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Welcome to the World Journal of Gastroenterology

The World Journal of Gastroenterology (WJG) is an academic journal that publishes review articles and articles describing original research (basic or clinical) in the fields of gastroenterology, hepatology, gastrointestinal surgery, and gastrointestinal endoscopy. With the aim of advancing knowledge in each of these fields, the WJG gives topical priority to related major diseases and their clinical management; frequently published disease topics are gastric cancer, colorectal cancer, hepatocellular carcinoma, pancreatic cancer, inflammatory bowel disease, irritable bowel syndrome, hepatitis C, hepatitis B, nonalcoholic fatty liver disease, and liver transplantation. All articles published in the WJG comply with the Code of Conduct of the Committee on Publication Ethics (COPE) and the requirements of Academic Rules and Norms. No restrictions are imposed on numbers of words, figures (color, B/W), tables or references for any articles published in the WJG, allowing authors to tell a whole story. The WJG readership audience is global, representing 221 countries and regions, with an average number of 55,000 visits to the online journal per day. 

We encourage gastroenterologists and hepatologists worldwide to submit manuscripts to the WJG describing their original basic or clinical research findings that are of high academic value and which report new diagnostic techniques or summarize their treatment experiences.

The usual times related to all publication processes of the WJG are as follows: (1) From manuscript receipt to peer-review: 2-4 weeks; (2) From initial manuscript acceptance, with revisions, to return of the revised manuscript from the authors: 4-5 weeks; (3) From return of the revised manuscript from the authors to final acceptance: 1-2 weeks; (4) From final acceptance to an article in press: 2 days; and (5) From article in press designation to formal release of the electronic version and all online documentation: 2-9 weeks. The WJG’s acceptance rate: 35%. Submit here >>

2016 Published Issues

Damian Garcia-Olmo, MD, PhD, Doctor, Professor, Surgeon; Yosef Nasseri, MD, Doctor; Stephen Strom, PhD, Professor; Andrzej Tarnawski, DSc, MD, PhD, Professor


Science Citation Index Expanded(Web of Science), Current Contents/Clinical Medicine, Journal Citation Reports, Index Medicus, MEDLINE, PubMed, and PubMed Central.

Journal Metrics

The 2015 edition of Journal Citation Reports® released by Thomson Reuters (ISI) cites the 2015 impact factor for WJG as 2.787 (5-year impact factor: 2.848), ranking WJG as 38 among 78 journals in gastroenterology and hepatology (quartile in category Q2). SJR (SCImago Journal Rank) (2015): 1.076; IPP (Impact per Publication) (2015): 2.850; and SNIP (Source Normalized Impact per Paper) (2015): 1.137.


1007-9327 (print) and 2219-2840 (online)

Percutaneous ablation of pancreatic cancer  
Mirko D’Onofrio, Valentina Ciaravino, Riccardo De Robertis, Emilio Barbi, Roberto Salvia, Roberto Girelli, Salvatore Paiella, Camilla Gasparini, Nicolò Cardobi, Claudio Bassi
World J Gastroenterol 22(44):9661-9673. Published online Nov 28, 2016. doi: 10.3748/wjg.v22.i44.9661
Fatty liver is associated with an increased risk of diabetes and cardiovascular disease - Evidence from three different disease models: NAFLD, HCV and HIV  
Amedeo Lonardo, Stefano Ballestri, Giovanni Guaraldi, Fabio Nascimbeni, Dante Romagnoli, Stefano Zona, Giovanni Targher
World J Gastroenterol 22(44):9674-9693. Published online Nov 28, 2016. doi: 10.3748/wjg.v22.i44.9674
Epidemiology of pancreatic cancer  
Milena Ilic, Irena Ilic
World J Gastroenterol 22(44):9694-9705. Published online Nov 28, 2016. doi: 10.3748/wjg.v22.i44.9694
Galectin-3 and IL-33/ST2 axis roles and interplay in diet-induced steatohepatitis  
Nada Pejnovic, Ilija Jeftic, Nemanja Jovicic, Nebojsa Arsenijevic, Miodrag L Lukic
World J Gastroenterol 22(44):9706-9717. Published online Nov 28, 2016. doi: 10.3748/wjg.v22.i44.9706
Gene polymorphisms of pathogenic Helicobacter pylori in patients with different types of gastrointestinal diseases  
Yu-Li Chen, Xiao-Qiang Mo, Gan-Rong Huang, Yan-Qiang Huang, Juan Xiao, Li-Juan Zhao, Hong-Yu Wei, Qian Liang
World J Gastroenterol 22(44):9718-9726. Published online Nov 28, 2016. doi: 10.3748/wjg.v22.i44.9718
Basic Study
Infliximab does not increase colonic cancer risk associated to murine chronic colitis  
Loris R Lopetuso, Valentina Petito, Tiziano Zinicola, Cristina Graziani, Viviana Gerardi, Vincenzo Arena, Maria Emiliana Caristo, Andrea Poscia, Giovanni Cammarota, Alfredo Papa, Valerio Cufino, Alessandro Sgambato, Antonio Gasbarrini, Franco Scaldaferri
World J Gastroenterol 22(44):9727-9733. Published online Nov 28, 2016. doi: 10.3748/wjg.v22.i44.9727
Ex vivo response to mucosal bacteria and muramyl dipeptide in inflammatory bowel disease  
Claudia Loganes, Erica Valencic, Alessia Pin, Elisa Marini, Stefano Martelossi, Samuele Naviglio, Luigina De Leo, Tarcisio Not, Lorenzo Monasta, Alberto Tommasini, Annalisa Marcuzzi
World J Gastroenterol 22(44):9734-9743. Published online Nov 28, 2016. doi: 10.3748/wjg.v22.i44.9734
Angiopoietin-2/angiopoietin-1 as non-invasive biomarker of cirrhosis in chronic hepatitis C  
Angel Hernández-Bartolomé, Rosario López-Rodríguez, María Jesús Borque, Leticia González-Moreno, Yolanda Real-Martínez, Luisa García-Buey, Ricardo Moreno-Otero, Paloma Sanz-Cameno
World J Gastroenterol 22(44):9744-9751. Published online Nov 28, 2016. doi: 10.3748/wjg.v22.i44.9744
Transient receptor potential vanilloid 1-immunoreactive signals in murine enteric glial cells  
Masahiro Yamamoto, Mitsue Nishiyama, Seiichi Iizuka, Shigeaki Suzuki, Norihiro Suzuki, Sadakazu Aiso, Jin Nakahara
World J Gastroenterol 22(44):9752-9764. Published online Nov 28, 2016. doi: 10.3748/wjg.v22.i44.9752
Anticancer effect of linalool via cancer-specific hydroxyl radical generation in human colon cancer  
Kenichi Iwasaki, Yun-Wen Zheng, Soichiro Murata, Hiromu Ito, Ken Nakayama, Tomohiro Kurokawa, Naoki Sano, Takeshi Nowatari, Myra O Villareal, Yumiko N Nagano, Hiroko Isoda, Hirofumi Matsui, Nobuhiro Ohkohchi
World J Gastroenterol 22(44):9765-9774. Published online Nov 28, 2016. doi: 10.3748/wjg.v22.i44.9765
Naringenin protects against isoniazid- and rifampicin-induced apoptosis in hepatic injury  
Chao Wang, Rui-Qin Fan, Yan-Xiang Zhang, Hao Nie, Kan Li
World J Gastroenterol 22(44):9775-9783. Published online Nov 28, 2016. doi: 10.3748/wjg.v22.i44.9775
Effects of ω-3 fatty acids on toll-like receptor 4 and nuclear factor-κB p56 in lungs of rats with severe acute pancreatitis  
Bin Wang, Xiao-Wei Wu, Mei-Xia Guo, Min-Li Li, Xiao-Bing Xu, Xin-Xin Jin, Xiao-Hua Zhang
World J Gastroenterol 22(44):9784-9793. Published online Nov 28, 2016. doi: 10.3748/wjg.v22.i44.9784
Retrospective Study
Association between Helicobacter pylori status and metachronous gastric cancer after endoscopic resection  
Sung Bum Kim, Si Hyung Lee, Seung Il Bae, Yo Han Jeong, Se Hoon Sohn, Kyeong Ok Kim, Byung Ik Jang, Tae Nyeun Kim
World J Gastroenterol 22(44):9794-9802. Published online Nov 28, 2016. doi: 10.3748/wjg.v22.i44.9794
Prognostic implications of FGFR1 and MYC status in esophageal squamous cell carcinoma  
Dohee Kwon, Ji Yun Yun, Bhumsuk Keam, Young Tae Kim, Yoon Kyung Jeon
World J Gastroenterol 22(44):9803-9812. Published online Nov 28, 2016. doi: 10.3748/wjg.v22.i44.9803
IFIT1 polymorphisms predict interferon-α treatment efficiency for hepatitis B virus infection  
Dong-Ying Xie, Shi-Ming Wang, Jing-Min Yang, Liang-Hui Wang, Hong-Yan Chen, Cong Huai, Jia Shang, Qing Mao, Chun-Liang Lei, Guang-Han Luo, Ji Qian, Da-Ru Lu
World J Gastroenterol 22(44):9813-9821. Published online Nov 28, 2016. doi: 10.3748/wjg.v22.i44.9813
Therapeutic efficacy and stent patency of transhepatic portal vein stenting after surgery  
Ung Bae Jeon, Chang Won Kim, Tae Un Kim, Ki Seok Choo, Joo Yeon Jang, Kyung Jin Nam, Chong Woo Chu, Je Ho Ryu
World J Gastroenterol 22(44):9822-9828. Published online Nov 28, 2016. doi: 10.3748/wjg.v22.i44.9822
Observational Study
Attempt to calculate the prevalence and features of chronic hepatitis C infection in Tuscany using administrative data  
Caterina Silvestri, Simone Bartolacci, Pasquale Pepe, Mirko Monnini, Fabio Voller, Francesco Cipriani, Cristina Stasi
World J Gastroenterol 22(44):9829-9835. Published online Nov 28, 2016. doi: 10.3748/wjg.v22.i44.9829
Clinical features of HBsAg seroclearance in hepatitis B virus carriers in South Korea: A retrospective longitudinal study  
Young Min Park, Seong Gyu Lee
World J Gastroenterol 22(44):9836-9843. Published online Nov 28, 2016. doi: 10.3748/wjg.v22.i44.9836
Disease-specific miR-34a as diagnostic marker of non-alcoholic steatohepatitis in a Chinese population  
Xiao-Lin Liu, Qin Pan, Rui-Nan Zhang, Feng Shen, Shi-Yan Yan, Chao Sun, Zheng-Jie Xu, Yuan-Wen Chen, Jian-Gao Fan
World J Gastroenterol 22(44):9844-9852. Published online Nov 28, 2016. doi: 10.3748/wjg.v22.i44.9844
Prospective Study
Hepatitis E virus: Western Cape, South Africa  
Richie G Madden, Sebastian Wallace, Mark Sonderup, Stephen Korsman, Tawanda Chivese, Bronwyn Gavine, Aniefiok Edem, Roxy Govender, Nathan English, Christy Kaiyamo, Odelia Lutchman, Annemiek A van der Eijk, Suzan D Pas, Glynn W Webb, Joanne Palmer, Elizabeth Goddard, Sean Wasserman, Harry R Dalton, C Wendy Spearman
World J Gastroenterol 22(44):9853-9859. Published online Nov 28, 2016. doi: 10.3748/wjg.v22.i44.9853
Case Report
Spontaneous rupture of hepatic metastasis from a thymoma: A case report  
Ho Jae Kim, Yong Eun Park, Min Seo Ki, Se Ju Lee, Seung Hun Beom, Dai Hoon Han, Young Nyun Park, Jun Yong Park
World J Gastroenterol 22(44):9860-9864. Published online Nov 28, 2016. doi: 10.3748/wjg.v22.i44.9860
Pediatric living donor liver transplantation for congenital hepatic fibrosis using a mother’s graft with von Meyenburg complex: A case report  
Naoya Yamada, Yukihiro Sanada, Takumi Katano, Masahisa Tashiro, Yuta Hirata, Noriki Okada, Yoshiyuki Ihara, Atsushi Miki, Hideki Sasanuma, Taizen Urahashi, Yasunaru Sakuma, Koichi Mizuta
World J Gastroenterol 22(44):9865-9870. Published online Nov 28, 2016. doi: 10.3748/wjg.v22.i44.9865