Chemopreventive effect of apple and berry fruits against colon cancer

doi:10.3748/wjg.v20.i45.17029

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Dec 7, 2014 (publication date) through Apr 26, 2024

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World Journal of Gastroenterology

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1007-9327

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World J Gastroenterol. Dec 7, 2014; 20(45): 17029-17036
Published online Dec 7, 2014. doi: 10.3748/wjg.v20.i45.17029

Chemopreventive effect of apple and berry fruits against colon cancer

Saravana Kumar Jaganathan, Muthu Vignesh Vellayappan, Gayathri Narasimhan, Eko Supriyanto, Dyah Ekashanti Octorina Dewi, Aqilah Leela T Narayanan, Arunpandian Balaji, Aruna Priyadarshini Subramanian, Mustafa Yusof

Saravana Kumar Jaganathan, Eko Supriyanto, Dyah Ekashanti Octorina Dewi, Aqilah Leela T Narayanan, Mustafa Yusof, IJN-UTM Cardiovascular Engineering Centre, Faculty of Bioscience and Medical Engineering, Universiti Teknologi Malaysia, Johor Bahru 81310, Malaysia

Muthu Vignesh Vellayappan, Arunpandian Balaji, Aruna Priyadarshini Subramanian, Department of Research and Development, PSNA College of Engineering and Technology, Kothandaraman Nagar, Tamil Nadu, Dindigul 624622, India

Gayathri Narasimhan, Department of Pharmacology, Cinvestav-IPN, Mexico city 07360, Mexico

Author contributions: Jaganathan SK designed the research; Jaganathan SK, Vellayappan MV, Narasimhan G, Balaji A and Subramanian AP collected the literature; Vellayappan MV and Narasimhan G wrote the review in consultation with Jaganathan SK; Narasimhan G, Supriyanto E, Octorina Dewi DE, Narayanan ALT, Arunpandian B and Subramanian AP participated in editing of manuscript by providing suggestions; Yusof M had checked the overall integrity of manuscript during revision by providing suggestions; all the authors verified the final manuscript.

Supported by (in part) Ministry of Higher Education Malaysia with the Grant Vot, No. R.J130000.7809.4F444 and the Ref No. PY/2014/03167; Part of the grant with the Vot, No. 04H93, Ministry of Education was also used for this study

Correspondence to: Saravana Kumar Jaganathan, Senior Lecturer, IJN-UTM Cardiovascular Engineering Centre, Faculty of Bioscience and Medical Engineering, Universiti Teknologi Malaysia, Skudai, Johor Bahru 81310, Malaysia. jaganathaniitkgp@gmail.com

Telephone: +60-7-5558563 Fax: +60-7-5558553

Received: April 11, 2014
Revised: June 16, 2014
Accepted: August 13, 2014
Published online: December 7, 2014

Core Tip

Core tip: Colon cancer is one of the leading causes of death worldwide. Chemoprevention of colon cancer using various dietary agents is an area of current interest. This manuscript reviews the chemopreventive potential of apple and berry juices against colon cancer. This work will further promote the importance of dietary fruit juices in colon cancer prevention.