Retrospective Study
Copyright ©The Author(s) 2015.
World J Gastroenterol. Mar 28, 2015; 21(12): 3614-3618
Published online Mar 28, 2015. doi: 10.3748/wjg.v21.i12.3614
Table 1 Demographics and clinical characteristics of the subjects according to cholecystectomy
With cholecystectomy (n = 949)Without cholecystectomy (n = 31479)P value
Age (yr)63 (54-73)49 (36-59)< 0.001
Sex (male/female)447/50222016/9463< 0.001
BMI (kg/m2)24.26 (22.55-26.65)23.92 (21.71-26.09)< 0.001
SBP (mmHg)131 (121-141)125 (116-135)< 0.001
DBP (mmHg)80 (72-88)77 (69-86)< 0.001
FPG (mmol/L)5.41 (4.97-5.99)5.04 (4.68-5.47)< 0.001
TC (mmol/L)5.07 (4.43-5.74)4.93 (4.34-5.57)< 0.001
TG (mmol/L)1.28 (0.92-1.74)1.14 (0.82-1.67)< 0.001
HDL cholesterol (mmol/L)1.28 (1.10-1.51)1.28 (1.09-1.50)0.240
LDL cholesterol (mmol/L)2.88 (2.37-3.42)2.88 (2.39-3.40)0.987
ALT (U/L)19 (14-26)19 (14-27)0.132
AST (U/L)20 (17-24)20 (17-24)0.237
GGT (U/L)22 (16-33)22 (15-36)0.243
Albumin (g/L)47.7 (45.8-49.3)47.7 (45.6-49.6)0.835
SUA (mmol/L)327 (265-379)329 (275-386)0.070
FLD (yes/no)445/50412003/19476< 0.001
The data are expressed as the median (IQR) due to abnormal distribution. Mann-Whitney U and χ2 test were performed. BMI: Body mass index; SBP: Systolic blood pressure; DBP: Diastolic blood pressure; FPG: Fasting plasma glucose; TC: Total cholesterol; TG: Triglycerides; HDL: High-density lipoprotein; LDL: Low-density lipoprotein; ALT: Alanine aminotransferase; AST: Aspartate aminotransferase; GGT: Gamma-glutamyl transpeptidase; SUA: Serum uric acid; FLD: Fatty liver disease.
Table 2 Logistic regression analysis of odds ratios for fatty liver disease relative to cholecystectomy
Multivariate regression analysis
OR95%CIP value
Cholecystectomy (not adjusted)1.4331.259-1.631< 0.001
Cholecystectomy (adjusted1)1.0960.939-1.2790.245
1Data were adjusted for age, gender, BMI, SBP, DBP, FPG, TC, TG, HDL cholesterol, LDL cholesterol, ALT, AST, GGT, albumin, and SUA. BMI: Body mass index; SBP: Systolic blood pressure; DBP: Diastolic blood pressure; FPG: Fasting plasma glucose; TC: Total cholesterol; TG: Triglycerides; HDL: High-density lipoprotein; LDL: Low-density lipoprotein; ALT: Alanine aminotransferase; AST: Aspartate aminotransferase; GGT: Gamma-glutamyl transpeptidase; SUA: Serum uric acid.