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World J Gastroenterol. Dec 7, 2014; 20(45): 17155-17162
Published online Dec 7, 2014. doi: 10.3748/wjg.v20.i45.17155
Published online Dec 7, 2014. doi: 10.3748/wjg.v20.i45.17155
Granulo-monocyto apheresis is more effective in mild ulcerative colitis than in moderate to severe disease
Chiara De Cassan, Edoardo Savarino, Giorgia Hatem, Giacomo Carlo Sturniolo, Renata D’Incà, Division of Gastroenterology, Department of Surgery, Oncology and Gastroenterology, University of Padua, 35128 Padua, Italy
Piero Marson, Tiziana Tison, Apheresis Unit, Blood Transfusion Service, University of Padua, 35128 Padua, Italy
Author contributions: De Cassan C, Savarino E, Marson P, Tison T, Hatem G, Sturniolo GC and D’Incà R design of the study, analysis and interpretation of the data, drafting of the article, critical revision of the article for important intellectual content, final approval of the article.
Correspondence to: Chiara De Cassan, MD, Division of Gastroenterology, Department of Surgery, Oncology and Gastroenterology, University of Padua, via Giustiniani 2, 35128 Padua, Italy. chiaradecassan@gmail.com
Telephone: +39-49-8217749 Fax: +39-49-8760820
Received: January 27, 2014
Revised: May 17, 2014
Accepted: June 26, 2014
Published online: December 7, 2014
Revised: May 17, 2014
Accepted: June 26, 2014
Published online: December 7, 2014
Core Tip
Core tip: Several studies evaluating granulo-monocyto apheresis in ulcerative colitis have been previously conducted, and these studies have shown conflicting results. We performed a retrospective study evaluating granulo-monocyto apheresis effectiveness according to disease severity. Granulo-monocyto-mpheresis was found to be more effective in patients with mild disease activity than in patients with moderate to severe disease activity.