Retrospective Study
Copyright ©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Mar 28, 2015; 21(12): 3579-3586
Published online Mar 28, 2015. doi: 10.3748/wjg.v21.i12.3579
Computed tomography-guided percutaneous core needle biopsy in pancreatic tumor diagnosis
Chiang J Tyng, Maria Fernanda A Almeida, Paula NV Barbosa, Almir GV Bitencourt, José Augusto AG Berg, Macello S Maciel, Felipe JF Coimbra, Luiz Henrique O Schiavon, Maria Dirlei Begnami, Marcos D Guimarães, Charles E Zurstrassen, Rubens Chojniak
Chiang J Tyng, Maria Fernanda A Almeida, Macello S Maciel, Luiz Henrique O Schiavon, Marcos D Guimarães, Charles E Zurstrassen, Rubens Chojniak, Paula N V Barbosa, Almir G V Bitencourt, José Augusto A G Berg, Department of Imaging, AC Camargo Cancer Center, São Paulo, SP 09015-010, Brazil
Felipe JF Coimbra, Maria Dirlei Begnami, Department of Abdominal Surgery, AC Camargo Cancer Center, São Paulo, SP 09015-010, Brazil
Author contributions: Tyng CJ, Barbosa PNV, Coimbra FJF and Chojniak R designed the research; Tyng CJ, Barbosa PNV, Almeida MFA, Bitencourt AGV, Schiavon LHO, Berg JAAG and Maciel MS performed the research; Almeida MFA, Bitencourt AGV, Berg JAAG, Maciel MS, Begnami MD, Guimarães MD and Zurstrassen CE analyzed the data; all authors wrote and revised the paper.
Ethics approval: The study was reviewed and approved by the Antonio Prudente Foundation and the AC Camargo Cancer Center Institutional Review Board.
Informed consent: All study participants, or their legal guardian, provided written informed consent prior to study enrollment.
Conflict-of-interest: The authors have no conflict of interest to declare.
Data sharing: No additional data are available.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See:
Correspondence to: Almir GV Bitencourt, MD, PhD, Department of Imaging, AC Camargo Cancer Center, R Prof Antonio Prudente 211, São Paulo, SP 09015-010, Brazil.
Telephone: +55-11-21895000-1050 Fax: +55-11-21895000-1050
Received: August 27, 2014
Peer-review started: August 28, 2014
First decision: September 27, 2014
Revised: December 23, 2014
Accepted: January 16, 2015
Article in press: January 16, 2015
Published online: March 28, 2015
Core Tip

Core tip: Histopathologic analysis is often necessary to confirm the diagnosis of pancreatic tumors and aid in treatment planning. Various techniques, such as imaging-guided percutaneous, endoscopic, and surgical biopsies, can be used to obtain material for the cytologic or histologic analysis. In the present study, computed tomography-guided percutaneous core needle biopsies of pancreatic lesions were associated with few complications and 98.1% diagnostic accuracy. The safety and high diagnostic success rate renders this method an excellent minimally invasive option for diagnostic confirmation of solid pancreatic lesions.