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Open-Access Journal
Editorial
Recent developments in the pathophysiology of irritable bowel syndrome 
Magdy El-Salhy 
World J Gastroenterol 21(25):7621-7636. Published online Jul 7, 2015. doi: 10.3748/wjg.v21.i25.7621
Sarcopenia in the prognosis of cirrhosis: Going beyond the MELD score 
Hee Yeon Kim, Jeong Won Jang 
World J Gastroenterol 21(25):7637-7647. Published online Jul 7, 2015. doi: 10.3748/wjg.v21.i25.7637
Personalized targeted therapy for esophageal squamous cell carcinoma 
Xiaozheng Kang, Keneng Chen, Yicheng Li, Jianying Li, Thomas A D'Amico, Xiaoxin Chen 
World J Gastroenterol 21(25):7648-7658. Published online Jul 7, 2015. doi: 10.3748/wjg.v21.i25.7648
Review
Rectal cancer: An evidence-based update for primary care providers 
Wolfgang B Gaertner, Mary R Kwaan, Robert D Madoff, Genevieve B Melton 
World J Gastroenterol 21(25):7659-7671. Published online Jul 7, 2015. doi: 10.3748/wjg.v21.i25.7659
Gene polymorphisms associated with functional dyspepsia 
Anastasia Kourikou, George P Karamanolis, George D Dimitriadis, Konstantinos Triantafyllou 
World J Gastroenterol 21(25):7672-7682. Published online Jul 7, 2015. doi: 10.3748/wjg.v21.i25.7672
Primary biliary cirrhosis: Clinical and laboratory criteria for its diagnosis 
Vasiliy Ivanovich Reshetnyak 
World J Gastroenterol 21(25):7683-7708. Published online Jul 7, 2015. doi: 10.3748/wjg.v21.i25.7683
Minireviews
Geographic differences in low-dose aspirin-associated gastroduodenal mucosal injury 
Katsunori Iijima, Tooru Shimosegawa 
World J Gastroenterol 21(25):7709-7717. Published online Jul 7, 2015. doi: 10.3748/wjg.v21.i25.7709
Basic Study
Hepatoprotective effect of Geranium schiedeanum against ethanol toxicity during liver regeneration 
Eduardo Madrigal-Santillán, Mirandeli Bautista, Juan A Gayosso-De-Lucio, Yadira Reyes-Rosales, Araceli Posadas-Mondragón, Ángel Morales-González, Marvin A Soriano-Ursúa, Jazmín García-Machorro, Eduardo Madrigal-Bujaidar, Isela Álvarez-González, José A Morales-González 
World J Gastroenterol 21(25):7718-7729. Published online Jul 7, 2015. doi: 10.3748/wjg.v21.i25.7718
TLR2 and TLR4 polymorphisms influence mRNA and protein expression in colorectal cancer 
Marcela Alcântara Proença, Juliana Garcia de Oliveira, Aline Cristina Targa Cadamuro, Maysa Succi, João Gomes Netinho, Eny Maria Goloni-Bertolo, Érika Cristina Pavarino, Ana Elizabete Silva 
World J Gastroenterol 21(25):7730-7741. Published online Jul 7, 2015. doi: 10.3748/wjg.v21.i25.7730
Effect of endogenous cholecystokinin on the course of acute pancreatitis in rats 
Dongmei Jia, Mitsuyoshi Yamamoto, Makoto Otsuki 
World J Gastroenterol 21(25):7742-7753. Published online Jul 7, 2015. doi: 10.3748/wjg.v21.i25.7742
Ezetimibe improves hepatic steatosis in relation to autophagy in obese and diabetic rats 
Eugene Chang, Lisa Kim, Se Eun Park, Eun-Jung Rhee, Won-Young Lee, Ki-Won Oh, Sung-Woo Park, Cheol-Young Park 
World J Gastroenterol 21(25):7754-7763. Published online Jul 7, 2015. doi: 10.3748/wjg.v21.i25.7754
Overexpression of HMGB1 A-box reduced lipopolysaccharide-induced intestinal inflammation via HMGB1/TLR4 signaling in vitro 
Fu-Cai Wang, Jing-Xuan Pei, Jun Zhu, Nan-Jin Zhou, Dong-Sheng Liu, Hui-Fang Xiong, Xiao-Qun Liu, Dong-Jia Lin, Yong Xie 
World J Gastroenterol 21(25):7764-7776. Published online Jul 7, 2015. doi: 10.3748/wjg.v21.i25.7764
Berberine inhibits hepatic gluconeogenesis via the LKB1-AMPK-TORC2 signaling pathway in streptozotocin-induced diabetic rats 
Shu-Jun Jiang, Hui Dong, Jing-Bin Li, Li-Jun Xu, Xin Zou, Kai-Fu Wang, Fu-Er Lu, Ping Yi 
World J Gastroenterol 21(25):7777-7785. Published online Jul 7, 2015. doi: 10.3748/wjg.v21.i25.7777
Case Control Study
NOD2/CARD15 gene mutations in North Algerian patients with inflammatory bowel disease 
Aziza Boukercha, Hamida Mesbah-Amroun, Amira Bouzidi, Houria Saoula, Mhamed Nakkemouche, Maryline Roy, Jean-Pierre Hugot, Chafia Touil-Boukoffa 
World J Gastroenterol 21(25):7786-7794. Published online Jul 7, 2015. doi: 10.3748/wjg.v21.i25.7786
Retrospective Cohort Study
Clinical predictors of thiopurine-related adverse events in Crohn's disease 
Gordon W Moran, Marie-France Dubeau, Gilaad G Kaplan, Hong Yang, Bertus Eksteen, Subrata Ghosh, Remo Panaccione 
World J Gastroenterol 21(25):7795-7804. Published online Jul 7, 2015. doi: 10.3748/wjg.v21.i25.7795
Retrospective Study
Gastric cancer in women: A regional health-center seven year retrospective study 
Kunal Suryawala, Demiana Soliman, Monica Mutyala, Shaheen Nageeb, Moheb Boktor, Abhishek Seth, Avinash Aravantagi, Ankur Sheth, James Morris, Paul Jordan, Kenneth Manas, Urska Cvek, Marjan Trutschl, Felix Becker, Jonathan Alexander 
World J Gastroenterol 21(25):7805-7813. Published online Jul 7, 2015. doi: 10.3748/wjg.v21.i25.7805
miR-122 negatively correlates with liver fibrosis as detected by histology and FibroScan 
Tünde Halász, Gábor Horváth, Gabriella Pár, Klára Werling, András Kiss, Zsuzsa Schaff, Gábor Lendvai 
World J Gastroenterol 21(25):7814-7823. Published online Jul 7, 2015. doi: 10.3748/wjg.v21.i25.7814
Gd-EOB-DTPA-enhanced magnetic resonance imaging for bile duct intraductal papillary mucinous neoplasms 
Shi-Hong Ying, Xiao-Dong Teng, Zhao-Ming Wang, Qi-Dong Wang, Yi-Lei Zhao, Feng Chen, Wen-Bo Xiao 
World J Gastroenterol 21(25):7824-7833. Published online Jul 7, 2015. doi: 10.3748/wjg.v21.i25.7824
When and why a colonoscopist should discontinue colonoscopy by himself? 
Tao Gan, Jin-Lin Yang, Jun-Chao Wu, Yi-Ping Wang, Li Yang 
World J Gastroenterol 21(25):7834-7841. Published online Jul 7, 2015. doi: 10.3748/wjg.v21.i25.7834
Observational Study
Seroepidemiology of hepatitis B virus infection and impact of vaccination 
Peng Huang, Li-Guo Zhu, Ye-Fei Zhu, Ming Yue, Jing Su, Feng-Cai Zhu, Hai-Tao Yang, Yun Zhang, Hong-Bing Shen, Rong-Bin Yu, Xiang-Jun Zhai, Zhi-Hang Peng 
World J Gastroenterol 21(25):7842-7850. Published online Jul 7, 2015. doi: 10.3748/wjg.v21.i25.7842
Prospective Study
Tissue resonance interaction accurately detects colon lesions: A double-blind pilot study 
Maria P Dore, Marcello O Tufano, Giovanni M Pes, Marianna Cuccu, Valentina Farina, Alessandra Manca, David Y Graham 
World J Gastroenterol 21(25):7851-7859. Published online Jul 7, 2015. doi: 10.3748/wjg.v21.i25.7851
Resolution of non-alcoholic steatohepatitis by rosuvastatin monotherapy in patients with metabolic syndrome 
Konstantinos Kargiotis, Vasilios G Athyros, Olga Giouleme, Niki Katsiki, Evangelia Katsiki, Panagiotis Anagnostis, Chrysoula Boutari, Michael Doumas, Asterios Karagiannis, Dimitri P Mikhailidis 
World J Gastroenterol 21(25):7860-7868. Published online Jul 7, 2015. doi: 10.3748/wjg.v21.i25.7860
Long-term antiviral efficacy of entecavir and liver histology improvement in Chinese patients with hepatitis B virus-related cirrhosis 
Yan Xu, Yong-Gui Zhang, Xu Wang, Wen-Qian Qi, Shao-You Qin, Zhen-Hua Liu, Jian Jiao, Jiang-Bin Wang 
World J Gastroenterol 21(25):7869-7876. Published online Jul 7, 2015. doi: 10.3748/wjg.v21.i25.7869
Systematic Reviews
Utility of fluorescent cholangiography during laparoscopic cholecystectomy: A systematic review 
Antonio Pesce, Gaetano Piccolo, Gaetano La Greca, Stefano Puleo 
World J Gastroenterol 21(25):7877-7883. Published online Jul 7, 2015. doi: 10.3748/wjg.v21.i25.7877
Meta-Analysis
Diagnostic performance of magnifying narrow-band imaging for early gastric cancer: A meta-analysis 
Ying-Ying Hu, Qing-Wu Lian, Zheng-Hua Lin, Jing Zhong, Meng Xue, Liang-Jing Wang 
World J Gastroenterol 21(25):7884-7894. Published online Jul 7, 2015. doi: 10.3748/wjg.v21.i25.7884
Thrombocytopenia for prediction of hepatocellular carcinoma recurrence: Systematic review and meta-analysis 
Qing Pang, Kai Qu, Jian-Bin Bi, Su-Shun Liu, Jing-Yao Zhang, Si-Dong Song, Ting Lin, Xin-Sen Xu, Yong Wan, Ming-Hui Tai, Hao-Chen Liu, Ya-Feng Dong, Chang Liu 
World J Gastroenterol 21(25):7895-7906. Published online Jul 7, 2015. doi: 10.3748/wjg.v21.i25.7895
Case Report
Endovascular treatment of post-laparoscopic pancreatectomy splenic arteriovenous fistula with splenic vein aneurysm 
Tatsuo Ueda, Satoru Murata, Akira Yamamoto, Jin Tamai, Yuko Kobayashi, Chiaki Hiranuma, Hiroshi Yoshida, Shin-ichiro Kumita 
World J Gastroenterol 21(25):7907-7910. Published online Jul 7, 2015. doi: 10.3748/wjg.v21.i25.7907
Helicobacter cinaedi bacteremia with cellulitis after ABO-incompatible living-donor liver transplantation: Case report 
Kohei Mishima, Hideaki Obara, Kayoko Sugita, Masahiro Shinoda, Minoru Kitago, Yuta Abe, Taizo Hibi, Hiroshi Yagi, Kentaro Matsubara, Takehiko Mori, Yaoko Takano, Hiroshi Fujiwara, Osamu Itano, Naoki Hasegawa, Satoshi Iwata, Yuko Kitagawa 
World J Gastroenterol 21(25):7911-7915. Published online Jul 7, 2015. doi: 10.3748/wjg.v21.i25.7911
Intraductal papillary mucinous neoplasm of the ileal heterotopic pancreas in a patient with hereditary non-polyposis colorectal cancer: A case report 
Sang Hwa Lee, Wook Youn Kim, Dae-Yong Hwang, Hye Seung Han 
World J Gastroenterol 21(25):7916-7920. Published online Jul 7, 2015. doi: 10.3748/wjg.v21.i25.7916
Monitoring disease progression and treatment efficacy with circulating tumor cells in esophageal squamous cell carcinoma: A case report 
Yuan-Yuan Qiao, Kai-Xuan Lin, Ze Zhang, Da-Jin Zhang, Cheng-He Shi, Ming Xiong, Xiu-Hua Qu, Xiao-Hang Zhao 
World J Gastroenterol 21(25):7921-7928. Published online Jul 7, 2015. doi: 10.3748/wjg.v21.i25.7921
Refractory diarrhea: A paraneoplastic syndrome of neuroblastoma 
Wei Han, Huan-Min Wang 
World J Gastroenterol 21(25):7929-7932. Published online Jul 7, 2015. doi: 10.3748/wjg.v21.i25.7929