Published online Dec 7, 2014. doi: 10.3748/wjg.v20.i45.17206
Revised: April 19, 2014
Accepted: July 22, 2014
Published online: December 7, 2014
Core tip: Microsphere embolization has been performed more and more widely for the treatment of hepatocellular carcinoma (HCC). Whether microsphere embolization or conventional transarterial chemoembolization (c-TACE) is the better choice has been debated. In this study, we performed a meta-analysis to comprehensively compare the efficacy and safety of microspheres embolization with those of c-TACE in HCC. Our analysis indicated that microsphere embolization was associated with superior survival and treatment response in comparison with c-TACE in patients with HCC. We hope that the comparison of these treatments could help stratify the benefits of treatment choices for patients with HCC.