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©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Mar 28, 2015; 21(12): 3593-3598
Published online Mar 28, 2015. doi: 10.3748/wjg.v21.i12.3593
Published online Mar 28, 2015. doi: 10.3748/wjg.v21.i12.3593
Formalin irrigation for hemorrhagic chronic radiation proctitis
Teng-Hui Ma, Zi-Xu Yuan, Qing-Hua Zhong, Huai-Ming Wang, Qi-Yuan Qin, Xiao-Xia Chen, Jian-Ping Wang, Lei Wang, Department of Colorectal Surgery, The Sixth Affiliated Hospital of Sun Yat-Sen University, Guangzhou 510655, Guangdong Province, China
Author contributions: Ma TH and Yuan ZX contributed equally to the work; Wang L and Wang JP conceived the study; Ma TH, Yuan ZX, Zhong QH and Wang HM designed and performed the work; Ma TH, Yuan ZX, Qin QY and Chen XX performed acquisition, analysis and interpretation of data; Ma TH and Yuan ZX drafted the manuscript; Wang L and Wang JP revised the manuscript; all authors approved the final version to be published.
Supported by National Natural Science Foundation of China, No. 81372566; and Chinese Ministry of Education’s “Doctor Station” Foundation, No. 20120171110096.
Ethics approval: The study was approved by the Ethical Committee of the Sixth Affiliated Hospital of Sun Yat-Sen University and met the guidelines of the local responsible governmental agency.
Informed consent: Informed consent was waived due to the retrospective nature of the study.
Conflict-of-interest: The authors have no conflicts of interests related to the publication of this study.
Data sharing: No additional data are available.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Lei Wang, MD, PhD, Department of Colorectal Surgery, The Sixth Affiliated Hospital of Sun Yat-Sen University, 26 Yuancunerheng Road, Guangzhou 510655, Guangdong Province, China. wangl9@mail.sysu.edu.cn
Telephone: +86-20-38767131 Fax: +86-20-38254221
Received: August 29, 2014
Peer-review started: September 1, 2014
First decision: September 15, 2014
Revised: October 19, 2014
Accepted: January 8, 2015
Article in press: January 8, 2015
Published online: March 28, 2015
Peer-review started: September 1, 2014
First decision: September 15, 2014
Revised: October 19, 2014
Accepted: January 8, 2015
Article in press: January 8, 2015
Published online: March 28, 2015
Core Tip
Core tip: The study describes a modified topical formalin irrigation procedure that was well tolerated with long-term effectiveness for refractory hemorrhagic chronic radiation proctitis. The method focused on improving safety and reducing complications. The advantages of the procedure were as follows: protection of internal sphincter (spinal epidural anesthesia and the clasp-knife position provide full anal dilatation instead of dilatation by an anal retractor); protection of proximal normal colonic mucosa (Foley catheter inserted into the proximal sigmoid cavity to prevent damage from formalin backflow); targeting of the lesion area; and well-controlled volume and irrigation time.