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Open-Access Journal
Editorial
Update on the management of pancreatic cancer: Surgery is not enough 
Daniel Ansari, Adam Gustafsson, Roland Andersson 
World J Gastroenterol 21(11):3157-3165. Published online Mar 21, 2015. doi: 10.3748/wjg.v21.i11.3157
Contra-lateral liver lobe hypertrophy after unilobar Y90 radioembolization: An alternative to portal vein embolization? 
Jin-Yao Teo, Brian KP Goh 
World J Gastroenterol 21(11):3170-3173. Published online Mar 21, 2015. doi: 10.3748/wjg.v21.i11.3170
Review
Nuclear factor kappa B role in inflammation associated gastrointestinal malignancies 
Sahil Gambhir, Dinesh Vyas, Michael Hollis, Apporva Aekka, Arpita Vyas 
World J Gastroenterol 21(11):3174-3183. Published online Mar 21, 2015. doi: 10.3748/wjg.v21.i11.3174
Updates in vaccination: Recommendations for adult inflammatory bowel disease patients 
Khadija Chaudrey, Michelle Salvaggio, Aftab Ahmed, Sultan Mahmood, Tauseef Ali 
World J Gastroenterol 21(11):3184-3196. Published online Mar 21, 2015. doi: 10.3748/wjg.v21.i11.3184
Hyponatremia in cirrhosis: Pathophysiology and management 
Savio John, Paul J Thuluvath 
World J Gastroenterol 21(11):3197-3205. Published online Mar 21, 2015. doi: 10.3748/wjg.v21.i11.3197
Novel CD9-targeted therapies in gastric cancer 
Yoko Murayama, Kenji Oritani, Shusaku Tsutsui 
World J Gastroenterol 21(11):3206-3213. Published online Mar 21, 2015. doi: 10.3748/wjg.v21.i11.3206
Ghrelin-ghrelin O-acyltransferase system in the pathogenesis of nonalcoholic fatty liver disease 
Shao-Ren Zhang, Xiao-Ming Fan 
World J Gastroenterol 21(11):3214-3222. Published online Mar 21, 2015. doi: 10.3748/wjg.v21.i11.3214
Minireviews
Biomarkers in nonalcoholic fatty liver disease-the emperor has no clothes? 
Madhusudana Girija Sanal 
World J Gastroenterol 21(11):3223-3231. Published online Mar 21, 2015. doi: 10.3748/wjg.v21.i11.3223
Mitochondrial uncoupling protein 2 and pancreatic cancer: A new potential target therapy 
Massimo Donadelli, Ilaria Dando, Elisa Dalla Pozza, Marta Palmieri 
World J Gastroenterol 21(11):3232-3238. Published online Mar 21, 2015. doi: 10.3748/wjg.v21.i11.3232
Basic Study
Effects of urotensin-II on cytokines in early acute liver failure in mice 
Liang-Ming Liu, Liang Zhao, Dong-Yu Liang, Fang-Ping Yu, Chang-Gen Ye, Wen-Juan Tu, Tong Zhu 
World J Gastroenterol 21(11):3239-3244. Published online Mar 21, 2015. doi: 10.3748/wjg.v21.i11.3239
MicroRNA-1290 promotes esophageal squamous cell carcinoma cell proliferation and metastasis 
Ming Li, Xiao-Yan He, Zhi-Mei Zhang, Shuo Li, Li-Hua Ren, Ri-Sheng Cao, Ya-Dong Feng, Yin-Lin Ji, Ye Zhao, Rui-Hua Shi 
World J Gastroenterol 21(11):3245-3255. Published online Mar 21, 2015. doi: 10.3748/wjg.v21.i11.3245
High-mobility group box 1 expression and lymph node metastasis in intrahepatic cholangiocarcinoma 
Yun-Fei Xu, Fu-Jun Ge, Bo Han, Xiao-Qing Yang, Hong Su, An-Cheng Zhao, Ming-Hong Zhao, Yu-Bao Yang, Jie Yang 
World J Gastroenterol 21(11):3256-3265. Published online Mar 21, 2015. doi: 10.3748/wjg.v21.i11.3256
Case Control Study
Hepatitis E in hemodialysis and kidney transplant patients in south-east Italy 
Gaetano Scotto, Filippo Aucella, Giuseppe Grandaliano, Domenico Martinelli, Mario Querques, Antonio Gesuete, Barbara Infante, Paolo Delli Carri, Salvatore Massa, Giovanna Salatino, Fabio Bulla, Vincenzina Fazio 
World J Gastroenterol 21(11):3266-3273. Published online Mar 21, 2015. doi: 10.3748/wjg.v21.i11.3266
Retrospective Cohort Study
Ratio of metastatic lymph nodes is more important for rectal cancer patients treated with preoperative chemoradiotherapy 
In Ja Park, Chang Sik Yu, Seok-Byung Lim, Yong Sik Yoon, Chan Wook Kim, Tae Won Kim, Jong Hoon Kim, Jin Cheon Kim 
World J Gastroenterol 21(11):3274-3281. Published online Mar 21, 2015. doi: 10.3748/wjg.v21.i11.3274
Retrospective Study
Real-life outcome of anti-tumor necrosis factor α in the ambulatory treatment of ulcerative colitis 
Enayatullah Baki, Philipp Zwickel, Anna Zawierucha, Robert Ehehalt, Daniel Gotthardt, Wolfgang Stremmel, Annika Gauss 
World J Gastroenterol 21(11):3282-3290. Published online Mar 21, 2015. doi: 10.3748/wjg.v21.i11.3282
Hepcidin/ferroportin expression levels involve efficacy of pegylated-interferon plus ribavirin in hepatitis C virus-infected liver 
Motoyuki Kohjima, Tsuyoshi Yoshimoto, Munechika Enjoji, Nobuyoshi Fukushima, Kunitaka Fukuizumi, Tsukasa Nakamura, Miho Kurokawa, Nao Fujimori, Yusuke Sasaki, Yasushi Shimonaka, Yusuke Murata, Susumu Koyama, Ken Kawabe, Kazuhiro Haraguchi, Yorinobu Sumida, Naohiko Harada, Masaki Kato, Kazuhiro Kotoh, Makoto Nakamuta 
World J Gastroenterol 21(11):3291-3299. Published online Mar 21, 2015. doi: 10.3748/wjg.v21.i11.3291
Hepatectomy vs radiofrequency ablation for colorectal liver metastasis: A propensity score analysis 
Huisong Lee, Jin Seok Heo, Yong Beom Cho, Seong Hyeon Yun, Hee Cheol Kim, Woo Yong Lee, Seong Ho Choi, Dong Wook Choi 
World J Gastroenterol 21(11):3300-3307. Published online Mar 21, 2015. doi: 10.3748/wjg.v21.i11.3300
Significant risk and associated factors of active tuberculosis infection in Korean patients with inflammatory bowel disease using anti-TNF agents 
Eun Soo Kim, Geun Am Song, Kwang Bum Cho, Kyung Sik Park, Kyeong Ok Kim, Byung Ik Jang, Eun Young Kim, Seong Woo Jeon, Hyun Seok Lee, Chang Heon Yang, Yong Kook Lee, Dong Wook Lee, Sung Kook Kim, Tae Oh Kim, Jonghun Lee, Hyung Wook Kim, Sam Ryong Jee, Seun Ja Park, Hyun Jin Kim 
World J Gastroenterol 21(11):3308-3316. Published online Mar 21, 2015. doi: 10.3748/wjg.v21.i11.3308
High neutrophil-lymphocyte ratio indicates poor prognosis for acute-on-chronic liver failure after liver transplantation 
Bing-Yi Lin, Lin Zhou, Lei Geng, Zhi-Yun Zheng, Jun-Jun Jia, Jing Zhang, Jia Yao, Shu-Sen Zheng 
World J Gastroenterol 21(11):3317-3324. Published online Mar 21, 2015. doi: 10.3748/wjg.v21.i11.3317
Observational Study
Lack of correlation between Treg quantification assays in inflammatory bowel disease patients 
Gunnar Brandhorst, Darinka Todorova Petrova, Sebastian Weigand, Christoph Eberle, Nicolas von Ahsen, Jessica Schmitz, Frank Christian Schultze, Dirk Raddatz, Michael Karaus, Michael Oellerich, Philip D Walson 
World J Gastroenterol 21(11):3325-3329. Published online Mar 21, 2015. doi: 10.3748/wjg.v21.i11.3325
Recurrent anal fistulae: Limited surgery supported by stem cells 
Damian Garcia-Olmo, Hector Guadalajara, Ines Rubio-Perez, Maria Dolores Herreros, Paloma de-la-Quintana, Mariano Garcia-Arranz 
World J Gastroenterol 21(11):3330-3336. Published online Mar 21, 2015. doi: 10.3748/wjg.v21.i11.3330
Economic and medical benefits of ultrasound screenings for gallstone disease 
Hung-Ju Shen, Chung-Te Hsu, Tao-Hsin Tung 
World J Gastroenterol 21(11):3337-3343. Published online Mar 21, 2015. doi: 10.3748/wjg.v21.i11.3337
Weekly pattern of emergency room admissions for peptic ulcers: A population-based study 
Li-Ting Kao, Ming-Chieh Tsai, Herng-Ching Lin, Femi Pai, Cha-Ze Lee 
World J Gastroenterol 21(11):3344-3350. Published online Mar 21, 2015. doi: 10.3748/wjg.v21.i11.3344
Meta-Analysis
Diagnostic value of magnetic resonance cholangiopancreatography in choledocholithiasis 
Wen Chen, Jing-Jia Mo, Li Lin, Chao-Qun Li, Jian-Feng Zhang 
World J Gastroenterol 21(11):3351-3360. Published online Mar 21, 2015. doi: 10.3748/wjg.v21.i11.3351
Case Report
New therapeutic option for irritable bowel syndrome: Serum-derived bovine immunoglobulin 
Larry Good, Roxanne Rosario, Raymond Panas 
World J Gastroenterol 21(11):3361-3366. Published online Mar 21, 2015. doi: 10.3748/wjg.v21.i11.3361
Strongyloidiasis: A case with acute pancreatitis and a literature review 
Jasbir Makker, Bhavna Balar, Masooma Niazi, Myrta Daniel 
World J Gastroenterol 21(11):3367-3375. Published online Mar 21, 2015. doi: 10.3748/wjg.v21.i11.3367
Proposed case of mesalazine-induced cardiomyopathy in severe ulcerative colitis 
Kathryn Fleming, Andrew Ashcroft, Christopher Alexakis, Demitrios Tzias, Christopher Groves, Andrew Poullis 
World J Gastroenterol 21(11):3376-3379. Published online Mar 21, 2015. doi: 10.3748/wjg.v21.i11.3376
Colonic sarcoidosis: Unusual onset of a systemic disease 
Paola Erra, Sonia Crusco, Loredana Nugnes, Anna Maria Pollio, Gianni Di Pilla, Giuseppe Biondi, Giovanni Vigliardi 
World J Gastroenterol 21(11):3380-3387. Published online Mar 21, 2015. doi: 10.3748/wjg.v21.i11.3380
Giant gastrointestinal stromal tumour of rare sarcomatoid epithelioid subtype: Case study and literature review 
Gustaw Lech, Wojciech Korcz, Emilia Kowalczyk, Tomasz Guzel, Marcin Radoch, Ireneusz Wojciech Krasnodębski 
World J Gastroenterol 21(11):3388-3393. Published online Mar 21, 2015. doi: 10.3748/wjg.v21.i11.3388
Bronchial bleeding caused by recurrent pneumonia after radical esophagectomy for esophageal cancer 
Toshihiro Kitajima, Kota Momose, Seigi Lee, Shusuke Haruta, Masaki Ueno, Hisashi Shinohara, Sakashi Fujimori, Takeshi Fujii, Ryoji Takei, Tadasu Kohno, Harushi Udagawa 
World J Gastroenterol 21(11):3394-3401. Published online Mar 21, 2015. doi: 10.3748/wjg.v21.i11.3394
Endoscopic ultrasound-guided drainage of postoperative intra-abdominal abscesses 
Koichiro Mandai, Koji Uno, Kenjiro Yasuda 
World J Gastroenterol 21(11):3402-3408. Published online Mar 21, 2015. doi: 10.3748/wjg.v21.i11.3402
Pediatric gastric cancer presenting with massive ascites 
Chien-Heng Lin, Wei-Ching Lin, I-Hsiu Lai, Shu-Fen Wu, Kang-Hsi Wu, An-Chyi Chen 
World J Gastroenterol 21(11):3409-3413. Published online Mar 21, 2015. doi: 10.3748/wjg.v21.i11.3409
Hepatocellular carcinoma with concomitant hepatic angiomyolipoma and cavernous hemangioma in one patient 
Xiao-Wen Ge, Hai-Ying Zeng, Akesu Su-Jie, Min Du, Yuan Ji, Yun-Shan Tan, Ying-Yong Hou, Jian-Fang Xu 
World J Gastroenterol 21(11):3414-3419. Published online Mar 21, 2015. doi: 10.3748/wjg.v21.i11.3414
Partial splenectomy using a laparoscopic bipolar radiofrequency device: A case report 
Wei-Dong Wang, Jie Lin, Zhi-Qiang Wu, Qing-Bo Liu, Jing Ma, Xiao-Wu Chen 
World J Gastroenterol 21(11):3420-3424. Published online Mar 21, 2015. doi: 10.3748/wjg.v21.i11.3420
Congenital left intrahepatic bile duct draining into gastric wall mimicking biliary reflux gastritis 
Jian Guan, Ling Zhang, Jian-Ping Chu, Shao-Chun Lin, Zi-Ping Li 
World J Gastroenterol 21(11):3425-3428. Published online Mar 21, 2015. doi: 10.3748/wjg.v21.i11.3425
Rare case of Helicobacter pylori-positive multiorgan IgG4-related disease and gastric cancer 
Min Li, Qiang Zhou, Kun Yang, David R Brigstock, Lu Zhang, Ming Xiu, Li Sun, Run-Ping Gao 
World J Gastroenterol 21(11):3429-3434. Published online Mar 21, 2015. doi: 10.3748/wjg.v21.i11.3429
Gastrointestinal hemorrhage due to ileal metastasis from primary lung cancer 
Wei Liu, Wei Zhou, Wei-Lin Qi, Ya-Dan Ma, Yun-Yun Xu 
World J Gastroenterol 21(11):3435-3440. Published online Mar 21, 2015. doi: 10.3748/wjg.v21.i11.3435
Icotinib plus gemcitabine for metastatic pancreatic cancer: A case report 
Jing Zhao, Hong Shen, Han-Guang Hu, Jian-Jin Huang 
World J Gastroenterol 21(11):3441-3446. Published online Mar 21, 2015. doi: 10.3748/wjg.v21.i11.3441
Letters To The Editor
Cobalamin deficiency as an extra intestinal manifestation of Helicobacter pylori infection 
Emmanuel Andrès 
World J Gastroenterol 21(11):3447-3448. Published online Mar 21, 2015. doi: 10.3748/wjg.v21.i11.3447