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©2014 Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Sep 28, 2014; 20(36): 12781-12808
Published online Sep 28, 2014. doi: 10.3748/wjg.v20.i36.12781
Published online Sep 28, 2014. doi: 10.3748/wjg.v20.i36.12781
Beyond the stomach: An updated view of Helicobacter pylori pathogenesis, diagnosis, and treatment
Traci L Testerman, Department of Microbiology and Immunology, Uniformed Services University of the Health Sciences, Bethesda, MD 20814, United States
James Morris, Department of Gastroenterology, Louisiana State University Health Sciences Center-Shreveport, Shreveport, LA 71130, United States
Author contributions: Testerman TL and Morris J solely contributed to this manuscript.
Correspondence to: Traci L Testerman, PhD, Department of Microbiology and Immunology, Uniformed Services University of the Health Sciences, 4301 Jones Bridge Rd, Bethesda, MD 20814, United States. t.testerman01@gmail.com
Telephone: +1-318-7511267 Fax: +1-301-2953773
Received: December 17, 2013
Revised: April 17, 2014
Accepted: June 20, 2014
Published online: September 28, 2014
Revised: April 17, 2014
Accepted: June 20, 2014
Published online: September 28, 2014
Core Tip
Core tip:Helicobacter pylori (H. pylori) infection remains a common cause of morbidity and mortality. Evidence for additional H. pylori-mediated diseases, as well as potentially beneficial effects of H. pylori infection, complicates decisions regarding when testing for and treating of H. pylori infections is appropriate. In the meantime, eradication of H. pylori is becoming more difficult due to increasing antibiotic resistance. This review summarizes recent findings on H. pylori pathogenesis, testing, and treatment.