Welcome to World Journal of Gastrointestinal Pathophysiology


The World Journal of Gastrointestinal Pathophysiology (WJGP) is a leading academic journal devoted to reporting the latest, cutting-edge research progress and findings of basic research and clinical practice in the field of gastrointestinal pathophysiology.  It was launched on April 15, 2010 and is published trimonthly (4 issues annually) by BPG, the world's leading professional clinical medical journal publishing company.


We encourage gastrointestinal pathophysiologists worldwide to submit manuscripts to the WJGP describing their original basic or clinical research findings that are of high academic value and which report new diagnostic techniques or summarize their treatment experiences.


The usual times related to all publication processes of the WJGP are as follows: (1) From manuscript receipt to peer-review: 2-4 weeks; (2) From initial manuscript acceptance, with revisions, to return of the revised manuscript from the authors: 4-5 weeks; (3) From return of the revised manuscript from the authors to final acceptance: 1-2 weeks; (4) From final acceptance to an article in press: 2 days; and (5) From article in press designation to formal release of the electronic version and all online documentation: 2-9 weeks. The WJGP’s acceptance rate: 56%.  Submit here >>

Published Issues

Thomas Ma, MD, PhD, Professor; Timothy Pawlik, MD, Director, Professor


PubMed, PubMed Central.

Impact Factor

There is currently no impact factor.


2150-5330 (online)

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Contents Volume 7  Issue 1  February 15, 2016
Mucosal healing in inflammatory bowel disease: Maintain or de-escalate therapy  
Marcello Cintolo, Giuseppe Costantino, Socrate Pallio, Walter Fries
World J Gastrointest Pathophysiol 7(1):1-16. Published online Feb 15, 2016. doi: 10.4291/wjgp.v7.i1.1
Adipose tissue-liver axis in alcoholic liver disease  
Zhi-Gang Wang, Xiao-Bing Dou, Zhan-Xiang Zhou, Zhen-Yuan Song
World J Gastrointest Pathophysiol 7(1):17-26. Published online Feb 15, 2016. doi: 10.4291/wjgp.v7.i1.17
Diagnostic Advances
Current application of proteomics in biomarker discovery for inflammatory bowel disease  
Patrick PY Chan, Valerie C Wasinger, Rupert W Leong
World J Gastrointest Pathophysiol 7(1):27-37. Published online Feb 15, 2016. doi: 10.4291/wjgp.v7.i1.27
Amniotic fluid: Source of trophic factors for the developing intestine  
Soham Dasgupta, Shreyas Arya, Sanjeev Choudhary, Sunil K Jain
World J Gastrointest Pathophysiol 7(1):38-47. Published online Feb 15, 2016. doi: 10.4291/wjgp.v7.i1.38
Alcoholic pancreatitis: New insights into the pathogenesis and treatment  
Dahn L Clemens, Katrina J Schneider, Christopher K Arkfeld, Jaclyn R Grode, Mark A Wells, Shailender Singh
World J Gastrointest Pathophysiol 7(1):48-58. Published online Feb 15, 2016. doi: 10.4291/wjgp.v7.i1.48
Faecal incontinence: Current knowledges and perspectives  
Alban Benezech, Michel Bouvier, Véronique Vitton
World J Gastrointest Pathophysiol 7(1):59-71. Published online Feb 15, 2016. doi: 10.4291/wjgp.v7.i1.59
Esophageal testing: What we have so far  
Nicola de Bortoli, Irene Martinucci, Lorenzo Bertani, Salvatore Russo, Riccardo Franchi, Manuele Furnari, Salvatore Tolone, Giorgia Bodini, Valeria Bolognesi, Massimo Bellini, Vincenzo Savarino, Santino Marchi, Edoardo Vincenzo Savarino
World J Gastrointest Pathophysiol 7(1):72-85. Published online Feb 15, 2016. doi: 10.4291/wjgp.v7.i1.72
Upper gastrointestinal bleeding risk scores: Who, when and why?  
Sara Monteiro, Tiago Cúrdia Gonçalves, Joana Magalhães, José Cotter
World J Gastrointest Pathophysiol 7(1):86-96. Published online Feb 15, 2016. doi: 10.4291/wjgp.v7.i1.86
Role of Helicobacter pylori infection in pathogenesis of gastric carcinoma  
Rong-Guang Zhang, Guang-Cai Duan, Qing-Tang Fan, Shuai-Yin Chen
World J Gastrointest Pathophysiol 7(1):97-107. Published online Feb 15, 2016. doi: 10.4291/wjgp.v7.i1.97
Mechanisms of interleukin-22’s beneficial effects in acute pancreatitis  
Chongmin Huan, Daniel Kim, Peiqi Ou, Antonio Alfonso, Albert Stanek
World J Gastrointest Pathophysiol 7(1):108-116. Published online Feb 15, 2016. doi: 10.4291/wjgp.v7.i1.108
Small bowel neuroendocrine tumors: From pathophysiology to clinical approach  
Sofia Xavier, Bruno Rosa, José Cotter
World J Gastrointest Pathophysiol 7(1):117-124. Published online Feb 15, 2016. doi: 10.4291/wjgp.v7.i1.117
Mesenteric ischemia: Pathogenesis and challenging diagnostic and therapeutic modalities  
Aikaterini Mastoraki, Sotiria Mastoraki, Evgenia Tziava, Stavroula Touloumi, Nikolaos Krinos, Nikolaos Danias, Andreas Lazaris, Nikolaos Arkadopoulos
World J Gastrointest Pathophysiol 7(1):125-130. Published online Feb 15, 2016. doi: 10.4291/wjgp.v7.i1.125
Role of nitric oxide in the pathogenesis of Barrett’s-associated carcinogenesis  
Gen Kusaka, Kaname Uno, Katsunori Iijima, Tooru Shimosegawa
World J Gastrointest Pathophysiol 7(1):131-137. Published online Feb 15, 2016. doi: 10.4291/wjgp.v7.i1.131
Basic Study
Differential expression of pancreatic protein and chemosensing receptor mRNAs in NKCC1-null intestine  
Emily M Bradford, Kanimozhi Vairamani, Gary E Shull
World J Gastrointest Pathophysiol 7(1):138-149. Published online Feb 15, 2016. doi: 10.4291/wjgp.v7.i1.138
Neurophysiological mechanisms of bradykinin-evoked mucosal chloride secretion in guinea pig small intestine  
Mei-Hua Qu, Wan-Sheng Ji, Ting-Kun Zhao, Chun-Yan Fang, Shu-Mei Mao, Zhi-Qin Gao
World J Gastrointest Pathophysiol 7(1):150-159. Published online Feb 15, 2016. doi: 10.4291/wjgp.v7.i1.150
Clinical Trials Study
Hypoallergenic formula with Lactobacillus rhamnosus GG for babies with colic: A pilot study of recruitment, retention, and fecal biomarkers  
Nicole Y Fatheree, Yuying Liu, Michael Ferris, Melissa Van Arsdall, Valarie McMurtry, Marcela Zozaya, Chunyan Cai, Mohammad H Rahbar, Manouchehr Hessabi, Ta Vu, Christine Wong, Juleen Min, Dat Q Tran, Fernando Navarro, Wallace Gleason, Sara Gonzalez, J Marc Rhoads
World J Gastrointest Pathophysiol 7(1):160-170. Published online Feb 15, 2016. doi: 10.4291/wjgp.v7.i1.160
Observational Study
Efficacy and tolerability of hydrogen carbonate-rich water for heartburn  
André-Michael Beer, Ralf Uebelhack, Ute Pohl
World J Gastrointest Pathophysiol 7(1):171-180. Published online Feb 15, 2016. doi: 10.4291/wjgp.v7.i1.171
Prospective Study
High rate of Helicobacter pylori reinfection in Lithuanian peptic ulcer patients  
Laimas Jonaitis, Gediminas Kiudelis, Paulius Slepavicius, Limas Kupcinskas
World J Gastrointest Pathophysiol 7(1):181-185. Published online Feb 15, 2016. doi: 10.4291/wjgp.v7.i1.181
Systematic Reviews
Intra-abdominal pressure: Time ripe to revise management guidelines of acute pancreatitis?  
Jiten Jaipuria, Vimal Bhandari, Avneet Singh Chawla, Mohit Singh
World J Gastrointest Pathophysiol 7(1):186-198. Published online Feb 15, 2016. doi: 10.4291/wjgp.v7.i1.186