Published online Mar 28, 2015. doi: 10.3748/wjg.v21.i12.3759
Peer-review started: August 3, 2014
First decision: August 27, 2014
Revised: September 11, 2014
Accepted: November 18, 2014
Article in press: November 19, 2014
Published online: March 28, 2015
Gastritis cystica profunda is a relatively rare disease, usually observed at anastomotic sites in stomachs of patients that have undergone gastric procedures. We present the rare case of an elevated lesion in the anterior wall of the gastric antrum of a 43-year-old Chinese woman who had never undergone gastric surgery and had no gastrointestinal tract symptoms. Although the physical examination and laboratory data showed no abnormalities, endoscopic ultrasonography revealed an anechoic cystic structure. Abdominal computed tomography and magnetic resonance imaging showed the gastric wall of the greater curvature of the antrum was markedly and irregularly thickened, and mild to moderate enhancement was observed around the lesion with no enhancement in the central portion, suggestive of a gastrointestinal stromal tumor. The patient underwent a distal gastric resection of the 2.5 cm × 1.5 cm lesion. A postoperative pathologic examination showed dilated cystic glands in the muscularis mucosa and submucosal layers and erosion of the mucosal surface of the tumor, confirming the diagnosis of gastritis cystica profunda without malignancy.
Core tip: Gastritis cystica profunda is a rare disease characterized by polypoid hyperplasia and cystic dilatation of the gastric glands extending into the submucosa of the stomach. It is typically only found in the stomach after gastric surgery, however, we encountered a rare case of gastritis cystica profunda in a 43-year-old Chinese woman who had never undergone gastric surgery. The elevated lesion in the anterior wall of the gastric antrum was discovered by endoscopic ultrasonography, and marked and irregular thickening of the gastric wall was observed with computed tomography and magnetic resonance imaging.