Published online Mar 21, 2015. doi: 10.3748/wjg.v21.i11.3388
Peer-review started: July 27, 2014
First decision: September 15, 2014
Revised: October 18, 2014
Accepted: December 16, 2014
Article in press: December 16, 2014
Published online: March 21, 2015
Core tip: This is a detailed case study of a 52-year-old male patient treated for very uncommon histological subtype of gastric gastrointestinal stromal tumour (GIST) with atypical clinical presentation, asymptomatic progress and late diagnosis. The resected tumour, giant in diameters, was confirmed to represent the most rare histopathologic subtype of GISTs - sarcomatoid epithelioid GIST. We report this case and review the literature with a special focus on pathomorphological evaluation, biological aggressiveness and prognostic factors. To our knowledge this is the first report of giant GIST of very uncommon sarcomatoid epithelioid subtype.