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Topic Highlight
Hepatitis C-associated liver carcinogenesis: Role of PML nuclear bodies 
Kerstin Herzer, Guido Gerken, Thomas G Hofmann 
World J Gastroenterol 20(35):12367-12371. Published online Sep 21, 2014. doi: 10.3748/wjg.v20.i35.12367
Extrahepatic immune related manifestations in chronic hepatitis C virus infection 
Maria Tampaki, John Koskinas 
World J Gastroenterol 20(35):12372-12380. Published online Sep 21, 2014. doi: 10.3748/wjg.v20.i35.12372
Smad3 phospho-isoform signaling in hepatitis C virus-related chronic liver diseases 
Takashi Yamaguchi, Katsunori Yoshida, Miki Murata, Koichi Matsuzaki 
World J Gastroenterol 20(35):12381-12390. Published online Sep 21, 2014. doi: 10.3748/wjg.v20.i35.12381
Colorectal cancer with liver metastases: Neoadjuvant chemotherapy, surgical resection first or palliation alone? 
Khurum Khan, Anita Wale, Gina Brown, Ian Chau 
World J Gastroenterol 20(35):12391-12406. Published online Sep 21, 2014. doi: 10.3748/wjg.v20.i35.12391
Immune reaction and colorectal cancer: Friends or foes? 
Vincenzo Formica, Vittore Cereda, Antonella Nardecchia, Manfredi Tesauro, Mario Roselli 
World J Gastroenterol 20(35):12407-12419. Published online Sep 21, 2014. doi: 10.3748/wjg.v20.i35.12407
Early-onset colorectal cancer: A sporadic or inherited disease? 
Vittoria Stigliano, Lupe Sanchez-Mete, Aline Martayan, Marcello Anti 
World J Gastroenterol 20(35):12420-12430. Published online Sep 21, 2014. doi: 10.3748/wjg.v20.i35.12420
Occupational exposures and colorectal cancers: A quantitative overview of epidemiological evidence 
Enrico Oddone, Carlo Modonesi, Gemma Gatta 
World J Gastroenterol 20(35):12431-12444. Published online Sep 21, 2014. doi: 10.3748/wjg.v20.i35.12431
Improving the outcomes in oncological colorectal surgery 
Jeroen LA van Vugt, Kostan W Reisinger, Joep PM Derikx, Djamila Boerma, Jan HMB Stoot 
World J Gastroenterol 20(35):12445-12457. Published online Sep 21, 2014. doi: 10.3748/wjg.v20.i35.12445
Clinical impact of minimal cancer cell detection in various colorectal cancer specimens 
Kazuhiko Yoshimatsu, Hajime Yokomizo, Yoshihiko Naritaka 
World J Gastroenterol 20(35):12458-12461. Published online Sep 21, 2014. doi: 10.3748/wjg.v20.i35.12458
Potential mechanisms of hepatitis B virus induced liver injury 
Mohd Suhail, Hany Abdel-Hafiz, Ashraf Ali, Kaneez Fatima, Ghazi A Damanhouri, Esam Azhar, Adeel GA Chaudhary, Ishtiaq Qadri 
World J Gastroenterol 20(35):12462-12472. Published online Sep 21, 2014. doi: 10.3748/wjg.v20.i35.12462
Resection of hepatitis B virus-related hepatocellular carcinoma: Evolving strategies and emerging therapies to improve outcome 
Gar-Yang Chau 
World J Gastroenterol 20(35):12473-12484. Published online Sep 21, 2014. doi: 10.3748/wjg.v20.i35.12473
Review
Current treatment options for colon cancer peritoneal carcinomatosis 
Tomoyoshi Aoyagi, Krista P Terracina, Ali Raza, Kazuaki Takabe 
World J Gastroenterol 20(35):12493-12500. Published online Sep 21, 2014. doi: 10.3748/wjg.v20.i35.12493
Treatment for superficial non-ampullary duodenal epithelial tumors 
Naomi Kakushima, Hideyuki Kanemoto, Masaki Tanaka, Kohei Takizawa, Hiroyuki Ono 
World J Gastroenterol 20(35):12501-12508. Published online Sep 21, 2014. doi: 10.3748/wjg.v20.i35.12501
Minireviews
Routine colonic endoscopic evaluation following resolution of acute diverticulitis: Is it necessary? 
Amit K Agarwal, Burzeen E Karanjawala, Justin A Maykel, Eric K Johnson, Scott R Steele 
World J Gastroenterol 20(35):12509-12516. Published online Sep 21, 2014. doi: 10.3748/wjg.v20.i35.12509
Eltrombopag in chronic hepatitis C 
Romeo-Gabriel Mihăilă, Remus-Călin Cipăian 
World J Gastroenterol 20(35):12517-12521. Published online Sep 21, 2014. doi: 10.3748/wjg.v20.i35.12517
Mitotic crossover - an evolutionary rudiment which promotes carcinogenesis of colorectal carcinoma 
Branislav Rovcanin, Ivan Ivanovski, Olivera Djuric, Dimitrije Nikolic, Jelena Petrovic, Petar Ivanovski 
World J Gastroenterol 20(35):12522-12525. Published online Sep 21, 2014. doi: 10.3748/wjg.v20.i35.12522
Necroptosis: An emerging type of cell death in liver diseases 
Waqar Khalid Saeed, Dae Won Jun 
World J Gastroenterol 20(35):12526-12532. Published online Sep 21, 2014. doi: 10.3748/wjg.v20.i35.12526
Original Article
Protective action of NADPH oxidase inhibitors and role of NADPH oxidase in pathogenesis of colon inflammation in mice 
Rima Ramonaite, Jurgita Skieceviciene, Simonas Juzenas, Violeta Salteniene, Juozas Kupcinskas, Paulius Matusevicius, Vilmante Borutaite, Limas Kupcinskas 
World J Gastroenterol 20(35):12533-12541. Published online Sep 21, 2014. doi: 10.3748/wjg.v20.i35.12533
Role of ERK-MAPK signaling pathway in pentagastrin-regulated growth of large intestinal carcinoma 
Jia-Ding Mao, Pei Wu, Jian-Xiong Huang, Jian Wu, Guang Yang 
World J Gastroenterol 20(35):12542-12550. Published online Sep 21, 2014. doi: 10.3748/wjg.v20.i35.12542
Research Report
Extraesophageal saline enhances endoscopic ultrasonography to differentiate esophagus and adjacent organs 
Jian-Jun Li, Hong-Bo Shan, Long-Jun He, Thomas D Wang, Huan Xiong, Li-Ming Chen, Xiao-Hai Li, Xin-Xin Huang, Guang-Yu Luo, Yin Li, Guo-Liang Xu 
World J Gastroenterol 20(35):12551-12558. Published online Sep 21, 2014. doi: 10.3748/wjg.v20.i35.12551
Evidence-Based Medicine
Polymorphism of heat shock protein 70-2 and enterocutaneous fistula in Chinese population 
Jun Chen, Jian-An Ren, Gang Han, Guo-Sheng Gu, Ge-Fei Wang, Xiu-Wen Wu, Bo Zhou, Dong Hu, Yin Wu, Yun-Zhao Zhao, Jie-Shou Li 
World J Gastroenterol 20(35):12559-12565. Published online Sep 21, 2014. doi: 10.3748/wjg.v20.i35.12559
Case Control Study
Serum immunoglobulin A concentration is a reliable biomarker for liver fibrosis in non-alcoholic fatty liver disease 
Iradj Maleki, Mahmood Reza Aminafshari, Tarang Taghvaei, Vahid Hosseini, Alireza Rafiei, Zhila Torabizadeh, Maryam Barzin, Elahe Orang 
World J Gastroenterol 20(35):12566-12573. Published online Sep 21, 2014. doi: 10.3748/wjg.v20.i35.12566
Retrospective Study
Parameters of a severe disease course in ulcerative colitis 
Andreas Stallmach, Luisa Nickel, Thomas Lehmann, Bernd Bokemeyer, Martin Bürger, Dietrich Hüppe, Wolfgang Kruis, Susanna Nikolaus, Jan C Preiss, Andreas Sturm, Niels Teich, Carsten Schmidt 
World J Gastroenterol 20(35):12574-12580. Published online Sep 21, 2014. doi: 10.3748/wjg.v20.i35.12574
Indicators of sorafenib efficacy in patients with advanced hepatocellular carcinoma 
Masayoshi Yada, Akihide Masumoto, Kenta Motomura, Hirotaka Tajiri, Yusuke Morita, Hideo Suzuki, Takeshi Senju, Toshimasa Koyanagi 
World J Gastroenterol 20(35):12581-12587. Published online Sep 21, 2014. doi: 10.3748/wjg.v20.i35.12581
Short-term interval combined chemoembolization and radiofrequency ablation for hepatocellular carcinoma 
Won Hyeok Choe, Young Jun Kim, Hee Sun Park, Sang Woo Park, Jeong Han Kim, So Young Kwon 
World J Gastroenterol 20(35):12588-12594. Published online Sep 21, 2014. doi: 10.3748/wjg.v20.i35.12588
Preoperative differential diagnosis between intrahepatic biliary cystadenoma and cystadenocarcinoma: A single-center experience 
Fu-Bo Zhang, Ai-Min Zhang, Zhi-Bin Zhang, Xin Huang, Xi-Tao Wang, Jia-Hong Dong 
World J Gastroenterol 20(35):12595-12601. Published online Sep 21, 2014. doi: 10.3748/wjg.v20.i35.12595
Botulinum toxin type-A injection to treat patients with intractable anismus unresponsive to simple biofeedback training 
Yong Zhang, Zhen-Ning Wang, Lei He, Ge Gao, Qing Zhai, Zhi-Tao Yin, Xian-Dong Zeng 
World J Gastroenterol 20(35):12602-12607. Published online Sep 21, 2014. doi: 10.3748/wjg.v20.i35.12602
Observational Study
Cardiac surgery in patients with liver cirrhosis: Risk factors for predicting mortality 
Cheng-Hsin Lin, Ron-Bin Hsu 
World J Gastroenterol 20(35):12608-12614. Published online Sep 21, 2014. doi: 10.3748/wjg.v20.i35.12608
Risk factors for combined hepatocellular-cholangiocarcinoma: A hospital-based case-control study 
Yan-Ming Zhou, Xiao-Feng Zhang, Lu-Peng Wu, Cheng-Jun Sui, Jia-Mei Yang 
World J Gastroenterol 20(35):12615-12620. Published online Sep 21, 2014. doi: 10.3748/wjg.v20.i35.12615
Prospective Study
Optimal b value of diffusion-weighted imaging on a 3.0T magnetic resonance scanner in Crohn’s disease 
Qi Feng, Yun-Qi Yan, Jiong Zhu, Jin-Lu Tong, Jian-Rong Xu 
World J Gastroenterol 20(35):12621-12627. Published online Sep 21, 2014. doi: 10.3748/wjg.v20.i35.12621
Contrast-enhanced ultrasound: Improving the preoperative staging of hepatocellular carcinoma and guiding individual treatment 
Xiao-Yun Zhang, Yan Luo, Tian-Fu Wen, Li Jiang, Chuan Li, Xiao-Fei Zhong, Jing-Yi Zhang, Wen-Wu Ling, Lu-Nan Yan, Yong Zeng, Hong Wu 
World J Gastroenterol 20(35):12628-12636. Published online Sep 21, 2014. doi: 10.3748/wjg.v20.i35.12628
Meta-Analysis
Pharmacological interventions for improved colonic anastomotic healing: A meta-analysis 
Mari Nanna Øines, Peter-Martin Krarup, Lars Nannestad Jorgensen, Magnus Sven Ågren 
World J Gastroenterol 20(35):12637-12648. Published online Sep 21, 2014. doi: 10.3748/wjg.v20.i35.12637
Kudo’s pit pattern classification for colorectal neoplasms: A meta-analysis 
Ming Li, Syed Mohsin Ali, Syeda Umm-a-OmarahGilani, Jing Liu, Yan-Qing Li, Xiu-Li Zuo 
World J Gastroenterol 20(35):12649-12656. Published online Sep 21, 2014. doi: 10.3748/wjg.v20.i35.12649
Case Report
Hepatoid adenocarcinoma of the colon in a patient with inflammatory bowel disease 
Yuanyuan Chen, David F Schaeffer, Eric M Yoshida 
World J Gastroenterol 20(35):12657-12661. Published online Sep 21, 2014. doi: 10.3748/wjg.v20.i35.12657
Association of autoimmune hepatitis and systemic lupus erythematodes: A case series and review of the literature 
Claudia Beisel, Christina Weiler-Normann, Andreas Teufel, Ansgar W Lohse 
World J Gastroenterol 20(35):12662-12667. Published online Sep 21, 2014. doi: 10.3748/wjg.v20.i35.12662
Ruptured gastric artery aneurysm: An uncommon manifestation of microscopic polyangiitis 
Yoshihiro Ikura, Tomohiro Kadota, Shuhei Watanabe, Akira Arimoto, Eiko Nishioka 
World J Gastroenterol 20(35):12668-12672. Published online Sep 21, 2014. doi: 10.3748/wjg.v20.i35.12668
Esophageal early basaloid squamous carcinoma with unusual narrowband imaging magnified endoscopy findings 
Yugo Kai, Motohiko Kato, Yoshito Hayashi, Tomofumi Akasaka, Shinichiro Shinzaki, Tsutomu Nishida, Masahiko Tsujii, Eiichi Morii, Tetsuo Takehara 
World J Gastroenterol 20(35):12673-12677. Published online Sep 21, 2014. doi: 10.3748/wjg.v20.i35.12673
Intussusception due to rectal adenocarcinoma in a young adult: A case report 
Ryo Inada, Takeshi Nagasaka, Toshiaki Toshima, Yoshiko Mori, Yoshitaka Kondo, Hiroyuki Kishimoto, Toshiyoshi Fujiwara 
World J Gastroenterol 20(35):12678-12681. Published online Sep 21, 2014. doi: 10.3748/wjg.v20.i35.12678
Pancreatic adenocarcinosarcoma of monoclonal origin: A case report 
Hyun Seon Kim, Jin Il Kim, Minyoung Jeong, Jae Hyun Seo, Il Kyu Kim, Dae Young Cheung, Tae-Jung Kim, Chang Suk Kang 
World J Gastroenterol 20(35):12682-12686. Published online Sep 21, 2014. doi: 10.3748/wjg.v20.i35.12682
A case of Clostridium difficile infection complicated by acute respiratory distress syndrome treated with fecal microbiota transplantation 
Ji Eun Kim, Tae-Geun Gweon, Chang Dong Yeo, Young-Seok Cho, Gi Jun Kim, Jae Young Kim, Jong Wook Kim, Hyunho Kim, Hye Won Lee, Taeseok Lim, Hyoju Ham, Hyun Jin Oh, Yeongbok Lee, Jaeho Byeon, Sung Soo Park 
World J Gastroenterol 20(35):12687-12690. Published online Sep 21, 2014. doi: 10.3748/wjg.v20.i35.12687
Esophageal squamous cell carcinoma with dural and bone marrow metastases 
Yen-Hao Chen, Cheng-Hua Huang 
World J Gastroenterol 20(35):12691-12695. Published online Sep 21, 2014. doi: 10.3748/wjg.v20.i35.12691
Successful surgical strategy in a late case of Boerhaave’s syndrome 
Gang Shen, Ying Chai, Guo-Fei Zhang 
World J Gastroenterol 20(35):12696-12700. Published online Sep 21, 2014. doi: 10.3748/wjg.v20.i35.12696
Successful esophagectomy in a patient with combined esophageal cancer and hemophilia B 
Guo-Fei Zhang, Ying Chai, Wen-Shan Li, Lian-Sheng Huang, Gang Shen 
World J Gastroenterol 20(35):12701-12703. Published online Sep 21, 2014. doi: 10.3748/wjg.v20.i35.12701
Rare cause of upper gastrointestinal bleeding owing to hepatic cancer invasion: A case report 
Wei-Ding Wu, Jia Wu, Hong-Guo Yang, Yuan Chen, Cheng-Wu Zhang, Da-Jian Zhao, Zhi-Ming Hu 
World J Gastroenterol 20(35):12704-12708. Published online Sep 21, 2014. doi: 10.3748/wjg.v20.i35.12704
Letters To The Editor
May bacterial or pancreatic proteases play a critical role in inflammatory bowel disease? 
Xiaofa Qin 
World J Gastroenterol 20(35):12709-12710. Published online Sep 21, 2014. doi: 10.3748/wjg.v20.i35.12709
Is increased red cell distribution width an indicating marker of nonalcoholic steatohepatitis and fibrotic stage? 
Huseyin Kayadibi, Erdim Sertoglu, Metin Uyanik, Serkan Tapan 
World J Gastroenterol 20(35):12711-12712. Published online Sep 21, 2014. doi: 10.3748/wjg.v20.i35.12711