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©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Mar 28, 2015; 21(12): 3599-3606
Published online Mar 28, 2015. doi: 10.3748/wjg.v21.i12.3599
Published online Mar 28, 2015. doi: 10.3748/wjg.v21.i12.3599
Poor prognosis for hepatocellular carcinoma with transarterial chemoembolization pre-transplantation: Retrospective analysis
Hai-Lin Li, Rui Zhao, Department of Hepatobiliary Surgery, Qilu Hospital, Shandong University, Jinan 250012, Shandong Province, China
Wen-Bin Ji, Wei-Dong Duan, Yong-Wei Chen, Xian-Qiang Wang, Qiang Yu, Ying Luo, Jia-Hong Dong, Hospital and Institute of Hepatobiliary Surgery, Chinese PLA General Hospital, Beijing 100853, China
Author contributions: Li HL and Dong JH designed research; Li HL, Dong JH, Ji WB, Duan WD, Chen YW, Yu Q and Luo Y performed research; Li HL, Ji WB, Duan WD, Zhao R, Wang XQ, Yu Q and Luo Y contributed analytical tools; Li HL and Ji WB analyzed data; and Li HL wrote the paper.
Supported by National Science and Technology Major Project for Infectious Diseases of China, No. 2012ZX10002-017; National Key Technology Research And Development Program of China, No. 2012BAI06B01; and the Grants from Natural Science Foundation of China, No. 81302123.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Jia-Hong Dong, MD, PhD, FACS, Hospital and Institute of Hepatobiliary Surgery, Chinese PLA General Hospital, 28 Fuxing Road, Haidian District, Beijing 100853, China. dongjh301@163.com
Telephone: +86-10-66938030 Fax: +86-10-68241383
Received: July 13, 2014
Peer-review started: July 13, 2014
First decision: August 15, 2014
Revised: September 30, 2014
Accepted: October 21, 2014
Article in press: October 21, 2014
Published online: March 28, 2015
Peer-review started: July 13, 2014
First decision: August 15, 2014
Revised: September 30, 2014
Accepted: October 21, 2014
Article in press: October 21, 2014
Published online: March 28, 2015
Core Tip
Core tip: Hepatocellular carcinoma (HCC) has a high prevalence in China. Patients always have a long-term history of liver cirrhosis, varying degrees of portal hypertension symptoms, and the tumor volume exceeds the Milan criteria when they receive treatment. Whether it is necessary to adopt transarterial chemoembolization (TACE), which is more commonly used in China pre-transplantation, when the patients in waiting state. This study assessed the influence of preoperative TACE on long-term survival in liver transplantation (LT). TACE pre-LT in patients with HCC increased the chances of pulmonary or distant metastasis of the primary tumor, thus reducing long-term survival.