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World J Gastroenterol. Sep 21, 2014; 20(35): 12509-12516
Published online Sep 21, 2014. doi: 10.3748/wjg.v20.i35.12509
Routine colonic endoscopic evaluation following resolution of acute diverticulitis: Is it necessary?
Amit K Agarwal, Burzeen E Karanjawala, Justin A Maykel, Eric K Johnson, Scott R Steele
Amit K Agarwal, Department of Surgery, University of Texas Health Science Center-Houston, Houston, TX 77030, United States
Burzeen E Karanjawala, Department of Surgery, University of Texas Health Science Center-Houston and Lyndon B. Johnson General Hospital, Houston, TX 77026, United States
Justin A Maykel, University of Massachusetts Memorial Medical Center, Worcester, MA 01605, United States
Eric K Johnson, Scott R Steele, Colon Rectal Surgery, Department of Surgery, Madigan Army Medical Center, Tacoma, WA 98431, United States
Author contributions: Agarwal AK and Karanjawala BE contributed equally to this work; Agarwal AK, Karanjawala BE and Steele SR designed research; Agarwal AK, Karanjawala BE and Steele SR performed research; Makel JA and Johnson EK contributed expertise knowledge and performed critical revision on the paper; Agarwal AK, Karanjawala BE and Steele SR authored the paper and helped with critical revision.
Correspondence to: Scott R Steele, MD, Chief of Colon Rectal Surgery, Department of Surgery, Madigan Army Medical Center, Tacoma, WA 98431, United States. harkersteele@mac.com
Telephone: +1-253-9682200 Fax:+1-253-9685900
Received: February 20, 2014
Revised: April 10, 2014
Accepted: May 25, 2014
Published online: September 21, 2014
Abstract

Diverticular disease incidence is increasing up to 65% by age 85 in industrialized nations, low fiber diets, and in younger and obese patients. Twenty-five percent of patients with diverticulosis will develop acute diverticulitis. This imposes a significant burden on healthcare systems, resulting in greater than 300000 admissions per year with an estimated annual cost of $3 billion USD. Abdominal computed tomography (CT) is the diagnostic study of choice, with a sensitivity and specificity greater than 95%. Unfortunately, similar CT findings can be present in colonic neoplasia, especially when perforated or inflamed. This prompted professional societies such as the American Society of Colon Rectal Surgeons to recommend patients undergo routine colonoscopy after an episode of acute diverticulitis to rule out malignancy. Yet, the data supporting routine colonoscopy after acute diverticulitis is sparse and based small cohort studies utilizing outdated technology. While any patient with an indication for a colonoscopy should undergo appropriate endoscopic evaluation, in the era of widespread use of high-resolution computed tomography, routine colonic endoscopic evaluation following resolution of acute uncomplicated diverticulitis poses additional costs, comes with inherent risks, and may require further study. In this manuscript, we review the current data related to this recommendation.

Keywords: Colonic evaluation, Colonoscopy, Diverticulitis, Acute diverticulitis, Colonic neoplasia, Endoscopy

Core tip: Acute diverticulitis accounts for greater than 300000 hospital admissions a year in the United States alone. Current guidelines suggest that routine colonic evaluation is recommended following recovery from an episode of acute diverticulitis to confirm the diagnosis and exclude malignancy. Current data suggests that the presence of colonic neoplasia after an optimal high-resolution computed tomography that demonstrates uncomplicated diverticulitis will be low. Accordingly, routine colonic endoscopic evaluation following treatment of computed tomography-diagnosed acute uncomplicated diverticulitis may deserve further study.