Retrospective Study
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World J Gastroenterol. Sep 21, 2014; 20(35): 12595-12601
Published online Sep 21, 2014. doi: 10.3748/wjg.v20.i35.12595
Preoperative differential diagnosis between intrahepatic biliary cystadenoma and cystadenocarcinoma: A single-center experience
Fu-Bo Zhang, Ai-Min Zhang, Zhi-Bin Zhang, Xin Huang, Xi-Tao Wang, Jia-Hong Dong
Fu-Bo Zhang, Ai-Min Zhang, Zhi-Bin Zhang, Xin Huang, Xi-Tao Wang, Jia-Hong Dong, Department of Hepatobiliary Surgery, Chinese PLA General Hospital, Beijing 100853, China
Fu-Bo Zhang, Ai-Min Zhang, Zhi-Bin Zhang, Xin Huang, Xi-Tao Wang, Jia-Hong Dong, Medical School, Nankai University, Tianjin 300071, China
Ai-Min Zhang, Department of Tuberculosis, Binzhou Center Hospital, Binzhou 251700, Shandong Province, China
Author contributions: Dong JH designed the research; Zhang FB, Zhang AM, Zhang ZB performed the research; Huang X, Wang XT contributed new reagents or analytic tools; Zhang FB, Huang X, Wang XT analyzed the data; Zhang FB, Zhang AM, Zhang ZB, Huang X, Wang XT and Dong JH wrote the paper.
Correspondence to: Jia-Hong Dong, MD, Department of Hepatobiliary Surgery, Chinese PLA General Hospital, 28th Fuxing Rd, Beijing 100853, China. 251809@163.com
Telephone: +86-10-66876432 Fax: +86-10-66876432
Received: March 19, 2014
Revised: May 19, 2014
Accepted: June 14, 2014
Published online: September 21, 2014
Core Tip

Core tip: The number of females was larger than that of males in both groups. Carbohydrate antigen 19-9 has important significance in the preoperative diagnosis of intrahepatic biliary cystadenoma and cystadenocarcinoma. About half of the patients had elevated levels of total bilirubin (TBIL) and direct bilirubin (DBIL); therefore, we believe it is necessary to test TBIL and DBIL before surgery. The diagnosis relies on the integration of information consisting of clinical symptoms, laboratory findings and imaging results. The short-term and long-term prognoses of cystadenoma were better than those for cystadenocarcinoma.