Retrospective Study
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World J Gastroenterol. Dec 7, 2014; 20(45): 17120-17126
Published online Dec 7, 2014. doi: 10.3748/wjg.v20.i45.17120
Similar clinical characteristics of familial and sporadic inflammatory bowel disease in South Korea
Sook Hee Chung, Soo Jung Park, Hye Sun Lee, Sung Pil Hong, Jae Hee Cheon, Tae Il Kim, Won Ho Kim
Sook Hee Chung, Soo Jung Park, Sung Pil Hong, Jae Hee Cheon, Tae Il Kim, Won Ho Kim, Department of Internal Medicine and Institute of Gastroenterology, Yonsei University College of Medicine, Seoul 120-752, South Korea
Sook Hee Chung, Department of Internal Medicine and institute of Gastroenterology, Ajou University College of Medicine, Suwon 443-380, South Korea
Hye Sun Lee, Department of Biostatistics, Yonsei University College of Medicine, Seoul 120-752, South Korea
Author contributions: Chung SH wrote the article; Park SJ designed the study and analyzed the data; Lee HS provided consultation about statistics; Hong SP, Cheon JH, Kim TI and Kim WH reviewed the manuscript.
Correspondence to: Soo Jung Park, MD, PhD, Clinical Assistant Professor, Department of Internal Medicine and Institute of Gastroenterology, Yonsei University College of Medicine, 50-1 Yonseiro, Seodaemun-gu, Seoul 120-752, South Korea. sjpark@yuhs.ac
Telephone: +82-2-22281963 Fax: +82-2-3652125
Received: February 26, 2014
Revised: April 29, 2014
Accepted: July 24, 2014
Published online: December 7, 2014
Core Tip

Core tip: We investigated differences of clinical characteristics and disease courses between familial and sporadic inflammatory bowel disease (IBD) patients. Despite several other studies of IBD, there is still insufficient knowledge regarding the clinical characteristics in familial IBD. We report that a family history of IBD does not seem to be an important predictive factor affecting clinical characteristics or disease course. Not only genetic background but also environmental factors might affect the disease course of IBD.