Clinical impact of minimal cancer cell detection in various colorectal cancer specimens

Table 1 Prognostic value of resectable and metastatic colorectal cancer

Detection method	Objectives	Correlation	Ref.
RT-PCR	Stage I  II III	DFS	[30]
RT-PCR	Stage I  II III	DFS, OS	[31]
RT-PCR	Stage I  II III	RFS	[28]
Immunomagnetic	Stage I  II III	Recurrence	[33]
RT-PCR	Stage I  II III	DFS, OS	[32]
CellSearch	mCRC	PFS, OS	[34]
CellSearch	mCRC	PFS, OS	[35]
CellSearch, RT-PCR	mCRC	OS	[36]
CellSearch	mCRC	PFS, OS	[37]
CellSearch	mCRC	OS	[38]

DFS: Disease-free survival; OS: Overall survival; PFS: Progression-free survival; RT-PCR: Reverse transcriptase polymerase chain reaction; RFS: Recurrence-free survival.