MicroRNA-1290 promotes esophageal squamous cell carcinoma cell proliferation and metastasis

doi:10.3748/wjg.v21.i11.3245

Advanced Search

BPG is committed to discovery and dissemination of knowledge

Home / Archive / Volume 21, Issue 11

This Article

Academic Content and Language Evaluation of This Article

CrossCheck and Google Search of This Article

Academic Rules and Norms of This Article

Citation of this article

Corresponding Author of This Article

Research Domain of This Article

Article-Type of This Article

Open-Access Policy of This Article

Times Cited Counts in Google of This Article

Number of Hits and Downloads for This Article

Total Article Views (7303)

All Articles published online

The chart showing PDF series, WORD series, HTML series, Figures (1-6) series, Tables (1-1) series.

Item

Count

PDF

420

WORD

267

HTML

3495

Figures (1-6)

194

Tables (1-1)

153

Sum=4529

Publishing Process of This Article

The chart showing Browse series, Download series.

Item

Count

Browse

1222

Download

1552

Sum=2774

Mar 21, 2015 (publication date) through Apr 18, 2024

Times Cited of This Article

Times Cited (38)

Journal Information of This Article

Publication Name

World Journal of Gastroenterology

ISSN

1007-9327

Publisher of This Article

Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Basic Study

World J Gastroenterol. Mar 21, 2015; 21(11): 3245-3255
Published online Mar 21, 2015. doi: 10.3748/wjg.v21.i11.3245

MicroRNA-1290 promotes esophageal squamous cell carcinoma cell proliferation and metastasis

Ming Li, Xiao-Yan He, Zhi-Mei Zhang, Shuo Li, Li-Hua Ren, Ri-Sheng Cao, Ya-Dong Feng, Yin-Lin Ji, Ye Zhao, Rui-Hua Shi

Ming Li, Xiao-Yan He, Zhi-Mei Zhang, Shuo Li, Li-Hua Ren, Ri-Sheng Cao, Ya-Dong Feng, Yin-Lin Ji, Ye Zhao, Rui-Hua Shi, Department of Gastroenterology, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210009, Jiangsu Province, China

Ming Li, Department of Gastroenterology, Friendliness Hospital of Yangzhou, Yangzhou 225009, Jiangsu Province, China

Zhi-Mei Zhang, Department of Gastroenterology, First People’s Hospital of Lianyunina, Lianyunina 222002, Jiangsu Province, China

Author contributions: Li M designed the research; He XY, Zhang ZM, Li S and Ren LH performed the research; Cao RS and Feng YD collected the clinical data; Ji YL, Shi RH and Zhao Y analyzed the data; and Li M wrote the paper.

Supported by grants from Innovative Team Project of Jiangsu Province, China, No. CXZZ11_0705.

Corresponding author: Rui-Hua Shi, MD, PhD, Department of Gastroenterology, The First Affiliated Hospital of Nanjing Medical University, No. 300 Guang Zhou Road, Gulou District, Nanjing 210029, Jiangsu Province. China. ruihuashi@126.com

Received: August 8, 2014
Revised: October 11, 2014
Accepted: December 14, 2014
Published online: March 21, 2015

Core Tip

Core Tip: In this study, we reported the clinical significance and biological effects of miR-1290 in esophageal squamous cell carcinoma (ESCC). We found that miR-1290 was significantly up-regulated in ESCC tissues. Moreover, we showed that ectopic expression of miR-1290 significantly promoted ESCC cell growth, migration and invasion. Further investigation revealed that suppressor of cancer cell invasion was a downstream target of miR-1290.