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©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Jul 7, 2015; 21(25): 7824-7833
Published online Jul 7, 2015. doi: 10.3748/wjg.v21.i25.7824
Published online Jul 7, 2015. doi: 10.3748/wjg.v21.i25.7824
Gd-EOB-DTPA-enhanced magnetic resonance imaging for bile duct intraductal papillary mucinous neoplasms
Shi-Hong Ying, Qi-Dong Wang, Yi-Lei Zhao, Feng Chen, Wen-Bo Xiao, Department of Radiology, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou 310003, Zhejiang Province, China
Xiao-Dong Teng, Zhao-Ming Wang, Department of Pathology, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou 310003, Zhejiang Province, China
Author contributions: Ying SH, Chen F and Xiao WB designed the research; Ying SH, Teng XD and Wang QD performed the research; Wang ZM and Zhao YL analyzed the data; Ying SH, Chen F and Xiao WB wrote the paper; all authors approved the final version for publication.
Supported by National Natural Science Foundation of China, No. 81171388; and Ministry of Health Research Foundation of China (in part), No. WKJ2011-2-004.
Ethics approval: The study was a retrospective study, and every patient had undergone ethoxybenzyl-enhanced magnetic resonance imaging according to clinical routine.
Informed consent statement: Informed written consent was obtained from all patients.
Conflict-of-interest statement: Authors have no conflicts of interest for this paper.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Wen-Bo Xiao, MD, Chief Doctor, Department of Radiology, The First Affiliated Hospital, College of Medicine, Zhejiang University, No. 79 Qingchun Road, Hangzhou 310003, Zhejiang Province, China. xiaowb.111@163.com
Telephone: +86-571-87236587 Fax: +86-571-87236587
Received: December 14, 2014
Peer-review started: December 18, 2014
First decision: January 22, 2015
Revised: February 20, 2015
Accepted: April 17, 2015
Article in press: April 17, 2015
Published online: July 7, 2015
Peer-review started: December 18, 2014
First decision: January 22, 2015
Revised: February 20, 2015
Accepted: April 17, 2015
Article in press: April 17, 2015
Published online: July 7, 2015
Core Tip
Core tip: Gadolinium-ethoxybenzyl-diethylenetriamine-pentaacetic acid (Gd-EOB-DTPA)-enhanced magnetic resonance imaging (MRI) can be used to demonstrate the filling defects due to mucin secreted by intraductal papillary mucinous neoplasms of the bile duct (IPMN-B) and to display the extent of tumor infiltration beyond bile ducts in cases with invasive IPMN-B. It also has the potential to differentiate tumor tissue from inflammatory lesions. Therefore, Gd-EOB-DTPA-enhanced MRI may improve the clinical management of IPMN-B.