Comparison of the efficacy and safety of sedation between dexmedetomidine-remifentanil and propofol-remifentanil during endoscopic submucosal dissection
Namo Kim, Young-Chul Yoo, Hyunzu Kim, Hyang Mi Ju, Kyeong Tae Min, Department of Anesthesiology and Pain Medicine, Severance Hospital, Yonsei University College of Medicine, Seoul 120-752, South Korea
Sang Kil Lee, Department of Internal Medicine, Yonsei University College of Medicine, Seoul 120-752, South Korea
Hyunzu Kim, Department of Anesthesiology and Pain Medicine, Kangdong Sacred Heart Hospital, Hallym University College of Medicine, Seoul 134-701, South Korea
Author contributions: Kim N and Yoo YC contributed to conception and design, acquisition of data, or analysis and interpretation of data; Lee SK interpretation of data, revising the draft critically for important intellectual content; Kim H and Ju HM acquisition of data and analysis and interpretation of data; and Min KT substantial contributions to conception and design, acquisition of data, or analysis and interpretation of data, and final approval of the version to be published.
Ethics approval: The study was reviewed and approved by the Institutional Review Board of Severance Hospital, Yonsei University Health System No. 4-2012-0621.
Clinical trial registration: This study is registered at http://ClinicalTrials.gov. The registration identification number is No. NCT01920113.
Informed consent: All study participants, or their legal guardian, provided informed written consent prior to study enrollment.
Conflict-of-interest: The authors have no conflict-of-interest.
Data sharing: No additional data are available.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Kyeong Tae Min, MD, PhD, Department of Anesthesiology and Pain Medicine, Severance Hospital, Yonsei University College of Medicine, 50 Yonsei-ro, Seodaemun-gu, Seoul 120-752, South Korea. firstname.lastname@example.org
Telephone: +82-2-22274161 Fax: +82-2-22277897
Received: September 12, 2014
Peer-review started: September 14, 2014
First decision: October 14, 2014
Revised: November 17, 2014
Accepted: January 8, 2015
Article in press: January 8, 2015
Published online: March 28, 2015