Boukercha A, Mesbah-Amroun H, Bouzidi A, Saoula H, Nakkemouche M, Roy M, Hugot JP, Touil-Boukoffa C. NOD2/CARD15 gene mutations in North Algerian patients with inflammatory bowel disease. World J Gastroenterol 2015; 21(25): 7786-7794 [PMID: 26167078 DOI: 10.3748/wjg.v21.i25.7786]
Corresponding Author of This Article
Hamida Mesbah-Amroun, PhD, Laboratory of Cellular and Molecular Biology, Faculty of Biological Sciences, University of Sciences and Technology Houari Boumediene, BP32, Bab-Ezzouar, Algiers 16111, Algeria. email@example.com
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4The P value for UC patients vs HC group. (%) represents allele frequency. CD: Crohn's disease; UC: Ulcerative colitis; IBD: İnflammatory bowel disease (CD + UC patients); HC: Healthy controls; WT: Wild type allele; insC: Insertion mutation of a C.
Table 4 Number of different genotypes observed in Crohn's disease/ulcerative colitis/healthy controls groups
In each cell of the table, the genotype is obtained by combining the two genetic variants indicated in the corresponding row and column. No patients homozygous for NOD2 gene p.Gly908Arg and p.Leu1007fsinsC mutations were found in this study. CD: Crohn's disease; UC: Ulcerative colitis; HC: Healthy controls; WT: Wild type.
Table 5 Hardy-Weinberg equilibrium and the P value
CD: Crohn's disease; HC: Healthy controls; IBD: İnflammatory bowel disease; NS: Non-significant P value; WT: Wild type; insC: Insertion mutation of a C.
Table 6 Comparative study of NOD2 allele frequencies in North African populations
CD: Crohn's disease; HC: Healthy controls; ND: Not determined.
Citation: Boukercha A, Mesbah-Amroun H, Bouzidi A, Saoula H, Nakkemouche M, Roy M, Hugot JP, Touil-Boukoffa C. NOD2/CARD15 gene mutations in North Algerian patients with inflammatory bowel disease. World J Gastroenterol 2015; 21(25): 7786-7794