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Editorial
Contribution of TLR signaling to the pathogenesis of colitis-associated cancer in inflammatory bowel disease 
Ferenc Sipos, István Fűri, Miklós Constantinovits, Zsolt Tulassay, Györgyi Műzes 
World J Gastroenterol 20(36):12713-12721. Published online Sep 28, 2014. doi: 10.3748/wjg.v20.i36.12713
Topic Highlight
Eligibility of persons who inject drugs for treatment of hepatitis C virus infection 
Amber Arain, Geert Robaeys 
World J Gastroenterol 20(36):12722-12733. Published online Sep 28, 2014. doi: 10.3748/wjg.v20.i36.12722
Potential for human immunodeficiency virus parenteral transmission in the Middle East and North Africa: An analysis using hepatitis C virus as a proxy biomarker 
Yousra A Mohamoud, F DeWolfe Miller, Laith J Abu-Raddad 
World J Gastroenterol 20(36):12734-12752. Published online Sep 28, 2014. doi: 10.3748/wjg.v20.i36.12734
Immune evasion strategies used by Helicobacter pylori 
Taslima T Lina, Shatha Alzahrani, Jazmin Gonzalez, Irina V Pinchuk, Ellen J Beswick, Victor E Reyes 
World J Gastroenterol 20(36):12753-12766. Published online Sep 28, 2014. doi: 10.3748/wjg.v20.i36.12753
Effect of Helicobacter pylori on gastric epithelial cells 
Shatha Alzahrani, Taslima T Lina, Jazmin Gonzalez, Irina V Pinchuk, Ellen J Beswick, Victor E Reyes 
World J Gastroenterol 20(36):12767-12780. Published online Sep 28, 2014. doi: 10.3748/wjg.v20.i36.12767
Beyond the stomach: An updated view of Helicobacter pylori pathogenesis, diagnosis, and treatment 
Traci L Testerman, James Morris 
World J Gastroenterol 20(36):12781-12808. Published online Sep 28, 2014. doi: 10.3748/wjg.v20.i36.12781
Role of Helicobacter pylori infection on nutrition and metabolism 
Francesco Franceschi, Annalisa Tortora, Teresa Di Rienzo, Giovanna D’Angelo, Gianluca Ianiro, Franco Scaldaferri, Viviana Gerardi, Valentina Tesori, Loris Riccardo Lopetuso, Antonio Gasbarrini 
World J Gastroenterol 20(36):12809-12817. Published online Sep 28, 2014. doi: 10.3748/wjg.v20.i36.12809
Hematologic manifestations of Helicobacter pylori infection 
Germán Campuzano-Maya 
World J Gastroenterol 20(36):12818-12838. Published online Sep 28, 2014. doi: 10.3748/wjg.v20.i36.12818
Role of Helicobacter pylori infection in autoimmune systemic rheumatic diseases 
Mislav Radić 
World J Gastroenterol 20(36):12839-12846. Published online Sep 28, 2014. doi: 10.3748/wjg.v20.i36.12839
Diagnosis of Helicobacter pylori: What should be the gold standard? 
Saurabh Kumar Patel, Chandra Bhan Pratap, Ashok Kumar Jain, Anil Kumar Gulati, Gopal Nath 
World J Gastroenterol 20(36):12847-12859. Published online Sep 28, 2014. doi: 10.3748/wjg.v20.i36.12847
Helicobacter pylori infection, gastrin and cyclooxygenase-2 in gastric carcinogenesis 
Yun Shao, Kun Sun, Wei Xu, Xiao-Lin Li, Hong Shen, Wei-Hao Sun 
World J Gastroenterol 20(36):12860-12873. Published online Sep 28, 2014. doi: 10.3748/wjg.v20.i36.12860
Potential role of metabolomics in diagnosis and surveillance of gastric cancer 
Angela W Chan, Richdeep S Gill, Daniel Schiller, Michael B Sawyer 
World J Gastroenterol 20(36):12874-12882. Published online Sep 28, 2014. doi: 10.3748/wjg.v20.i36.12874
Problems faced by evidence-based medicine in evaluating lymphadenectomy for gastric cancer 
Giuseppe Verlato, Simone Giacopuzzi, Maria Bencivenga, Paolo Morgagni, Giovanni De Manzoni 
World J Gastroenterol 20(36):12883-12891. Published online Sep 28, 2014. doi: 10.3748/wjg.v20.i36.12883
Multimodality treatment of potentially curative gastric cancer: Geographical variations and future prospects 
Neil D Merrett 
World J Gastroenterol 20(36):12892-12899. Published online Sep 28, 2014. doi: 10.3748/wjg.v20.i36.12892
Postoperative adjuvant chemoradiotherapy in D2-dissected gastric cancer: Is radiotherapy necessary after D2-dissection? 
Jee Suk Chang, Woong Sub Koom, Youngin Lee, Hong In Yoon, Hyung Sik Lee 
World J Gastroenterol 20(36):12900-12907. Published online Sep 28, 2014. doi: 10.3748/wjg.v20.i36.12900
New advances in molecular mechanisms and emerging therapeutic targets in alcoholic liver diseases 
Jessica A Williams, Sharon Manley, Wen-Xing Ding 
World J Gastroenterol 20(36):12908-12933. Published online Sep 28, 2014. doi: 10.3748/wjg.v20.i36.12908
Alcoholic liver disease: Treatment 
Ki Tae Suk, Moon Young Kim, Soon Koo Baik 
World J Gastroenterol 20(36):12934-12944. Published online Sep 28, 2014. doi: 10.3748/wjg.v20.i36.12934
Hepatocellular carcinoma in nonalcoholic fatty liver: Role of environmental and genetic factors 
Paola Dongiovanni, Stefano Romeo, Luca Valenti 
World J Gastroenterol 20(36):12945-12955. Published online Sep 28, 2014. doi: 10.3748/wjg.v20.i36.12945
Non-alcoholic fatty liver disease: What the clinician needs to know 
Mariana Verdelho Machado, Helena Cortez-Pinto 
World J Gastroenterol 20(36):12956-12980. Published online Sep 28, 2014. doi: 10.3748/wjg.v20.i36.12956
Laparoscopic natural orifice specimen extraction-colectomy: A systematic review 
Albert M Wolthuis, Anthony de Buck van Overstraeten, André D’Hoore 
World J Gastroenterol 20(36):12981-12992. Published online Sep 28, 2014. doi: 10.3748/wjg.v20.i36.12981
Endoscopic features of gastro-intestinal lymphomas: From diagnosis to follow-up 
Calogero Vetro, Alessandra Romano, Irene Amico, Concetta Conticello, Giovanna Motta, Amalia Figuera, Annalisa Chiarenza, Cosimo Di Raimondo, Giorgio Giulietti, Giacomo Bonanno, Giuseppe Alberto Palumbo, Francesco Di Raimondo 
World J Gastroenterol 20(36):12993-13005. Published online Sep 28, 2014. doi: 10.3748/wjg.v20.i36.12993
Is there a role for colon capsule endoscopy beyond colorectal cancer screening? A literature review 
Konstantinos Triantafyllou, Iosif Beintaris, George D Dimitriadis 
World J Gastroenterol 20(36):13006-13014. Published online Sep 28, 2014. doi: 10.3748/wjg.v20.i36.13006
Endoscopic treatment of esophageal varices in patients with liver cirrhosis 
Christos Triantos, Maria Kalafateli 
World J Gastroenterol 20(36):13015-13026. Published online Sep 28, 2014. doi: 10.3748/wjg.v20.i36.13015
Improving quality measures in colonoscopy and its therapeutic intervention 
Akira Horiuchi, Naoki Tanaka 
World J Gastroenterol 20(36):13027-13034. Published online Sep 28, 2014. doi: 10.3748/wjg.v20.i36.13027
Minimally invasive surgery for submucosal (subepithelial) tumors of the stomach 
Chang Min Lee, Hyung-Ho Kim 
World J Gastroenterol 20(36):13035-13043. Published online Sep 28, 2014. doi: 10.3748/wjg.v20.i36.13035
Capsule endoscopy in Crohn’s disease: Are we seeing any better? 
David Hudesman, Jonathan Mazurek, Arun Swaminath 
World J Gastroenterol 20(36):13044-13051. Published online Sep 28, 2014. doi: 10.3748/wjg.v20.i36.13044
Anal squamous cell carcinoma: An evolution in disease and management 
Marc C Osborne, Justin Maykel, Eric K Johnson, Scott R Steele 
World J Gastroenterol 20(36):13052-13059. Published online Sep 28, 2014. doi: 10.3748/wjg.v20.i36.13052
Review
Mycobacterium avium subspecies paratuberculosis in the etiology of Crohn’s disease, cause or epiphenomenon? 
Elisa Liverani, Eleonora Scaioli, Carla Cardamone, Paola Dal Monte, Andrea Belluzzi 
World J Gastroenterol 20(36):13060-13070. Published online Sep 28, 2014. doi: 10.3748/wjg.v20.i36.13060
NANOG: A promising target for digestive malignant tumors 
Ai-Xi Sun, Chang-Jiang Liu, Zi-Qin Sun, Zhi Wei 
World J Gastroenterol 20(36):13071-13078. Published online Sep 28, 2014. doi: 10.3748/wjg.v20.i36.13071
Role of Nrf2 in chronic liver disease 
Wei Tang, Yong-Fang Jiang, Murugavel Ponnusamy, Mamadou Diallo 
World J Gastroenterol 20(36):13079-13087. Published online Sep 28, 2014. doi: 10.3748/wjg.v20.i36.13079
Original Article
Osteopontin is an important mediator of alcoholic liver disease via hepatic stellate cell activation 
Devanshi Seth, Alastair Duly, Paul C Kuo, Geoffrey W McCaughan, Paul S Haber 
World J Gastroenterol 20(36):13088-13104. Published online Sep 28, 2014. doi: 10.3748/wjg.v20.i36.13088
Xiaotan Sanjie decoction attenuates tumor angiogenesis by manipulating Notch-1-regulated proliferation of gastric cancer stem-like cells 
Bing Yan, Long Liu, Ying Zhao, Li-Juan Xiu, Da-Zhi Sun, Xuan Liu, Ye Lu, Jun Shi, Yin-Cheng Zhang, Yong-Jin Li, Xiao-Wei Wang, Yu-Qi Zhou, Shou-Han Feng, Can Lv, Pin-Kang Wei, Zhi-Feng Qin 
World J Gastroenterol 20(36):13105-13118. Published online Sep 28, 2014. doi: 10.3748/wjg.v20.i36.13105
Research Report
Reversible immortalization of human hepatocytes mediated by retroviral transfer and site-specific recombination 
Fan-Ying Meng, Li Liu, Feng-Hui Yang, Chun-You Li, Jun Liu, Ping Zhou 
World J Gastroenterol 20(36):13119-13126. Published online Sep 28, 2014. doi: 10.3748/wjg.v20.i36.13119
Case Control Study
Decreased serum platelet derived growth factor BB levels in acute and increased in chronic pancreatitis 
Magdalena Stojek, Krystian Adrych, Lukasz Rojek, Marian Smoczynski, Tomasz Sledzinski, Sylwia Szrok, Julian Swierczynski 
World J Gastroenterol 20(36):13127-13132. Published online Sep 28, 2014. doi: 10.3748/wjg.v20.i36.13127
Small-bowel mucosal injuries in low-dose aspirin users with obscure gastrointestinal bleeding 
Junichi Iwamoto, Yuji Mizokami, Yoshifumi Saito, Koichi Shimokobe, Akira Honda, Tadashi Ikegami, Yasushi Matsuzaki 
World J Gastroenterol 20(36):13133-13138. Published online Sep 28, 2014. doi: 10.3748/wjg.v20.i36.13133
Retrospective Study
Identification of pathologic features associated with “ulcerative colitis-like” Crohn’s disease 
Samuel D James, Paul E Wise, Tania Zuluaga-Toro, David A Schwartz, M Kay Washington, Chanjuan Shi 
World J Gastroenterol 20(36):13139-13145. Published online Sep 28, 2014. doi: 10.3748/wjg.v20.i36.13139
IL28B polymorphism genotyping as predictor of rapid virologic response during interferon plus ribavirin treatment in hepatitis C virus genotype 1 patients 
Chiara Rosso, Maria Lorena Abate, Alessia Ciancio, Silvia Strona, Gian Paolo Caviglia, Antonella Olivero, Giovanni Antonio Touscoz, Mario Rizzetto, Rinaldo Pellicano, Antonina Smedile 
World J Gastroenterol 20(36):13146-13152. Published online Sep 28, 2014. doi: 10.3748/wjg.v20.i36.13146
Repeat endoscopic retrograde cholangiopancreaticography after failed initial precut sphincterotomy for biliary cannulation 
Michael Pavlides, Ashley Barnabas, Nilesh Fernandopulle, Adam A Bailey, Jane Collier, Jane Phillips-Hughes, Anthony Ellis, Roger Chapman, Barbara Braden 
World J Gastroenterol 20(36):13153-13158. Published online Sep 28, 2014. doi: 10.3748/wjg.v20.i36.13153
Risk factors for de novo hepatitis B infection in pediatric living donor liver transplantation 
Wei Rao, Man Xie, Tao Yang, Jian-Jun Zhang, Wei Gao, Yong-Lin Deng, Hong Zheng, Cheng Pan, Yi-He Liu, Zhong-Yang Shen 
World J Gastroenterol 20(36):13159-13166. Published online Sep 28, 2014. doi: 10.3748/wjg.v20.i36.13159
Clinical Trials Study
Preoperative high level of D-dimers predicts unresectability of pancreatic head cancer 
Adam Durczynski, Anna Kumor, Piotr Hogendorf, Dariusz Szymanski, Piotr Grzelak, Janusz Strzelczyk 
World J Gastroenterol 20(36):13167-13171. Published online Sep 28, 2014. doi: 10.3748/wjg.v20.i36.13167
Negative methylation status of Vimentin predicts improved prognosis in pancreatic carcinoma 
Yi-Feng Zhou, Wei Xu, Xia Wang, Jin-Shan Sun, Jing-Jing Xiang, Zhao-Shen Li, Xiao-Feng Zhang 
World J Gastroenterol 20(36):13172-13177. Published online Sep 28, 2014. doi: 10.3748/wjg.v20.i36.13172
Randomized Controlled Trial
Magnetic imaging-assisted colonoscopy vs conventional colonoscopy: A randomized controlled trial 
Christopher W Teshima, Sergio Zepeda-Gómez, Suliman H AlShankiti, Gurpal S Sandha 
World J Gastroenterol 20(36):13178-13184. Published online Sep 28, 2014. doi: 10.3748/wjg.v20.i36.13178
Clinical features, outcomes and treatment-related pneumonitis in elderly patients with esophageal carcinoma 
Jian He, Zhao-Chong Zeng, Shi-Ming Shi, Ping Yang 
World J Gastroenterol 20(36):13185-13190. Published online Sep 28, 2014. doi: 10.3748/wjg.v20.i36.13185
Case Report
Ileal intussusception due to a parasite egg: A case report 
José Pedro Pinto, Agostinho Cordeiro, Ana Margarida Ferreira, Conceição Antunes, Patrícia Botelho, Ana João Rodrigues, Pedro Leão 
World J Gastroenterol 20(36):13191-13194. Published online Sep 28, 2014. doi: 10.3748/wjg.v20.i36.13191
Adrenal lymphangioma masquerading as a pancreatic tail cyst 
Hae Il Jung, Taesung Ahn, Myoung Won Son, Zisun Kim, Sang Ho Bae, Moon Soo Lee, Chang Ho Kim, Hyon Doek Cho 
World J Gastroenterol 20(36):13195-13199. Published online Sep 28, 2014. doi: 10.3748/wjg.v20.i36.13195
Pancreaticojejunostomy, hepaticojejunostomy and double Roux-en-Y digestive tract reconstruction for benign pancreatic diseases 
Chang-Ku Jia, Xue-Fei Lu, Qing-Zhuang Yang, Jie Weng, You-Ke Chen, Yu Fu 
World J Gastroenterol 20(36):13200-13204. Published online Sep 28, 2014. doi: 10.3748/wjg.v20.i36.13200