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Topic Highlight
Microbiota and the gut-liver axis: Bacterial translocation, inflammation and infection in cirrhosis 
Valerio Giannelli, Vincenza Di Gregorio, Valerio Iebba, Michela Giusto, Serena Schippa, Manuela Merli, Ulrich Thalheimer 
World J Gastroenterol 20(45):16795-16810. Published online Dec 7, 2014. doi: 10.3748/wjg.v20.i45.16795
Noninvasive assessment of portal hypertension in cirrhosis: Liver stiffness and beyond 
Horia Stefanescu, Bogdan Procopet 
World J Gastroenterol 20(45):16811-16819. Published online Dec 7, 2014. doi: 10.3748/wjg.v20.i45.16811
Non-invasive diagnosis of advanced fibrosis and cirrhosis 
Suraj Sharma, Korosh Khalili, Geoffrey Christopher Nguyen 
World J Gastroenterol 20(45):16820-16830. Published online Dec 7, 2014. doi: 10.3748/wjg.v20.i45.16820
Alimentary regimen in non-alcoholic fatty liver disease: Mediterranean diet 
Ludovico Abenavoli, Natasa Milic, Valentina Peta, Francesco Alfieri, Antonino De Lorenzo, Stefano Bellentani 
World J Gastroenterol 20(45):16831-16840. Published online Dec 7, 2014. doi: 10.3748/wjg.v20.i45.16831
Focus on emerging drugs for the treatment of patients with non-alcoholic fatty liver disease 
Alessandro Federico, Claudio Zulli, Ilario de Sio, Anna Del Prete, Marcello Dallio, Mario Masarone, Carmela Loguercio 
World J Gastroenterol 20(45):16841-16857. Published online Dec 7, 2014. doi: 10.3748/wjg.v20.i45.16841
Computed tomography colonography in 2014: An update on technique and indications 
Andrea Laghi 
World J Gastroenterol 20(45):16858-16867. Published online Dec 7, 2014. doi: 10.3748/wjg.v20.i45.16858
Pharmacologic therapy for acute pancreatitis 
Swetha Kambhampati, Walter Park, Aida Habtezion 
World J Gastroenterol 20(45):16868-16880. Published online Dec 7, 2014. doi: 10.3748/wjg.v20.i45.16868
Autoimmune pancreatitis: Multimodality non-invasive imaging diagnosis 
Stefano Crosara, Mirko D'Onofrio, Riccardo De Robertis, Emanuele Demozzi, Stefano Canestrini, Giulia Zamboni, Roberto Pozzi Mucelli 
World J Gastroenterol 20(45):16881-16890. Published online Dec 7, 2014. doi: 10.3748/wjg.v20.i45.16881
Acute recurrent pancreatitis: Etiopathogenesis, diagnosis and treatment 
Pier Alberto Testoni 
World J Gastroenterol 20(45):16891-16901. Published online Dec 7, 2014. doi: 10.3748/wjg.v20.i45.16891
Hormonal protection in acute pancreatitis by ghrelin, leptin and melatonin 
Jolanta Jaworek, Stanisław Jan Konturek 
World J Gastroenterol 20(45):16902-16912. Published online Dec 7, 2014. doi: 10.3748/wjg.v20.i45.16902
Balloon dilation itself may not be a major determinant of post-endoscopic retrograde cholangiopancreatography pancreatitis 
Sung Ill Jang, Gak Won Yun, Dong Ki Lee 
World J Gastroenterol 20(45):16913-16924. Published online Dec 7, 2014. doi: 10.3748/wjg.v20.i45.16913
Is necrosectomy obsolete for infected necrotizing pancreatitis? Is a paradigm shift needed? 
Yu-Chung Chang 
World J Gastroenterol 20(45):16925-16934. Published online Dec 7, 2014. doi: 10.3748/wjg.v20.i45.16925
Immunomodulatory therapies for acute pancreatitis 
Jing Li, Wen-Juan Yang, Lu-Ming Huang, Cheng-Wei Tang 
World J Gastroenterol 20(45):16935-16947. Published online Dec 7, 2014. doi: 10.3748/wjg.v20.i45.16935
Colon capsule endoscopy: What we know and what we would like to know 
Cristiano Spada, Federico Barbaro, Gianluca Andrisani, Leonardo Minelli Grazioli, Cesare Hassan, Isabella Costamagna, Mariachiara Campanale, Guido Costamagna 
World J Gastroenterol 20(45):16948-16955. Published online Dec 7, 2014. doi: 10.3748/wjg.v20.i45.16948
Systematic review of emergent laparoscopic colorectal surgery for benign and malignant disease 
Manish Chand, Muhammed RS Siddiqui, Ashish Gupta, Shahnawaz Rasheed, Paris Tekkis, Amjad Parvaiz, Alex H Mirnezami, Tahseen Qureshi 
World J Gastroenterol 20(45):16956-16963. Published online Dec 7, 2014. doi: 10.3748/wjg.v20.i45.16956
Preoperative evaluation of colorectal cancer using CT colonography, MRI, and PET/CT 
Shigeyoshi Kijima, Takahiro Sasaki, Koichi Nagata, Kenichi Utano, Alan T Lefor, Hideharu Sugimoto 
World J Gastroenterol 20(45):16964-16975. Published online Dec 7, 2014. doi: 10.3748/wjg.v20.i45.16964
Hemorrhoidectomy - making sense of the surgical options 
Danson Yeo, Kok-Yang Tan 
World J Gastroenterol 20(45):16976-16983. Published online Dec 7, 2014. doi: 10.3748/wjg.v20.i45.16976
Review
Colonoscopy procedural skills and training for new beginners 
Seung-Hwa Lee, Young-Kyu Park, Duck-Joo Lee, Kwang-Min Kim 
World J Gastroenterol 20(45):16984-16995. Published online Dec 7, 2014. doi: 10.3748/wjg.v20.i45.16984
Transjugular intrahepatic portosystemic shunts and portal hypertension-related complications 
Sith Siramolpiwat 
World J Gastroenterol 20(45):16996-17010. Published online Dec 7, 2014. doi: 10.3748/wjg.v20.i45.16996
MicroRNAs in colorectal cancer: Role in metastasis and clinical perspectives 
Shan Muhammad, Kavanjit Kaur, Rui Huang, Qian Zhang, Paviter Kaur, Hamza Obaid Yazdani, Muhammad Umar Bilal, Jiang Zheng, Liu Zheng, Xi-Shan Wang 
World J Gastroenterol 20(45):17011-17019. Published online Dec 7, 2014. doi: 10.3748/wjg.v20.i45.17011
Efficacy and safety of herbal medicines in treating gastric ulcer: A review 
Wei-Ping Bi, Hui-Bin Man, Mao-Qiang Man 
World J Gastroenterol 20(45):17020-17028. Published online Dec 7, 2014. doi: 10.3748/wjg.v20.i45.17020
Minireviews
Chemopreventive effect of apple and berry fruits against colon cancer 
Saravana Kumar Jaganathan, Muthu Vignesh Vellayappan, Gayathri Narasimhan, Eko Supriyanto, Dyah Ekashanti Octorina Dewi, Aqilah Leela T Narayanan, Arunpandian Balaji, Aruna Priyadarshini Subramanian, Mustafa Yusof 
World J Gastroenterol 20(45):17029-17036. Published online Dec 7, 2014. doi: 10.3748/wjg.v20.i45.17029
Original Article
Up-regulation of mitochondrial chaperone TRAP1 in ulcerative colitis associated colorectal cancer 
Ru Chen, Sheng Pan, Keith Lai, Lisa A Lai, David A Crispin, Mary P Bronner, Teresa A Brentnall 
World J Gastroenterol 20(45):17037-17048. Published online Dec 7, 2014. doi: 10.3748/wjg.v20.i45.17037
CYLD deletion triggers nuclear factor-κB-signaling and increases cell death resistance in murine hepatocytes 
Toni Urbanik, Bruno Christian Koehler, Laura Wolpert, Christin Elßner, Anna-Lena Scherr, Thomas Longerich, Nicole Kautz, Stefan Welte, Nadine Hövelmeyer, Dirk Jäger, Ari Waisman, Henning Schulze-Bergkamen 
World J Gastroenterol 20(45):17049-17064. Published online Dec 7, 2014. doi: 10.3748/wjg.v20.i45.17049
Correlation between hepatic blood flow and liver function in alcoholic liver cirrhosis 
Hideaki Takahashi, Ryuta Shigefuku, Yoshihito Yoshida, Hiroki Ikeda, Kotaro Matsunaga, Nobuyuki Matsumoto, Chiaki Okuse, Shigeru Sase, Fumio Itoh, Michihiro Suzuki 
World J Gastroenterol 20(45):17065-17074. Published online Dec 7, 2014. doi: 10.3748/wjg.v20.i45.17065
Research Report
Applicability and efficacy of a model for prevention of perinatal transmission of hepatitis B virus infection: Single center study in Egypt 
Hanaa M El-Karaksy, Lamiaa M Mohsen, Doa’a A Saleh, Mona S Hamdy, Noha A Yassin, Mohamed Farouk, Mohamed E Salit, Mortada H El-Shabrawi 
World J Gastroenterol 20(45):17075-17083. Published online Dec 7, 2014. doi: 10.3748/wjg.v20.i45.17075
Clostridium difficile infection aggravates colitis in interleukin 10-deficient mice 
Mi Na Kim, Seong-Joon Koh, Jung Mogg Kim, Jong Pil Im, Hyun Chae Jung, Joo Sung Kim 
World J Gastroenterol 20(45):17084-17091. Published online Dec 7, 2014. doi: 10.3748/wjg.v20.i45.17084
Inhibitory effects of dobutamine on human gastric adenocarcinoma 
Hui-Xia Zheng, Li-Na Wu, Hong Xiao, Qian Du, Jian-Fang Liang 
World J Gastroenterol 20(45):17092-17099. Published online Dec 7, 2014. doi: 10.3748/wjg.v20.i45.17092
Resistant mutants induced by adefovir dipivoxil in hepatitis B virus isolates 
Su-Wen Jiang, Li-Peng Yao, Ai-Rong Hu, Yao-Ren Hu, Shi-Xiang Chen, Tao Xiong, Guo-Sheng Gao, Xiao-Yue Liang, Shi-Xiong Ding, Peng-Jian Weng 
World J Gastroenterol 20(45):17100-17106. Published online Dec 7, 2014. doi: 10.3748/wjg.v20.i45.17100
Case Control Study
Increased circulating zonulin in children with biopsy-proven nonalcoholic fatty liver disease 
Lucia Pacifico, Enea Bonci, Lidia Marandola, Sara Romaggioli, Stefano Bascetta, Claudio Chiesa 
World J Gastroenterol 20(45):17107-17114. Published online Dec 7, 2014. doi: 10.3748/wjg.v20.i45.17107
Retrospective Study
Revision of failed transoral incisionless fundoplication by subsequent laparoscopic Nissen fundoplication 
Awais Ashfaq, Hyun K Rhee, Kristi L Harold 
World J Gastroenterol 20(45):17115-17119. Published online Dec 7, 2014. doi: 10.3748/wjg.v20.i45.17115
Similar clinical characteristics of familial and sporadic inflammatory bowel disease in South Korea 
Sook Hee Chung, Soo Jung Park, Hye Sun Lee, Sung Pil Hong, Jae Hee Cheon, Tae Il Kim, Won Ho Kim 
World J Gastroenterol 20(45):17120-17126. Published online Dec 7, 2014. doi: 10.3748/wjg.v20.i45.17120
Proton pump inhibitor administration delays rebleeding after endoscopic gastric variceal obturation 
Won Seok Jang, Hyun Phil Shin, Joung Il Lee, Kwang Ro Joo, Jae Myung Cha, Jung Won Jeon, Jun Uk Lim 
World J Gastroenterol 20(45):17127-17131. Published online Dec 7, 2014. doi: 10.3748/wjg.v20.i45.17127
Evaluation of prognostic factors on recurrence after curative resections for hepatocellular carcinoma 
Jae Hyun Han, Dong Goo Kim, Gun Hyung Na, Eun Young Kim, Soo Ho Lee, Tae Ho Hong, Young Kyoung You 
World J Gastroenterol 20(45):17132-17140. Published online Dec 7, 2014. doi: 10.3748/wjg.v20.i45.17132
Appropriate treatment strategies improve survival of hepatocellular carcinoma patients with portal vein tumor thrombus 
Jia-Zhou Ye, Yong-Quan Zhang, Hai-Hong Ye, Tao Bai, Liang Ma, Bang-De Xiang, Le-Qun Li 
World J Gastroenterol 20(45):17141-17147. Published online Dec 7, 2014. doi: 10.3748/wjg.v20.i45.17141
Clinical Trials Study
Endoscopic papillary large balloon dilation for removal of bile duct stones 
Yuji Sakai, Toshio Tsuyuguchi, Yoshiaki Kawaguchi, Nobuto Hirata, So Nakaji, Katsuya Kitamura, Shigeru Mikami, Tatsuya Fujimoto, Masashi Ijima, Eishin Kurihara, Shuhei Oana, Takayoshi Nishino, Ryo Tamura, Dai Sakamoto, Masato Nakamura, Takao Nishikawa, Harutoshi Sugiyama, Hitoshi Yoshida, Tetsuya Mine, Osamu Yokosuka 
World J Gastroenterol 20(45):17148-17154. Published online Dec 7, 2014. doi: 10.3748/wjg.v20.i45.17148
Observational Study
Granulo-monocyto apheresis is more effective in mild ulcerative colitis than in moderate to severe disease 
Chiara De Cassan, Edoardo Savarino, Piero Marson, Tiziana Tison, Giorgia Hatem, Giacomo Carlo Sturniolo, Renata D’Incà 
World J Gastroenterol 20(45):17155-17162. Published online Dec 7, 2014. doi: 10.3748/wjg.v20.i45.17155
Circulating tumor cells in pancreatic cancer patients: Enrichment and cultivation 
Vladimir Bobek, Robert Gurlich, Petra Eliasova, Katarina Kolostova 
World J Gastroenterol 20(45):17163-17170. Published online Dec 7, 2014. doi: 10.3748/wjg.v20.i45.17163
Endoscopic findings of gastrointestinal involvement in Chinese patients with Behcet’s disease 
Jun Zou, Yan Shen, Da-Nian Ji, Song-Bai Zheng, Jian-Long Guan 
World J Gastroenterol 20(45):17171-17178. Published online Dec 7, 2014. doi: 10.3748/wjg.v20.i45.17171
Management of isolated superior mesenteric artery dissection 
Peng-Hua Lv, Xi-Cheng Zhang, Li-Fu Wang, Zhao-Lei Chen, Hai-Bin Shi 
World J Gastroenterol 20(45):17179-17184. Published online Dec 7, 2014. doi: 10.3748/wjg.v20.i45.17179
Prospective Study
PolysorbR (an absorbable lactomer) staples, a safe closure technique for distal pancreatic resection 
Gyula Farkas, László Leindler, János Márton, György Lázár, Gyula Farkas Jr 
World J Gastroenterol 20(45):17185-17189. Published online Dec 7, 2014. doi: 10.3748/wjg.v20.i45.17185
Randomized Controlled Trial
Test-based exclusion diets in gastro-esophageal reflux disease patients: A randomized controlled pilot trial 
Michele Caselli, Giovanni Zuliani, Francesca Cassol, Nadia Fusetti, Elena Zeni, Natalina Lo Cascio, Cecilia Soavi, Sergio Gullini 
World J Gastroenterol 20(45):17190-17195. Published online Dec 7, 2014. doi: 10.3748/wjg.v20.i45.17190
Systematic Reviews
Relationship between the exocrine and endocrine pancreas after acute pancreatitis 
Stephanie L M Das, James I C Kennedy, Rinki Murphy, Anthony R J Phillips, John A Windsor, Maxim S Petrov 
World J Gastroenterol 20(45):17196-17205. Published online Dec 7, 2014. doi: 10.3748/wjg.v20.i45.17196
Meta-Analysis
Conventional transarterial chemoembolization vs microsphere embolization in hepatocellular carcinoma: A meta-analysis 
Jia-Yan Ni, Lin-Feng Xu, Wei-Dong Wang, Hong-Liang Sun, Yao-Ting Chen 
World J Gastroenterol 20(45):17206-17217. Published online Dec 7, 2014. doi: 10.3748/wjg.v20.i45.17206
Is hand sewing comparable with stapling for anastomotic leakage after esophagectomy? A meta-analysis 
Quan-Xing Liu, Jia-Xin Min, Xu-Feng Deng, Ji-Gang Dai 
World J Gastroenterol 20(45):17218-17226. Published online Dec 7, 2014. doi: 10.3748/wjg.v20.i45.17218
3D conformal radiotherapy combined with transcatheter arterial chemoembolization for hepatocellular carcinoma 
Li-Qun Zou, Bing-Lan Zhang, Qing Chang, Fu-Ping Zhu, Yan-Yan Li, Yu-Quan Wei, Yong-Song Guan 
World J Gastroenterol 20(45):17227-17234. Published online Dec 7, 2014. doi: 10.3748/wjg.v20.i45.17227
Anterior vs conventional approach hepatectomy for large liver cancer: A meta-analysis 
Lei Li, Hai-Qing Wang, Qing Wang, Jian Yang, Jia-Yin Yang 
World J Gastroenterol 20(45):17235-17243. Published online Dec 7, 2014. doi: 10.3748/wjg.v20.i45.17235
Case Report
Rectal ulcer: Due to ketoprofen, argon plasma coagulation and prostatic brachytherapy 
Thibaud Koessler, Vincent Servois, Pascale Mariani, Emilie Aubert, Wulfran Cacheux 
World J Gastroenterol 20(45):17244-17246. Published online Dec 7, 2014. doi: 10.3748/wjg.v20.i45.17244
Clinical and radiological feature of lymphoepithelial cyst of the pancreas 
Hirofumi Terakawa, Isamu Makino, Hisatoshi Nakagawara, Tomoharu Miyashita, Hidehiro Tajima, Hirohisa Kitagawa, Takashi Fujimura, Dai Inoue, Kazuto Kozaka, Toshifumi Gabata, Tetsuo Ohta 
World J Gastroenterol 20(45):17247-17253. Published online Dec 7, 2014. doi: 10.3748/wjg.v20.i45.17247
Blue rubber bleb nevus syndrome: A case report and literature review 
Xue-Li Jin, Zhao-Hong Wang, Xi-Bin Xiao, Lian-Sheng Huang, Xiao-Ying Zhao 
World J Gastroenterol 20(45):17254-17259. Published online Dec 7, 2014. doi: 10.3748/wjg.v20.i45.17254
Resection of a cholangiocarcinoma via laparoscopic hepatopancreato- duodenectomy: A case report 
Miao-Zun Zhang, Xiao-Wu Xu, Yi-Ping Mou, Jia-Fei Yan, Yi-Ping Zhu, Ren-Chao Zhang, Yu-Cheng Zhou, Ke Chen, Wei-Wei Jin, Erik Matro, Harsha Ajoodhea 
World J Gastroenterol 20(45):17260-17264. Published online Dec 7, 2014. doi: 10.3748/wjg.v20.i45.17260