Granulo-monocyto apheresis is more effective in mild ulcerative colitis than in moderate to severe disease

Table 1 Clinical and demographic characteristics of the enrolled population

	Total population (n = 41)	Mild (n = 28)	Moderate to severe (n =13)	P value
Sex: M	24	14	10	0.17
Age: mean (range)	47 (16-82)	48 (19-73)	44 (16-82)	0.44
Disease duration before apheresis: median (range)	8 (1-31)	10 (1-31)	4 (1-11)	0.02
Disease localisation:		1	0
Proctitis	1	9	1
Left	10	18	12
Extensive	30
Steroid experience:
Steroid resistance	6	2	4	0.06
Steroid dependence	33	26	7	0.007
Steroid intolerance	2	0	2	0.09
Previous treatments:			6	1
Immunosuppressants	20	14	2	0.64
Biologics	5	3
Concomitant treatments:
Steroids	15	10	5	1
Immunosuppressants	8	5	3	0.69
Biologics	0	0	0	1
Reasons for apheresis:
Immunosuppressants resistance/intolerance/contraindications	15	12	3	0.3
Biologics resistance/intolerance/contraindications	1	1	0	1
Biologics and immune suppressors resistance/intolerance/contraindications	6	3	3	0.3
Others	19	12	7	0.7
Mean CRP (range) at study entry (normal if < 5 mg/dL)	13.6 (1-73)	11.6 (0.1-73)	15.2 (1.22-61)	0.67
Mean Lactoferrin (range) at study entry (normal if < 7 μg/g faeces)	84.55 (13-100)	80.71 (13-100)	85.9 (28-100)	0.7