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Open-Access Journal
Editorial
Field cancerisation in colorectal cancer: A new frontier or pastures past? 
Abhilasha Patel, Gyanendra Tripathi, Kishore Gopalakrishnan, Nigel Williams, Ramesh P Arasaradnam 
World J Gastroenterol 21(13):3763-3772. Published online Apr 7, 2015. doi: 10.3748/wjg.v21.i13.3763
Helicobacter pylori eradication in gastric diffuse large B cell lymphoma 
Semra Paydas 
World J Gastroenterol 21(13):3773-3776. Published online Apr 7, 2015. doi: 10.3748/wjg.v21.i13.3773
Current pharmacological therapies for nonalcoholic fatty liver disease/nonalcoholic steatohepatitis 
Yoshihisa Takahashi, Keiichiro Sugimoto, Hiroshi Inui, Toshio Fukusato 
World J Gastroenterol 21(13):3777-3785. Published online Apr 7, 2015. doi: 10.3748/wjg.v21.i13.3777
Topic Highlight
Hepatitis C virus and antiviral innate immunity: Who wins at tug-of-war? 
Da-Rong Yang, Hai-Zhen Zhu 
World J Gastroenterol 21(13):3786-3800. Published online Apr 7, 2015. doi: 10.3748/wjg.v21.i13.3786
Review
Gastrointestinal Behçet's disease: A review 
Wasseem Skef, Matthew J Hamilton, Thurayya Arayssi 
World J Gastroenterol 21(13):3801-3812. Published online Apr 7, 2015. doi: 10.3748/wjg.v21.i13.3801
New gene therapy strategies for hepatic fibrosis 
Adriana M Salazar-Montes, Luis D Hernández-Ortega, Martha S Lucano-Landeros, Juan Armendariz-Borunda 
World J Gastroenterol 21(13):3813-3825. Published online Apr 7, 2015. doi: 10.3748/wjg.v21.i13.3813
Current management of hepatocellular carcinoma: An Eastern perspective 
Hyung Joon Yim, Sang Jun Suh, Soon Ho Um 
World J Gastroenterol 21(13):3826-3842. Published online Apr 7, 2015. doi: 10.3748/wjg.v21.i13.3826
Hepatic artery infusion chemotherapy for advanced hepatocellular carcinoma 
Myeong Jun Song 
World J Gastroenterol 21(13):3843-3849. Published online Apr 7, 2015. doi: 10.3748/wjg.v21.i13.3843
Minireviews
Adjuvant therapy for gastric cancer: What have we learned since INT0116? 
Alexandre A Jácome, Ajith K Sankarankutty, José Sebastião dos Santos 
World J Gastroenterol 21(13):3850-3859. Published online Apr 7, 2015. doi: 10.3748/wjg.v21.i13.3850
Antiviral therapies for hepatitis B virus-related hepatocellular carcinoma 
Yuan-Qing Zhang, Jin-Sheng Guo 
World J Gastroenterol 21(13):3860-3866. Published online Apr 7, 2015. doi: 10.3748/wjg.v21.i13.3860
Basic Study
Insulin-like growth factor-1 mRNA isoforms and insulin-like growth factor-1 receptor mRNA expression in chronic hepatitis C 
Aldona Kasprzak, Agnieszka Adamek, Wiesława Przybyszewska, Przemysław Pyda, Jacek Szmeja, Agnieszka Seraszek-Jaros, Agata Lanzafame, Anna Surdacka, Iwona Mozer-Lisewska, Maria Koczorowska 
World J Gastroenterol 21(13):3867-3875. Published online Apr 7, 2015. doi: 10.3748/wjg.v21.i13.3867
Fucosylation is a common glycosylation type in pancreatic cancer stem cell-like phenotypes 
Naoko Terao, Shinji Takamatsu, Tomomi Minehira, Tomoaki Sobajima, Kotarosumitomo Nakayama, Yoshihiro Kamada, Eiji Miyoshi 
World J Gastroenterol 21(13):3876-3887. Published online Apr 7, 2015. doi: 10.3748/wjg.v21.i13.3876
Esophageal variceal pressure influence on the effect of ligation 
Zhi-Qun Li, En-Qiang LingHu, Min Hu, Wei-Min Li, Qi-Yang Huang, Yong-Wei Zhao 
World J Gastroenterol 21(13):3888-3892. Published online Apr 7, 2015. doi: 10.3748/wjg.v21.i13.3888
Caffeic acid phenethyl ester inhibits liver fibrosis in rats 
Mei Li, Xiu-Fang Wang, Juan-Juan Shi, Ya-Ping Li, Ning Yang, Song Zhai, Shuang-Suo Dang 
World J Gastroenterol 21(13):3893-3903. Published online Apr 7, 2015. doi: 10.3748/wjg.v21.i13.3893
Case Control Study
Interferon-λ3 polymorphisms in pegylated-interferon-α plus ribavirin therapy for genotype-2 chronic hepatitis C 
Haruya Ishiguro, Hiroshi Abe, Nobuyoshi Seki, Tomonori Sugita, Yuta Aida, Munenori Itagaki, Satoshi Sutoh, Noritomo Shimada, Tomomi Furihata, Akihito Tsubota, Yoshio Aizawa 
World J Gastroenterol 21(13):3904-3911. Published online Apr 7, 2015. doi: 10.3748/wjg.v21.i13.3904
Retrospective Cohort Study
Hepatitis C virus recurrence after liver transplantation: A 10-year evaluation 
Stefano Gitto, Luca Saverio Belli, Ranka Vukotic, Stefania Lorenzini, Aldo Airoldi, Arrigo Francesco Giuseppe Cicero, Marcello Vangeli, Lucia Brodosi, Arianna Martello Panno, Roberto Di Donato, Matteo Cescon, Gian Luca Grazi, Luciano De Carlis, Antonio Daniele Pinna, Mauro Bernardi, Pietro Andreone 
World J Gastroenterol 21(13):3912-3920. Published online Apr 7, 2015. doi: 10.3748/wjg.v21.i13.3912
Clinical and computed tomography findings of appendiceal diverticulitis vs acute appendicitis 
Daisuke Ito, Kenji Miki, Shimizu Seiichiro, Shojiro Hata, Kaoru Kobayashi, Masanori Teruya, Michio Kaminishi 
World J Gastroenterol 21(13):3921-3927. Published online Apr 7, 2015. doi: 10.3748/wjg.v21.i13.3921
Retrospective Study
Diagnostic value of PIVKA-II and alpha-fetoprotein in hepatitis B virus-associated hepatocellular carcinoma 
Seung In Seo, Hyoung Su Kim, Won Jin Kim, Woon Geon Shin, Doo Jin Kim, Kyung Ho Kim, Myoung Kuk Jang, Jin Heon Lee, Joo Seop Kim, Hak Yang Kim, Dong Joon Kim, Myung Seok Lee, Choong Kee Park 
World J Gastroenterol 21(13):3928-3935. Published online Apr 7, 2015. doi: 10.3748/wjg.v21.i13.3928
Eradication rate and histological changes after Helicobacter pylori eradication treatment in gastric cancer patients following subtotal gastrectomy 
Jae Jin Hwang, Dong Ho Lee, Kyu Keun Kang, Ae-Ra Lee, Hyuk Yoon, Cheol Min Shin, Young Soo Park, Nayoung Kim 
World J Gastroenterol 21(13):3936-3943. Published online Apr 7, 2015. doi: 10.3748/wjg.v21.i13.3936
Is endoscopic submucosal dissection safe for papillary adenocarcinoma of the stomach? 
Hyun Jeong Lee, Gwang Ha Kim, Do Youn Park, Bong Eun Lee, Hye Kyung Jeon, Joon Hyung Jhi, Geun Am Song 
World J Gastroenterol 21(13):3944-3952. Published online Apr 7, 2015. doi: 10.3748/wjg.v21.i13.3944
Differentiation of acute and chronic hepatitis B in IgM anti-HBc positive patients 
Ji Won Park, Kyeong Min Kwak, Sung Eun Kim, Myoung Kuk Jang, Dong Joon Kim, Myung Seok Lee, Hyoung Su Kim, Choong Kee Park 
World J Gastroenterol 21(13):3953-3959. Published online Apr 7, 2015. doi: 10.3748/wjg.v21.i13.3953
Methylation of IRAK3 is a novel prognostic marker in hepatocellular carcinoma 
Chih-Chi Kuo, Yu-Lueng Shih, Her-Young Su, Ming-De Yan, Chung-Bao Hsieh, Chin-Yu Liu, Wei-Ting Huang, Mu-Hsien Yu, Ya-Wen Lin 
World J Gastroenterol 21(13):3960-3969. Published online Apr 7, 2015. doi: 10.3748/wjg.v21.i13.3960
Oxaliplatin and 5-fluorouracil hepatic infusion with lipiodolized chemoembolization in large hepatocellular carcinoma 
Jing-Huan Li, Xiao-Ying Xie, Lan Zhang, Fan Le, Ning-Ling Ge, Li-Xin Li, Yu-Hong Gan, Yi Chen, Ju-Bo Zhang, Tong-Chun Xue, Rong-Xin Chen, Jing-Lin Xia, Bo-Heng Zhang, Sheng-Long Ye, Yan-Hong Wang, Zheng-Gang Ren 
World J Gastroenterol 21(13):3970-3977. Published online Apr 7, 2015. doi: 10.3748/wjg.v21.i13.3970
Endoscopic transpancreatic septotomy as a precutting technique for difficult bile duct cannulation 
Lin Miao, Quan-Peng Li, Ming-Hui Zhu, Xian-Xiu Ge, Hong Yu, Fei Wang, Guo-Zhong Ji 
World J Gastroenterol 21(13):3978-3982. Published online Apr 7, 2015. doi: 10.3748/wjg.v21.i13.3978
Clinical Trials Study
Decreased STAT4 indicates poor prognosis and enhanced cell proliferation in hepatocellular carcinoma 
Gang Wang, Jia-Hui Chen, Yong Qiang, Dong-Zhi Wang, Zhong Chen 
World J Gastroenterol 21(13):3983-3993. Published online Apr 7, 2015. doi: 10.3748/wjg.v21.i13.3983
Observational Study
Importance of reporting segmental bowel preparation scores during colonoscopy in clinical practice 
Deepanshu Jain, Mojdeh Momeni, Mahesh Krishnaiah, Sury Anand, Shashideep Singhal 
World J Gastroenterol 21(13):3994-3999. Published online Apr 7, 2015. doi: 10.3748/wjg.v21.i13.3994
Rectal tone and compliance affected in patients with fecal incontinence after fistulotomy 
Richard Alexander Awad, Santiago Camacho, Francisco Flores, Evelyn Altamirano, Mario Antonio García 
World J Gastroenterol 21(13):4000-4005. Published online Apr 7, 2015. doi: 10.3748/wjg.v21.i13.4000
Interferon-λ-related genes and therapeutic response in Chinese hepatitis C patients 
Yuan-Yuan Zhang, Hong-Bo Chen, Yin Xu, Peng Huang, Jie Wang, Yun Zhang, Rong-Bin Yu, Jing Su 
World J Gastroenterol 21(13):4006-4013. Published online Apr 7, 2015. doi: 10.3748/wjg.v21.i13.4006
Prospective Study
Endoscopic ultrasound elastography strain histograms in the evaluation of patients with pancreatic masses 
Dalibor Opačić, Nadan Rustemović, Mirjana Kalauz, Pave Markoš, Zvonimir Ostojić, Matea Majerović, Iva Ledinsky, Ana Višnjić, Juraj Krznarić, Milorad Opačić 
World J Gastroenterol 21(13):4014-4019. Published online Apr 7, 2015. doi: 10.3748/wjg.v21.i13.4014
PERFACT procedure: A new concept to treat highly complex anal fistula 
Pankaj Garg, Mahak Garg 
World J Gastroenterol 21(13):4020-4029. Published online Apr 7, 2015. doi: 10.3748/wjg.v21.i13.4020
Lower gastrointestinal bleeding: Role of 64-row computed tomographic angiography in diagnosis and therapeutic planning 
Jian-Zhuang Ren, Meng-Fan Zhang, Ai-Mei Rong, Xiang-Jie Fang, Kai Zhang, Guo-Hao Huang, Peng-Fei Chen, Zhao-Yang Wang, Xu-Hua Duan, Xin-Wei Han, Yan-Jie Liu 
World J Gastroenterol 21(13):4030-4037. Published online Apr 7, 2015. doi: 10.3748/wjg.v21.i13.4030
Meta-Analysis
Osteoporosis and bone fractures in alcoholic liver disease: A meta-analysis 
Chang Seok Bang, In Soo Shin, Sung Wha Lee, Jin Bong Kim, Gwang Ho Baik, Ki Tae Suk, Jai Hoon Yoon, Yeon Soo Kim, Dong Joon Kim 
World J Gastroenterol 21(13):4038-4047. Published online Apr 7, 2015. doi: 10.3748/wjg.v21.i13.4038
Case Report
Resolution of Crohn's disease and complex regional pain syndrome following treatment of paratuberculosis 
J Todd Kuenstner, William Chamberlin, Saleh A Naser, Michael T Collins, Coad Thomas Dow, John M Aitken, Stuart Weg, Grzegorz Telega, Kuruvilla John, David Haas, Torsten M Eckstein, Maher Kali, Christine Welch, Thomas Petrie 
World J Gastroenterol 21(13):4048-4062. Published online Apr 7, 2015. doi: 10.3748/wjg.v21.i13.4048
Urea cycle disorders: A case report of a successful treatment with liver transplant and a literature review 
Francesco Giuseppe Foschi, Maria Cristina Morelli, Sara Savini, Anna Chiara Dall’Aglio, Arianna Lanzi, Matteo Cescon, Giorgio Ercolani, Alessandro Cucchetti, Antonio Daniele Pinna, Giuseppe Francesco Stefanini 
World J Gastroenterol 21(13):4063-4068. Published online Apr 7, 2015. doi: 10.3748/wjg.v21.i13.4063
Gastroenterology case report of mesalazine-induced cardiopulmonary hypersensitivity 
José Ferrusquía, Isabel Pérez-Martínez, Ricardo Gómez de la Torre, María Luisa Fernández-Almira, Ruth de Francisco, Luis Rodrigo, Sabino Riestra 
World J Gastroenterol 21(13):4069-4077. Published online Apr 7, 2015. doi: 10.3748/wjg.v21.i13.4069
Treatment of Crohn’s disease and familial Mediterranean fever by leukopheresis: Single shot for two targets 
Mahmut Yuksel, Fatih Saygili, Orhan Coskun, Nuretdin Suna, Mustafa Kaplan, Ufuk Baris Kuzu, Zeki Mesut Yalin Kilic, Yasemin Ozderin Ozin, Ertugrul Kayacetin 
World J Gastroenterol 21(13):4078-4081. Published online Apr 7, 2015. doi: 10.3748/wjg.v21.i13.4078
Adenocarcinoma arising from heterotopic pancreas at the third portion of the duodenum 
Nobutada Fukino, Takatsugu Oida, Kenji Mimatsu, Youichi Kuboi, Kazutoshi Kida 
World J Gastroenterol 21(13):4082-4088. Published online Apr 7, 2015. doi: 10.3748/wjg.v21.i13.4082
Lymphoepithelioma-like cholangiocarcinoma: A mimic of hepatocellular carcinoma on imaging features 
Tsan-Chieh Liao, Chien-An Liu, Nai-Chi Chiu, Yi-Chen Yeh, Yi-You Chiou 
World J Gastroenterol 21(13):4089-4095. Published online Apr 7, 2015. doi: 10.3748/wjg.v21.i13.4089
Segmental small bowel necrosis associated with antiphospholipid syndrome: A case report 
Qun-Ying Wang, Xiao-Hua Ye, Jin Ding, Xiao-Kang Wu 
World J Gastroenterol 21(13):4096-4100. Published online Apr 7, 2015. doi: 10.3748/wjg.v21.i13.4096
Letters To The Editor
Lower folate levels in gastric cancer: Is it a cause or a result? 
Ali Alkan, Dılşa Mızrak, Güngör Utkan 
World J Gastroenterol 21(13):4101-4102. Published online Apr 7, 2015. doi: 10.3748/wjg.v21.i13.4101