Systematic Reviews
Copyright ©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Mar 28, 2015; 21(12): 3679-3693
Published online Mar 28, 2015. doi: 10.3748/wjg.v21.i12.3679
Cholecystectomy and the risk of alimentary tract cancers: A systematic review
Maria Coats, Sami M Shimi
Maria Coats, Sami M Shimi, Department of Surgery, Ninewells Hospital and Medical School, University of Dundee, Dundee DD1 9SY, Scotland
Author contributions: Coats M and Shimi SM equally contributed to this paper.
Conflict-of-interest: The authors declare no conflict of interest.
Data sharing: No additional data are available.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See:
Correspondence to: Sami M Shimi, FRCS, Department of Surgery, Ninewells Hospital and Medical School, University of Dundee, Nethergate, Dundee DD1 9SY, Scotland.
Telephone: +44-1382-383550 Fax: +44-1382-383615
Received: September 30, 2014
Peer-review started: September 30, 2014
First decision: November 14, 2014
Revised: December 5, 2014
Accepted: January 30, 2015
Article in press: January 30, 2015
Published online: March 28, 2015
Core Tip

Core tip: This systematic review explores the association between cholecystectomy and individual gastro-intestinal tract cancers and proposed mechanisms of carcinogenesis. The review finds no clear association between cholecystectomy and cancers of the gastro-intestinal tract.