Baishideng Publishing Group

Arkoudis NA, Karachaliou A, Triantafyllou G, Papadopoulos A, Koutserimpas C, Velonakis G. Spinal cord ischemia: The “snake bite sign”. World J Radiol 2025; 17(7): 110385

"The process of manuscript prepataion was objective and helped me. The editorial team was in very operative contact with me. Sometimes ..." [Read more]

"The process of manuscript prepataion was objective and helped me. The editorial team was in very operative contact with me. Sometimes the help desk didn't reply and then I apllied directly to editorial team. I appreciated for the big patiency of editorial team. I have an ask and suggestion for the manuscript preparation - it will be useful for authors if the language editing will provide the editorial team for proper payment. Thank you. " [Collapse]

Hakobyan VM, Petrosyan AA, Yeghiazaryan HH, Aleksanyan AY, Safaryan HH, Shmavonyan HH, Papazyan KT, Ayvazyan KH, Davtyan LG, Khachatryan AA, Sargsyan GS, Stepanyan SA. Removal of the sac during surgery for the repair of “giant” paraesophageal hernias. World J Gastrointest Surg 2025; 17(7): 106365

"We are very satisfied with the editorial and peer review process of this journal. The online submission system was user-friendly and ..." [Read more]

"We are very satisfied with the editorial and peer review process of this journal. The online submission system was user-friendly and efficient. The peer review reports were professional, constructive, and provided valuable guidance that helped us improve the quality of our manuscript. The editorial team maintained excellent communication throughout the process, and the final production quality, including formatting of figures and tables, met high academic standards. We appreciate the rigorous academic norms and the timely publication. We look forward to future collaboration with the journal. " [Collapse]

Zhou Y, Xu BT, Zhou HY, Shang ZT. Long noncoding ribonucleic acid ENST00000517482 enhances mesenchymal stem cell therapy against acute lung injury. World J Stem Cells 2025; 17(7): 109064

"Overall, this peer review process is efficient and professional. The review didn't take an unreasonably long time, so it didn't hold ..." [Read more]

"Overall, this peer review process is efficient and professional. The review didn't take an unreasonably long time, so it didn't hold back the progress of my research. The anonymous review mechanism effectively avoids subjective interference and ensures a fair environment. The review reports are highly targeted. They carefully point out areas for improvement, from refining research methods to tightening up the logic of conclusions, clearly guiding me in polishing the manuscript. Whether it's recognizing the innovation of the research or rigorously examining data details, the reviews demonstrate fairness and objectivity, helping me significantly enhance the quality of my manuscript. I'm looking forward to future collaborations with the journal and hope such a high - quality review model will continue to support academic exchanges. " [Collapse]

Wang K, Lin W, Han JY, Chen JY, Liu RH, Yu Z, Jin JJ. Differentiation of patient-specific induced pluripotent stem cells derived from type 1 diabetes peripheral blood mononuclear cells into pancreatic β-like cells. World J Stem Cells 2025; 17(7): 104607

"The World journal of gastrointestinal oncology has an excellent review process, no other problem with responses, the editorial team ..." [Read more]

"The World journal of gastrointestinal oncology has an excellent review process, no other problem with responses, the editorial team is accessible, and helps the process to be fast. The World journal of gastrointestinal oncology has an excellent review process, no other problem with responses, the editorial team is accessible, and helps the process to be fast. " [Collapse]

Pires AC, Uson Junior PLS. Enhancing T-cell response with monoclonal antibodies and chemotherapy in advanced gastric cancer. World J Gastrointest Oncol 2025; 17(7): 104806

"This editorial was our effort to critically appraise a basic study published in the World J Gastroenterol and we are very happy with ..." [Read more]

"This editorial was our effort to critically appraise a basic study published in the World J Gastroenterol and we are very happy with the editing process, peer reviews and article publishing process. The Journal is in its progressive journey with a higher impact factor this year and one of the reason is the quality of papers published in the WJG and we wish a better future to the Journal. Professor Joseph M Pappachan MD. FRCP, Corresponding author. " [Collapse]

Fernandez CJ, Jena S, Lakshmi V, Pappachan JM. Duodenal mucosal ablation: An emerging therapeutic concept for metabolic dysfunction-associated fatty liver disease. World J Gastroenterol 2025; 31(28): 109468

"All authors sincerely appreciate the professional and efficient publication process with World Journal of Gastroenterology. The ..." [Read more]

"All authors sincerely appreciate the professional and efficient publication process with World Journal of Gastroenterology. The editorial team maintained timely communication, and the reviewers provided constructive and insightful suggestions that helped improve the quality of our manuscript. We are grateful for the journal’s support and look forward to future collaboration. " [Collapse]

Ma L, Zhang MH, Xu YF, Hao YX, Niu XX, Li Y, Xing HC. Fecal microbiota transplantation: A promising treatment strategy for chronic liver disease. World J Gastroenterol 2025; 31(28): 105089

"I am extremely satisfied with the entire publication process at World Journal of Gastroenterology ! From submission to final ..." [Read more]

"I am extremely satisfied with the entire publication process at World Journal of Gastroenterology ! From submission to final publication, the editorial team maintained efficient and professional communication throughout. The reviewers provided rigorous yet constructive feedback that significantly improved the quality of the manuscript. The online submission system was user-friendly, the publication timeline was remarkably fast, and the layout design is clear and visually appealing. Particularly commendable is the journal's open-access policy, which ensures wide dissemination of research findings. I sincerely appreciate the high-quality service WJG provides to authors and its outstanding platform for showcasing academic work in the field of gastroenterology. I look forward to future collaborations with this esteemed journal! " [Collapse]

Wu HY, Han L, Ran T, Sun Y, Zhang QX, Huang T, Zou GL, Zhang Y, Zhou YM, Lin GY, Chen SJ, Wang JL, Pan C, Lu F, Pu HF, Zhao XK. FBP1 as a key regulator of focal adhesion kinase-mediated hepatic stellate cell activation: Multi-omics and experimental validation. World J Gastroenterol 2025; 31(28): 107361

"We sincerely appreciate the support and guidance provided by the journal throughout the invitation and peer-review process. The entire ..." [Read more]

"We sincerely appreciate the support and guidance provided by the journal throughout the invitation and peer-review process. The entire experience was smooth, professional, and well-organized. As a small suggestion, we believe the overall publication workflow could benefit from a slightly faster transition between the peer review and final publication stages. " [Collapse]

Li YH, Yao YN, Zhou SA, Wang Y. Regulation and intervention of stem cell differentiation by long non-coding RNAs: Mechanisms and therapeutic potential. World J Stem Cells 2025; 17(7): 107688

"All authors would like to express their gratitude to the reviewers of this thesis for their professional review comments, the ..." [Read more]

"All authors would like to express their gratitude to the reviewers of this thesis for their professional review comments, the modifications suggested by the reviewers are very helpful in improving the quality of this thesis; and to the editorial board for their professional editorial comments, and for their hard work and selflessness. " [Collapse]

Kang LM, Zhao YH, Yu FK, Zhang FW, Kang X. Two-point lifting/retracting technology for transumbilical single-port laparoscopic cholecystectomy based on the anatomical features of Calot's triangle. World J Gastrointest Surg 2025; 17(7): 104261

"I would like to express my sincere gratitude to the editorial team and the reviewers for their constructive feedback, professionalism, ..." [Read more]

"I would like to express my sincere gratitude to the editorial team and the reviewers for their constructive feedback, professionalism, and kind support throughout the entire publication process. From the initial submission to the final decision, every step was handled with transparency and efficiency, which greatly contributed to a positive and reassuring experience as an author. The reviewers’ insightful comments not only helped improve the quality of the manuscript but also demonstrated a genuine engagement with the research topic. I am truly pleased to have had the opportunity to publish in this journal, and I appreciate the commitment to scientific rigor and author support that was evident at every stage " [Collapse]

Sengul Bag F, Bag OF. Molecular and therapeutic effects of mesenchymal stem cell-derived exosomes on autoimmune diseases. World J Stem Cells 2025; 17(7): 107202

"The editors are conscientious and responsible, making the entire submission experience extremely smooth. They handle manuscripts and ..." [Read more]

"The editors are conscientious and responsible, making the entire submission experience extremely smooth. They handle manuscripts and various requests with high efficiency. What is particularly worth mentioning is that the submission system integrated with artificial intelligence technology has brought a great deal of convenience, significantly reducing the operational difficulties in the submission process. " [Collapse]

Ma WG, Si YX, Zhang YL, Gao WF, Dong YG, Li YQ, Xu ZF, Xi Q, Li ZZ. Combining acupuncture and mesenchymal stem cell therapy offers promise as a treatment for inflammatory bowel disease. World J Stem Cells 2025; 17(7): 105371

"First, our study prompts us to rethink the current indications for treatment. The conventional 'watchful waiting' strategy carries ..." [Read more]

"First, our study prompts us to rethink the current indications for treatment. The conventional 'watchful waiting' strategy carries risk. Our data shows 63% of our patients sought treatment precisely because their tumors grew during this observation period, potentially missing the optimal window for intervention. We propose that dynamic tumor growth and patient anxiety should be considered key indications for intervention, and that MDT evaluation is essential for these personalized decisions. Next, our study answers a core question of safety. We all know the greatest risk of standalone MWA is severe hemolysis. Our data demonstrates that pre-treatment with TACE eliminated this key complication. The mechanism is clear: TACE devascularizes the tumor, overcoming the 'heat sink effect' and enabling a safer procedure. With this safety bottleneck solved, efficacy was also dramatically improved. I also want to address the evaluation criteria. The standard RECIST criteria look only at 'size.' However, after our therapy, the tumor becomes a non-viable 'scar,' so measuring only size underestimates the true effect. We believe that for this therapy, the mRECIST criteria, which assess tumor 'viability,' provide a much more accurate reflection of success. Finally, our success extends beyond the images; it translates into tangible clinical benefits. Pre-treatment, nearly a third of patients were symptomatic. Post-treatment, the symptom improvement rate was approximately 93%. We also addressed the psychological burden, with a majority of anxious patients showing improvement. This demonstrates our strategy doesn't just treat a lesion—it restores patient well-being." Our study has several limitations, primarily its retrospective, single-center design and limited sample size. In conclusion, combining TACE with MWA is a safer and more effective strategy than TACE alone for large hepatic hemangiomas. These results provide a strong rationale for prospective, multicenter trials to establish this combination as a new standard of care. " [Collapse]

Sun JP, Zhou K, Pan J, Yang N, Sun XN, Zhao HT, Yang XB. Efficacy and safety of transcatheter arterial chemoembolization combined with microwave ablation for hepatic hemangiomas (> 5 cm). World J Gastroenterol 2025; 31(28): 109078

"The experience of publishing a paper in World Journal of Clinical Cases was impressive. The entire process was efficient and ..." [Read more]

"The experience of publishing a paper in World Journal of Clinical Cases was impressive. The entire process was efficient and transparent, fully demonstrating the professionalism and author-friendliness of a reputable journal. The submission system had a clear interface and was easy to operate. The status of the manuscript was updated in real time, greatly enhancing communication efficiency. The processing speed of the editorial department was commendable, with a prompt initial review and clear feedback. The reviewers' comments were detailed and to the point, directly addressing key issues and providing significant support for improving the quality of the paper. During the revision process, the editorial team was patient and coordinated well, responding promptly and meticulously to any questions, ensuring the accuracy and completeness of the revised manuscript. The final online publication and typesetting process was smooth and standardized, fully respecting the integrity of the academic work. " [Collapse]

Cheng LL, Tang B, Liu H, Zhu F, Chen YF, Zhang W. Thoughts and challenges of giant retroperitoneal liposarcoma: A case report. World J Clin Cases 2025; 13(26): 108308

"We sincerely thank the editorial team and reviewers of the World Journal of Clinical Oncology for their valuable time, critical ..." [Read more]

"We sincerely thank the editorial team and reviewers of the World Journal of Clinical Oncology for their valuable time, critical feedback, and support throughout the review process of our manuscript (Manuscript No: 107007). We are pleased to see our review article published and believe it will contribute meaningfully to the current understanding and future directions in clinical oncology. We appreciate the opportunity to share our work with the global scientific community and look forward to continued collaboration with the journal in the future. " [Collapse]

Gharia J, Pimplaskar S, Prajapati A. Revolutionizing cancer care: Bioprinting prostate cancer stem cells for targeted treatments. World J Clin Oncol 2025; 16(7): 107007

"We sincerely thank the editorial team and reviewers of the World Journal of Clinical Oncology for their valuable time, critical ..." [Read more]

"We sincerely thank the editorial team and reviewers of the World Journal of Clinical Oncology for their valuable time, critical feedback, and support throughout the review process of our manuscript (Manuscript No: 107788). We are pleased to see our review article published and believe it will contribute meaningfully to the current understanding and future directions in clinical oncology. We appreciate the opportunity to share our work with the global scientific community and look forward to continued collaboration with the journal in the future. " [Collapse]

Rana TA, Prajapati A. Unleashing the potential of ferroptosis, autophagy, and mitochondrial dynamics as emerging modalities in cancer treatment. World J Clin Oncol 2025; 16(7): 107788

"This is my 16th publication and I have submitted close to 50 papers. The professional services and excellent SOPs never cease to amaze ..." [Read more]

"This is my 16th publication and I have submitted close to 50 papers. The professional services and excellent SOPs never cease to amaze me. I rate this group as one of the best across the globe. That's the reason that I prefer to submit my best papers in this group first. " [Collapse]

Garg P, Tulina I, Ren DL, Bhattacharya K, Yagnik VD, Mahak G. TONEFACT: Can even advanced hemorrhoids be treated without surgery? A paradigm shift in the management of hemorrhoids. World J Gastrointest Surg 2025; 17(7): 107099

"The publication process was highly professional, and I appreciated the clarity, responsiveness, and continuous support provided ..." [Read more]

"The publication process was highly professional, and I appreciated the clarity, responsiveness, and continuous support provided throughout all stages. The evaluation system is well-structured and transparent, reflecting the journal’s strong commitment to scientific quality, editorial excellence, and a positive author experience. I felt that my work was handled with great care and respect, and I am grateful for the collaborative atmosphere fostered by the editorial team " [Collapse]

Sawaied IO, Samson AO, Golan E. Perceived risk of gastric cancer associated with long-term use of proton pump inhibitors: Bridging the gap. World J Clin Oncol 2025; 16(7): 107091

"Thanks to the efforts of the editorial team, this article has finally been published. We would like to express our gratitude to the ..." [Read more]

"Thanks to the efforts of the editorial team, this article has finally been published. We would like to express our gratitude to the editors for their hard work and assistance, and to the reviewers for their valuable feedback, which has made the article even more perfect. I hope the article can bring useful information to readers and open up new scientific ideas. " [Collapse]

Lin J, Chen YY, Wang SJ, Zhang Y, Huang HS, Zhang XQ. Epigenetic clocks of female reproductive system aging: Current application and future prospects. World J Obstet Gynecol 2025; 14(2): 108149

"We sincerely appreciate the efficient and transparent editorial process provided by the Baishideng Publishing Group. The peer review ..." [Read more]

"We sincerely appreciate the efficient and transparent editorial process provided by the Baishideng Publishing Group. The peer review was constructive, timely, and significantly enhanced the quality of our manuscript on intestinal ultrasound in ulcerative colitis. We commend the editorial team for their professionalism and attention to detail throughout the publication workflow. " [Collapse]

Pal P, Mateen MA, Pooja K, Rajadurai N, Gupta R, Tandan M, Duvvuru NR. Role of intestinal ultrasound in ulcerative colitis: A systematic review. World J Meta-Anal 2024; 12(3): 97210

19126 items Read more >>

Article Quality Tracking-Peer-Review

"Fecal transplants have been reported to improve the intestinal flora and improve UC and Crohn’s disease. In recent years, it has been ..." [Read more]

"Fecal transplants have been reported to improve the intestinal flora and improve UC and Crohn’s disease. In recent years, it has been reported that improving the intestinal flora improves liver damage. This is very interesting data, and it is believed that improving the intestinal flora improves bile acids and liver function. Please explain the mechanism behind this." [Collapse]

Ma L, Zhang MH, Xu YF, Hao YX, Niu XX, Li Y, Xing HC. Fecal microbiota transplantation: A promising treatment strategy for chronic liver disease. World J Gastroenterol 2025; 31(28): 105089

"The article “Stem cell therapy for diabetes: Advances, prospects, and challenges” provides a concise and informative overview of ..." [Read more]

"The article “Stem cell therapy for diabetes: Advances, prospects, and challenges” provides a concise and informative overview of current developments in stem cell–based approaches to treating diabetes, with a particular focus on induced pluripotent stem cells (iPSCs), mesenchymal stem cells (MSCs), and pancreatic islet transplantation. Zuo et al. present the current state of research, acknowledging both the exciting advancements and the persistent challenges. However, in some cases, the discussion leans toward emphasizing successful studies and positive trial outcomes, occasionally lacking a rigorous critique of failures or contradictory findings in the field. Thus, many of the cited studies report favorable outcomes, with limited discussion of trials that yielded null results or failed to translate to clinical efficacy. Authors clearly explain the underlying biological mechanisms, such as β-cell differentiation and paracrine immunomodulation by MSCs. Noteworthy advances are documented, including CRISPR-mediated immune evasion strategies, the development of encapsulation technologies to protect transplanted cells from host immunity, and the application of bioprinting to improve islet viability and function. The authors effectively describe the transition from basic research to clinical application, citing the first-in-human trials and the survival of stem cell–derived islets for over one year in patients. These contributions add clarity and momentum to the translational landscape of regenerative diabetes therapies. Authors also acknowledges unresolved issues that remain major barriers to clinical translation. These include the risks of tumorigenicity associated with iPSCs, the low engraftment efficiency of transplanted cells, and ongoing challenges with host immune rejection. Furthermore, the absence of long-term safety and efficacy data from randomized controlled trials highlights the need for more rigorous evidence before widespread adoption. The authors propose future directions such as 3D bioprinting of organoids, AI-guided combination therapies, and further refinement of genome editing techniques to enhance safety and immune compatibility. In conclusion, this review offers a well-informed and timely synthesis of the rapidly evolving field of stem cell therapy for diabetes. It successfully highlights promising technologies and recent clinical breakthroughs while acknowledging the complexity of translating laboratory innovations into durable, safe, and accessible therapies. Future iterations of this work would benefit from deeper critical analysis of contradictory evidence, expanded discussion on regulatory and ethical frameworks, and integration of emerging clinical trial data. Such enhancements would further strengthen its contribution to the scientific community and aid in shaping the direction of next-stage research and therapeutic development." [Collapse]

Zuo DB, Wang CH, Sang M, Sun XD, Chen GP, Ji KK. Stem cell therapy for diabetes: Advances, prospects, and challenges. World J Diabetes 2025; 16(7): 107344

"There is an Ethical problems, because hepatic hemangioma is benign tumor and it does not require any treatment. Transcatheter arterial ..." [Read more]

"There is an Ethical problems, because hepatic hemangioma is benign tumor and it does not require any treatment. Transcatheter arterial chemoembolization (TACE) and microwave ablation (MWA) have an adverse events, and so authors should make clear the definition of hepatic hemangioma which needs treatment. Authors only described the prognosis after 12 months. Authors should report the longer prognosis. " [Collapse]

"Well written manuscript, providing a detailed overview of MPox in neonates, including clinical presentation and particularities in ..." [Read more]

"Well written manuscript, providing a detailed overview of MPox in neonates, including clinical presentation and particularities in this age group, diagnosis, treatment options and therapeutic considerations, public health challenges and future implications. Specific mention of differential diagnostic consideration is also appreciated. Reference list is relevant and complete and the quality of language is good. Although I understand that MPox is rare in children, I'd suggest if possible to add some statements on the current epidemiology of MPox in this age group, or if it is only limited to case reports. " [Collapse]

Ikram E, Shaukat A, Qureshi MS, Saifullah M, Aslam MA, Mehdi AM. Monkeypox in neonates: A narrative review on clinical presentations, vertical transmission, and treatment challenges. World J Clin Infect Dis 2025; 14(1): 109806

"Vonoprazan (VPZ) is a new potassium antagonist that inhibits gastric acid secretion by blocking the binding of H+/K+-ATPase to K+ ..." [Read more]

"Vonoprazan (VPZ) is a new potassium antagonist that inhibits gastric acid secretion by blocking the binding of H+/K+-ATPase to K+ and preventing the entry of H+ into the gastric lumen. Existing studies demonstrate that VPZ-based treatment regimens, including triple therapy regimens with VPZ, amoxicillin, and clarithromycin, are both safe and effective in eradicating H. pylori. The multicenter randomized controlled trial discussed here was the first to compare triple therapy based on VPZ (VPZ/amoxicillin/clarithromycin) with the 14-day quadruple regimen based on bismuth in China. The results showed that triple therapy with VPZ achieved higher eradication rates compared to the quadruple regimen and with similar rates of side effects, making triple therapy with VPZ an important alternative (without bismuth) for eradicating H. pylori. Interestingly, no significant differences in eradication rates were observed between the 10- and 14-day treatments. However, to optimize results and reduce the incidence of antibiotic resistance, it is necessary to conduct extensive, multicenter studies in various countries worldwide." [Collapse]

Han RS, Hao JW, Wang T, Xin Z, Fan GX, Wang GD, Liu MM, Liu CX, Yang QZ, Yang ZW, Lv XY, Zhang C, Bian G, Meng J, Cui ZQ, Yun XJ, Cao JH, Li SH, Fan JF, Ma HG, Gao FY, Mao T, Tian ZB, Song XH, Yu YN. Efficacy and safety of triple therapy with vonoprazan for Helicobacter pylori eradication: A multicenter, prospective, randomized controlled trial. World J Gastroenterol 2025; 31(28): 109001

"The minireview "Key players in the breast cancer microenvironment: From fibroblasts to immune cells" by Sacide et al summarizes the ..." [Read more]

"The minireview "Key players in the breast cancer microenvironment: From fibroblasts to immune cells" by Sacide et al summarizes the role of tumor microenvironment in the immune invasion, therapy resistance and metastasis process in Breast cancer. This understanding will definitely help us to explore the breast cancer progression with new therapeutic approach. The minireview is well written and beautifully presented. The language and grammar is appropriate. The referencing is good. However, a description on role of tumor microenvironment on angiogenesis and angiogenic signaling could have been discussed. Overall The review is good and useful for the scientific community." [Collapse]

Çakal S, Er Urgancı B, Şimşek S. Key players in the breast cancer microenvironment: From fibroblasts to immune cells. World J Clin Oncol 2025; 16(7): 107339

"This study concerns a consensus reached by a group of experts from the Middle East, who, with the assistance of an internationally ..." [Read more]

"This study concerns a consensus reached by a group of experts from the Middle East, who, with the assistance of an internationally recognized German expert, formulated comprehensive guidelines on the treatment of Helicobacter pylori infection in the Middle East. It is well known that the prevalence of Helicobacter pylori infection in these countries is quite high in both adults and children. The development of antibiotic resistance in these countries is another obstacle to the effectiveness of treatment. In this sense, the formulation of these guidelines for treating Helicobacter pylori infection is useful and of practical importance, particularly about the risk of developing gastric cancer. Such activities should also be carried out in other parts of the world (e.g., Africa, Asia)." [Collapse]

Sharara AI, Alsohaibani FI, Alsaegh A, Al Ejji K, Al Awadhi S, Malfertheiner P, Karam SA, Al-Taweel T. First regional consensus on the management of Helicobacter pylori infection in the Middle East. World J Gastroenterol 2025; 31(27): 107138

"This is very interesting paper about heart failure after TIPS.Heart failure can be a complication after a transjugular intrahepatic ..." [Read more]

"This is very interesting paper about heart failure after TIPS.Heart failure can be a complication after a transjugular intrahepatic portosystemic shunt (TIPS) procedure, particularly in patients with pre-existing heart conditions or those with cirrhotic cardiomyopathy. While post-TIPS heart failure is relatively uncommon, it is crucial to understand the factors that can contribute to its development and to monitor patients closely for signs and symptoms. The author's fig4 EKG, BNP, and echocardiographic evaluations are simple and easy to understand." [Collapse]

Tomassoni DR, Schildkraut T, Ramachandran V, Cooke JC, Sawhney R. Cardiovascular risk assessment and predictors of cardiac decompensation after transjugular intrahepatic portosystemic shunt in patients with cirrhosis. World J Gastroenterol 2025; 31(27): 107740

"Kwon et al. reported that deep learning-based localization and lesion detection in capsule endoscopy for patients with suspected ..." [Read more]

"Kwon et al. reported that deep learning-based localization and lesion detection in capsule endoscopy for patients with suspected small-bowel bleeding. It maybe true the AI-based localization and lesion detection is very useful for the discovery of small-bowel bleeding in patients. If possible, authors should distribute these application for everyone examine their figures. If so, everyone could recognize the results of authors." [Collapse]

Kwon YS, Park TY, Kim SE, Park Y, Lee JG, Lee SP, Kim KO, Jang HJ, Yang YJ, Cho BJ. Deep learning-based localization and lesion detection in capsule endoscopy for patients with suspected small-bowel bleeding. World J Gastroenterol 2025; 31(27): 106819

"Excellently presented study. All points are very well taken. The article provides a comprehensive perspective on all contemporary ..." [Read more]

"Excellently presented study. All points are very well taken. The article provides a comprehensive perspective on all contemporary aspects of variceal hemorrhage management. The article is written so that it is recommended for gastroenterologists, general surgeons, hospitalists, and emergency medicine physicians. The Authors' effort constitutes a major contribution towards updating the current knowledge and understanding of the problem, and provides a foundation for database perfection. " [Collapse]

Kogilathota Jagirdhar GS, Okafor CC, Hussain M, Elmati PR, Ghumman A, Shah M, Surani S. Decline of the Sengstaken-Blakemore tube: A review of shifting practices in gastrointestinal hemorrhage management. World J Crit Care Med 2025; 14(3): 101856

"Only three articles examined are very few, the search should be expanded. also missing the PROSPERO membership number and the PRISMA ..." [Read more]

"Only three articles examined are very few, the search should be expanded. also missing the PROSPERO membership number and the PRISMA check-list. More detailed information on research should be provided to make it more rigorous. It would also be useful to specify the limitations of the study and what can be done in future studies to improve these limits Finally , a English editing is needed." [Collapse]

Yousif Mohamed AM, Salih M, Mohamed M, Abbas AE, Elsiddig M, Osama Omar M, Abdelsalam M, Elhag B, Mohamed N, Eisa Ahmed SH, Ahmed S, Mohamed D, Omar D. Comparative efficacy of cementless bipolar hemiarthroplasty and proximal femoral nail anti-rotation in unstable intertrochanteric fractures: A meta-analysis. World J Orthop 2025; 16(7): 107950

"Survival rates following radical surgery for gastric neuroendocrine neoplasms (g-NENs) are low, with high recurrence rates. Liu, et ..." [Read more]

"Survival rates following radical surgery for gastric neuroendocrine neoplasms (g-NENs) are low, with high recurrence rates. Liu, et al’s study addressed a critical issue in determining the postoperative prognosis of gastric neuroendocrine tumors by identifying the significance of lymph node ratio. Moreover, the random survival forest model, a machine-learning approach, surpasses traditional Cox proportional hazards models by enhancing predictive accuracy, clinical utility, and overall performance. This model’s ability to stratify patient risks and personalize survival predictions can aid in formulating targeted postoperative strategies, thus realizing an important aspect of personalized “precision medicine”. This paper is indicative for journal readers in this field." [Collapse]

Wang HN, An JH, Zong L. Estimating prognosis of gastric neuroendocrine neoplasms using machine learning: A step towards precision medicine. World J Gastrointest Oncol 2024; 16(12): 4548-4552

"Hepatocellular carcinoma (HCC) is one of the leading causes of cancer-related deaths due to late diagnosis and high recurrence rates. ..." [Read more]

"Hepatocellular carcinoma (HCC) is one of the leading causes of cancer-related deaths due to late diagnosis and high recurrence rates. Key biomarkers such as enhancer of zeste homolog 2 and fatty acid binding protein 5, along with other genetic biomarkers provide insights into HCC progression and potential therapeutic targets. This paper is indicative for journal readers in this field. " [Collapse]

Shodry S, Hasan YTN, Ahdi IR, Ulhaq ZS. Gene targets with therapeutic potential in hepatocellular carcinoma. World J Gastrointest Oncol 2024; 16(12): 4543-4547

"In this Editorial we comment on the interesting article by Liu, et al. The controlling nutritional status (CONUT) score was ..." [Read more]

"In this Editorial we comment on the interesting article by Liu, et al. The controlling nutritional status (CONUT) score was significantly associated with the prognosis of colorectal cancer patients, as supported by a large body of literature. Compared with other nutritional scores, the CONUT score might be introduced in clinical practice as an optimal prognostic nutritional index to predict patient outcome." [Collapse]

Berardi R, Chiariotti R, Mentrasti G. Is nutritional status a new indicator to use in clinical practice for colorectal cancer patients? World J Gastrointest Oncol 2024; 16(12): 4537-4542

"In this Editorial, they highlighted potential pitfalls in the current classification of mixed neuroendocrine non-neuroendocrine ..." [Read more]

"In this Editorial, they highlighted potential pitfalls in the current classification of mixed neuroendocrine non-neuroendocrine neoplasms and commented on challenges in the management of this heterogeneous group of malignancies in light of the paucity of evidence in the field. Improved biological and clinical knowledge were needed to generate robust classification schemes that will in turn provide clarity on the epidemiology of the disease, prognosis of affected patients and guidance for treatment tailoring. This paper is indicative for journal readers in this field." [Collapse]

Cives M, Porta C, Palmirotta R. Mixed neuroendocrine non-neuroendocrine tumors: The quest for evidence. World J Gastrointest Oncol 2024; 16(12): 4532-4536

"Gastric cancer remains a formidable global health concern with significant morbidity and mortality rates, despite the fact that ..." [Read more]

"Gastric cancer remains a formidable global health concern with significant morbidity and mortality rates, despite the fact that numerous advances have been made to improve conventional therapies. This Editorial article integrated network pharmacology insights with rigorous experimental validation to highlight the potential of Xiaojianzhong decoction as a multifaceted therapeutic approach for gastric cancer. This paper is indicative for journal readers in this field." [Collapse]

Cheng CH, Hao WR, Cheng TH. Exploring Xiaojianzhong decoction's potential in gastric cancer treatment: Integrative insights and experimental validation. World J Gastrointest Oncol 2024; 16(12): 4553-4558

"Mixed neuroendocrine non-neuroendocrine neoplasms constitute rare tumors that are located mainly in the gastrointestinal tract and ..." [Read more]

"Mixed neuroendocrine non-neuroendocrine neoplasms constitute rare tumors that are located mainly in the gastrointestinal tract and have high degrees of malignancy, and the frequency of these tumors has been increasing. The rare but steadily increasing number of gastrointestinal mixed neuroendocrine non-neuroendocrine neoplasms and pure neuroendocrine carcinomas require more radical treatment than slow-growing neuroendocrine neoplasms do and they are related to poor prognosis. They constitute a complicated diagnostic and therapeutic challenge. The current management strategy begins with surgery and is followed by chemotherapy. New chemotherapeutics and novel biological agents for targeted therapy, along with immunotherapy broaden the range of therapeutic options, providing promising outcomes. Effective management should be individualized and multidisciplinary. This paper is indicative for journal readers in this field." [Collapse]

Pavlidis ET, Galanis IN, Pavlidis TE. Critical considerations for the management of gastrointestinal mixed neuroendocrine non-neuroendocrine neoplasms and pure neuroendocrine carcinomas. World J Gastrointest Oncol 2024; 16(12): 4559-4564

"Within the intricate milieu of colorectal cancer (CRC) tissues, cancer-associated fibroblasts (CAFs) act as pivotal orchestrators, ..." [Read more]

"Within the intricate milieu of colorectal cancer (CRC) tissues, cancer-associated fibroblasts (CAFs) act as pivotal orchestrators, wielding considerable influence over tumor progression. Their review endeavored to dissect the multifaceted functions of CAFs within the realm of CRC, thereby highlighting their indispensability in fostering CRC malignant microenvironment and indicating the development of CAFs-targeted therapeutic interventions. Through a comprehensive synthesis of current knowledge, their review delineated insights into CAFs-mediated modulation of cancer cell proliferation, invasiveness, immune evasion, and neovascularization, elucidating the intricate web of interactions that sustain the pro-tumor metabolism and secretion of multiple factors. Additionally, recognizing the high level of heterogeneity within CAFs is crucial, as they encompass a range of subtypes, including myofibroblastic CAFs, inflammatory CAFs, antigen-presenting CAFs, and vessel-associated CAFs. Innovatively, the symbiotic relationship between CAFs and the intestinal microbiota is explored, shedding light on a novel dimension of CRC pathogenesis. Despite remarkable progress, the orchestrated dynamic functions of CAFs remain incompletely deciphered, underscoring the need for continued research endeavors for therapeutic advancements in CRC management. This review article is well written, and is informative for journal readers in this field." [Collapse]

Cui JY, Ma J, Gao XX, Sheng ZM, Pan ZX, Shi LH, Zhang BG. Unraveling the role of cancer-associated fibroblasts in colorectal cancer. World J Gastrointest Oncol 2024; 16(12): 4565-4578

"In their report, they assessed the prognostic value of gamma-glutamyl transpeptidase to platelet ratio (GPR) in early hepatitis B ..." [Read more]

"In their report, they assessed the prognostic value of gamma-glutamyl transpeptidase to platelet ratio (GPR) in early hepatitis B virus (HBV)-related hepatocellular carcinoma (HCC) patients. They evaluated the clinical utility of preoperative GPR in predicting outcomes for solitary HBV-related HCC patients using propensity score matching, restricted cubic spline, survival analyses and stratified analyses. Preoperative GPR levels facilitated recurrence monitoring and inform treatment strategies, potentially enhancing the quality of life for HCC patients. Although case report accompanied with some limitations for any conclusions, their report is interesting for journal readers in this field." [Collapse]

Yang CK, Wei ZL, Shen XQ, Jia YX, Wu QY, Wei YG, Su H, Qin W, Liao XW, Zhu GZ, Peng T. Prognostic utility of gamma-glutamyl transpeptidase to platelet ratio in patients with solitary hepatitis B virus-related hepatocellular carcinoma after hepatectomy. World J Gastrointest Oncol 2024; 16(12): 4579-4596

"Their developed and validated a promising machine learning architecture for predicting the 3-category survival times (cutoff values ..." [Read more]

"Their developed and validated a promising machine learning architecture for predicting the 3-category survival times (cutoff values of 3 years and 5 years) for four survival times (overall, disease-free, recurrence-free, and distant metastasis-free survival) and screened corresponding important variables. Fivefold cross validation and bootstrap validation were conducted. The models were evaluated with the area under the curve (AUC); moreover, the effectiveness of our variable screening methods was evaluated by comparing the models’ pre- and post-screening AUCs. SHapley Additive exPlanations were used to explain the decision-making process. Nomograms were drawn for various applications. Although their study design accompanied with some limitations for any conclusions, their results were informative for journal readers in this field." [Collapse]

Ji XL, Xu S, Li XY, Xu JH, Han RS, Guo YJ, Duan LP, Tian ZB. Prognostic prediction models for postoperative patients with stage I to III colorectal cancer based on machine learning. World J Gastrointest Oncol 2024; 16(12): 4597-4613

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Peer-Reviewers and Manuscript Statistics

Editorial board members: 2265

Peer-reviewers: 32522

Manuscripts received today: 9

Manuscript reviews today: 30

Unhandled manuscripts today: 128

Active peer-reviewers today: 1123

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