roman, Claudia Ojeda-Granados, Omar Ramos-Lopez, Arturo Panduro 
World J Gastroenterol 21(12):3449-3461. Published online Mar 28, 2015. doi: 10.3748/wjg.v21.i12.3449
Review
Management of hepatocellular carcinoma with portal vein thrombosis 
Matthew Quirk, Yun Hwan Kim, Sammy Saab, Edward Wolfgang Lee 
World J Gastroenterol 21(12):3462-3471. Published online Mar 28, 2015. doi: 10.3748/wjg.v21.i12.3462
Lessons from rare tumors: Hepatic lymphoepithelioma-like carcinomas 
Antonio Solinas, Diego F Calvisi 
World J Gastroenterol 21(12):3472-3479. Published online Mar 28, 2015. doi: 10.3748/wjg.v21.i12.3472
Hepatitis C virus-specific cytotoxic T cell response restoration after treatment-induced hepatitis C virus control 
Juan-Ramón Larrubia, Elia Moreno-Cubero, Joaquín Miquel, Eduardo Sanz-de-Villalobos 
World J Gastroenterol 21(12):3480-3491. Published online Mar 28, 2015. doi: 10.3748/wjg.v21.i12.3480
Long-chain acyl-CoA synthetase in fatty acid metabolism involved in liver and other diseases: An update 
Sheng Yan, Xue-Feng Yang, Hao-Lei Liu, Nian Fu, Yan Ouyang, Kai Qing 
World J Gastroenterol 21(12):3492-3498. Published online Mar 28, 2015. doi: 10.3748/wjg.v21.i12.3492
Basic Study
Degradation of intestinal mRNA: A matter of treatment 
Sabine Heumüller-Klug, Carsten Sticht, Karin Kaiser, Elvira Wink, Cornelia Hagl, Lucas Wessel, Karl-Herbert Schäfer 
World J Gastroenterol 21(12):3499-3508. Published online Mar 28, 2015. doi: 10.3748/wjg.v21.i12.3499
Effect of entacapone on colon motility and ion transport in a rat model of Parkinson’s disease 
Li-Sheng Li, Chen-Zhe Liu, Jing-Dong Xu, Li-Fei Zheng, Xiao-Yan Feng, Yue Zhang, Jin-Xia Zhu 
World J Gastroenterol 21(12):3509-3518. Published online Mar 28, 2015. doi: 10.3748/wjg.v21.i12.3509
Primary analysis and screening of microRNAs in gastric cancer side population cells 
Hai-Hong Zhang, Guo-Li Gu, Xiang-Yang Zhang, Feng-Zhi Li, Li Ding, Qin Fan, Ran Wu, Wei Shi, Xin-Yan Wang, Lin Chen, Xue-Ming Wei, Xiao-Ying Yuan 
World J Gastroenterol 21(12):3519-3526. Published online Mar 28, 2015. doi: 10.3748/wjg.v21.i12.3519
High persistence rate of hepatitis B virus in a hydrodynamic injection-based transfection model in C3H/HeN mice 
Xiu-Hua Peng, Xiao-Nan Ren, Li-Xiang Chen, Bi-Sheng Shi, Chun-Hua Xu, Zhong Fang, Xue Liu, Jie-Liang Chen, Xiao-Nan Zhang, Yun-Wen Hu, Xiao-Hui Zhou 
World J Gastroenterol 21(12):3527-3536. Published online Mar 28, 2015. doi: 10.3748/wjg.v21.i12.3527
Therapeutic effect of Qingyi decoction in severe acute pancreatitis-induced intestinal barrier injury 
Jing-Wen Zhang, Gui-Xin Zhang, Hai-Long Chen, Ge-Liang Liu, Lawrence Owusu, Yu-Xi Wang, Guan-Yu Wang, Cai-Ming Xu 
World J Gastroenterol 21(12):3537-3546. Published online Mar 28, 2015. doi: 10.3748/wjg.v21.i12.3537
Case Control Study
Surgical outcomes of Korean ulcerative colitis patients with and without colitis-associated cancer 
Yong Sik Yoon, Yong Beom Cho, Kyu Joo Park, Seung Hyuk Baik, Sang Nam Yoon, Seung-Bum Ryoo, Kil Yeon Lee, Hungdai Kim, Ryung-Ah Lee, Chang Sik Yu; IBD Study Group, Korean Society of Coloproctology 
World J Gastroenterol 21(12):3547-3553. Published online Mar 28, 2015. doi: 10.3748/wjg.v21.i12.3547
Primary biliary cirrhosis-associated hepatocellular carcinoma in Chinese patients: Incidence and risk factors 
Xue-Xiu Zhang, Li-Feng Wang, Lei Jin, Yuan-Yuan Li, Shu-Li Hao, Yan-Chao Shi, Qing-Lei Zeng, Zhi-Wei Li, Zheng Zhang, George KK Lau, Fu-Sheng Wang 
World J Gastroenterol 21(12):3554-3563. Published online Mar 28, 2015. doi: 10.3748/wjg.v21.i12.3554
Hepatectomy with primary closure of common bile duct for hepatolithiasis combined with choledocholithiasis 
Chang-Ku Jia, Jie Weng, You-Ke Chen, Qing-Zhuang Yang, Yu Fu, Qi-Fan Qin, Wei-Ming Yu 
World J Gastroenterol 21(12):3564-3570. Published online Mar 28, 2015. doi: 10.3748/wjg.v21.i12.3564
Retrospective Study
Thiopurine metabolites variations during co-treatment with aminosalicylates for inflammatory bowel disease: Effect of N-acetyl transferase polymorphisms 
Gabriele Stocco, Eva Cuzzoni, Sara De Iudicibus, Diego Favretto, Noelia Malusà, Stefano Martelossi, Elena Pozzi, Paolo Lionetti, Alessandro Ventura, Giuliana Decorti 
World J Gastroenterol 21(12):3571-3578. Published online Mar 28, 2015. doi: 10.3748/wjg.v21.i12.3571
Computed tomography-guided percutaneous core needle biopsy in pancreatic tumor diagnosis 
Chiang J Tyng, Maria Fernanda A Almeida, Paula NV Barbosa, Almir GV Bitencourt, José Augusto AG Berg, Macello S Maciel, Felipe JF Coimbra, Luiz Henrique O Schiavon, Maria Dirlei Begnami, Marcos D Guimarães, Charles E Zurstrassen, Rubens Chojniak 
World J Gastroenterol 21(12):3579-3586. Published online Mar 28, 2015. doi: 10.3748/wjg.v21.i12.3579
Appropriate empirical antibiotic use and 30-d mortality in cirrhotic patients with bacteremia 
Hyun Park, Ki Jun Jang, Won Jang, Sang Hoon Park, Ji Young Park, Tae Joo Jeon, Tae Hoon Oh, Won Chang Shin, Won-Choong Choi, Dong Hyun Sinn 
World J Gastroenterol 21(12):3587-3592. Published online Mar 28, 2015. doi: 10.3748/wjg.v21.i12.3587
Formalin irrigation for hemorrhagic chronic radiation proctitis 
Teng-Hui Ma, Zi-Xu Yuan, Qing-Hua Zhong, Huai-Ming Wang, Qi-Yuan Qin, Xiao-Xia Chen, Jian-Ping Wang, Lei Wang 
World J Gastroenterol 21(12):3593-3598. Published online Mar 28, 2015. doi: 10.3748/wjg.v21.i12.3593
Poor prognosis for hepatocellular carcinoma with transarterial chemoembolization pre-transplantation: Retrospective analysis 
Hai-Lin Li, Wen-Bin Ji, Rui Zhao, Wei-Dong Duan, Yong-Wei Chen, Xian-Qiang Wang, Qiang Yu, Ying Luo, Jia-Hong Dong 
World J Gastroenterol 21(12):3599-3606. Published online Mar 28, 2015. doi: 10.3748/wjg.v21.i12.3599
Endoscopic ultrasound-guided deep and large biopsy for diagnosis of gastric infiltrating tumors with negative malignant endoscopy biopsies 
Xin-Xin Zhou, Hang-Hai Pan, Ali Usman, Feng Ji, Xi Jin, Wei-Xiang Zhong, Hong-Tan Chen 
World J Gastroenterol 21(12):3607-3613. Published online Mar 28, 2015. doi: 10.3748/wjg.v21.i12.3607
Cholecystectomy does not significantly increase the risk of fatty liver disease 
Hong-Gang Wang, Li-Zhen Wang, Hang-Jiang Fu, Peng Shen, Xiao-Dan Huang, Fa-Ming Zhang, Rui Xie, Xiao-Zhong Yang, Guo-Zhong Ji 
World J Gastroenterol 21(12):3614-3618. Published online Mar 28, 2015. doi: 10.3748/wjg.v21.i12.3614
Clinical Trials Study
Scintigraphy in laryngopharyngeal and gastroesophageal reflux disease: A definitive diagnostic test? 
Gregory L Falk, John Beattie, Alvin Ing, SE Falk, Michael Magee, Leticia Burton, Hans Van der Wall 
World J Gastroenterol 21(12):3619-3627. Published online Mar 28, 2015. doi: 10.3748/wjg.v21.i12.3619
Observational Study
Prevalence and factors associated with irritable bowel syndrome among university students in Lebanon: Findings from a cross-sectional study 
Christy Costanian, Hala Tamim, Shafika Assaad 
World J Gastroenterol 21(12):3628-3635. Published online Mar 28, 2015. doi: 10.3748/wjg.v21.i12.3628
Prospective Study
Helicobacter pylori and serum kynurenine-tryptophan ratio in patients with colorectal cancer 
Ayse Basak Engin, Bensu Karahalil, Ali Esat Karakaya, Atilla Engin 
World J Gastroenterol 21(12):3636-3643. Published online Mar 28, 2015. doi: 10.3748/wjg.v21.i12.3636
Colorectal cancers in ulcerative colitis from a low-prevalence area for colon cancer 
Devendra Desai, Sudeep Shah, Abhijit Deshmukh, Philip Abraham, Anand Joshi, Tarun Gupta, Ramesh Deshpande, Varun Khandagale, Siji George 
World J Gastroenterol 21(12):3644-3649. Published online Mar 28, 2015. doi: 10.3748/wjg.v21.i12.3644
Differences in clinical features of Crohn's disease and intestinal tuberculosis 
Xin Huang, Wang-Di Liao, Chen Yu, Yi Tu, Xiao-Lin Pan, You-Xiang Chen, Nong-Hua Lv, Xuan Zhu 
World J Gastroenterol 21(12):3650-3656. Published online Mar 28, 2015. doi: 10.3748/wjg.v21.i12.3650
Early kidney injury during long-term adefovir dipivoxil therapy for chronic hepatitis B 
Hong-Yu Jia, Feng Ding, Jian-Yang Chen, Jiang-Shan Lian, Yi-Min Zhang, Lin-Yan Zeng, Dai-Rong Xiang, Liang Yu, Jian-Hua Hu, Guo-Dong Yu, Huan Cai, Ying-Feng Lu, Lin Zheng, Lan-Juan Li, Yi-Da Yang 
World J Gastroenterol 21(12):3657-3662. Published online Mar 28, 2015. doi: 10.3748/wjg.v21.i12.3657
Randomized Controlled Trial
Doctor communication quality and Friends' attitudes influence complementary medicine use in inflammatory bowel disease 
Réme Mountifield, Jane M Andrews, Antonina Mikocka-Walus, Peter Bampton 
World J Gastroenterol 21(12):3663-3670. Published online Mar 28, 2015. doi: 10.3748/wjg.v21.i12.3663
Comparison of the efficacy and safety of sedation between dexmedetomidine-remifentanil and propofol-remifentanil during endoscopic submucosal dissection 
Namo Kim, Young-Chul Yoo, Sang Kil Lee, Hyunzu Kim, Hyang Mi Ju, Kyeong Tae Min 
World J Gastroenterol 21(12):3671-3678. Published online Mar 28, 2015. doi: 10.3748/wjg.v21.i12.3671
Systematic Reviews
Cholecystectomy and the risk of alimentary tract cancers: A systematic review 
Maria Coats, Sami M Shimi 
World J Gastroenterol 21(12):3679-3693. Published online Mar 28, 2015. doi: 10.3748/wjg.v21.i12.3679
Meta-Analysis
Association between cadherin-17 expression and pathological characteristics of gastric cancer: A meta-analysis 
Zi-Wen Long, Meng-Long Zhou, Jing-Wei Fu, Xian-Qun Chu, Ya-Nong Wang 
World J Gastroenterol 21(12):3694-3705. Published online Mar 28, 2015. doi: 10.3748/wjg.v21.i12.3694
Prognostic value of c-Met in colorectal cancer: A meta-analysis 
Yan Liu, Xiao-Feng Yu, Jian Zou, Zi-Hua Luo 
World J Gastroenterol 21(12):3706-3710. Published online Mar 28, 2015. doi: 10.3748/wjg.v21.i12.3706
Association of cholesterol with risk of pancreatic cancer: A meta-analysis 
Jia Wang, Wei-Jing Wang, Long Zhai, Dong-Feng Zhang 
World J Gastroenterol 21(12):3711-3719. Published online Mar 28, 2015. doi: 10.3748/wjg.v21.i12.3711
Effects of neutrophil elastase inhibitor in patients undergoing esophagectomy: A systematic review and meta-analysis 
Zhi-Qiang Wang, Long-Qi Chen, Yong Yuan, Wen-Ping Wang, Zhong-Xi Niu, Yu-Shang Yang, Jie Cai 
World J Gastroenterol 21(12):3720-3730. Published online Mar 28, 2015. doi: 10.3748/wjg.v21.i12.3720
Case Report
Pyogenic liver abscess caused by Fusobacterium in a 21-year-old immunocompetent male 
Zohair Ahmed, Saurabh K Bansal, Sonu Dhillon 
World J Gastroenterol 21(12):3731-3735. Published online Mar 28, 2015. doi: 10.3748/wjg.v21.i12.3731
Complicated fecal microbiota transplantation in a tetraplegic patient with severe Clostridium difficile infection 
Thorsten Brechmann, Justyna Swol, Veronika Knop-Hammad, Jörg Willert, Mirko Aach, Oliver Cruciger, Wolff Schmiegel, Thomas A Schildhauer, Uwe Hamsen 
World J Gastroenterol 21(12):3736-3740. Published online Mar 28, 2015. doi: 10.3748/wjg.v21.i12.3736
Fulminant phlegmonitis of the esophagus, stomach, and duodenum due to Bacillus thuringiensis 
Hisatake Matsumoto, Hiroshi Ogura, Masafumi Seki, Mitsuo Ohnishi, Takeshi Shimazu 
World J Gastroenterol 21(12):3741-3745. Published online Mar 28, 2015. doi: 10.3748/wjg.v21.i12.3741
Cetuximab and panitumumab in a patient with colon cancer and concomitant chronic skin disease: A potential beneficial effect on psoriasis vulgaris 
Ken Okamoto, Hiromichi Maeda, Takeo Shiga, Mai Shiga, Ken Dabanaka, Kazuhiro Hanazaki, Michiya Kobayashi 
World J Gastroenterol 21(12):3746-3749. Published online Mar 28, 2015. doi: 10.3748/wjg.v21.i12.3746
Cytomegalovirus colitis followed by ischemic colitis in a non-immunocompromised adult: A case report 
Tsuyoshi Hasegawa, Kazuki Aomatsu, Masanori Nakamura, Naoki Aomatsu, Keiho Aomatsu 
World J Gastroenterol 21(12):3750-3754. Published online Mar 28, 2015. doi: 10.3748/wjg.v21.i12.3750
Liver transplantation for recurrent posthepatectomy malignant hepatic angiomyolipoma: A case report 
Wen-Tao Wang, Zi-Qiang Li, Gui-Hui Zhang, Yuan Guo, Mu-Jian Teng 
World J Gastroenterol 21(12):3755-3758. Published online Mar 28, 2015. doi: 10.3748/wjg.v21.i12.3755
Gastritis cystica profunda in a previously unoperated stomach: A case report 
Xiong-Fei Yu, Li-Wen Guo, Shi-Tu Chen, Li-Song Teng 
World J Gastroenterol 21(12):3759-3762. Published online Mar 28, 2015. doi: 10.3748/wjg.v21.i12.3759