Randomized Controlled Trial
Copyright ©2014 Baishideng Publishing Group Inc.
World J Gastroenterol. Sep 28, 2014; 20(36): 13178-13184
Published online Sep 28, 2014. doi: 10.3748/wjg.v20.i36.13178
Table 1 Patient characteristics n (%)
CharacteristicsConventional colonoscopy(n = 122)Magnetic imaging colonoscopy(n = 131)Total(n = 253)
Age (yr, range)58.2 (18-82)57.7 (19-86)57.9 (18-86)
Gender-male63 (51.6)68 (51.9)131 (51.8)
Previous colonoscopy77 (63.1)66 (50.4)143 (56.5)
Prior abdo or pelvic surgery19 (15.6)26 (19.9)45 (17.8)
Indication
Screening or polyp follow-up71 (58.2)79 (60.3)150 (59.3)
GI bleeding13 (10.7)23 (17.6)36 (14.2)
Anemia or FOBT+7 (5.7)10 (7.6)17 (6.7)
Diarrhea5 (4.1)11 (8.4)16 (6.3)
IBD8 (6.6)4 (3.1)12 (4.7)
Other18 (14.8)4 (3.1)22 (8.7)
Table 2 Endoscopic outcomes
Endoscopic outcomesConventional colonoscopy(n = 122)Magnetic imaging colonoscopy(n = 131)Total(n = 253)P value
Cecal intubation n (%)121 (99.2)131 (100)252 (99.6)0.30
TI intubation n (%)42 (34.4)46 (35.1)88 (34.8)0.91
Distance to cecum (cm)83 (53–130)82.4 (49–150)82.7 (49–150)0.71
Time-to-cecum (min)7.2 (2-29.5)6.5 (1.2-28)6.9 (1.2-29.5)0.18
Total procedure time (min)16.7 (8.1-36)15.7 (5.7-40)16.2 (5.7-40)0.19
Polyp detection rate51.60% (0.43, 0.61)46.60% (0.38, 0.55)49.0%0.42
Meanpolyps (range)1.7 (1-7)1.9 (1-8)1.8 (1-8)0.36
Quality of bowel prep
Excellent21.3%29.8%25.7%
Acceptable49.2%43.5%46.3%
Fair25.4%24.4%24.9%
Poor4.1%2.3%3.2%
Procedures self-rated as “difficult”n (%)25 (20.5)36 (27.5)61 (24.1)0.19
Sedation, mean doses (range)
Midazolam (mg)5.8 (3-15)5.5 (2-15)5.7 (2-15)0.31
Fentanyl (mcg)86.3 (50-150)83.2 (50-150)84.7 (50-150)0.29
Table 3 Patient experience outcomes
ScoreConventional colonoscopy(n = 122)Magnetic imaging colonoscopy(n = 131)Total(n = 253)P value
Pain score0.85 (0.1-8.4)1.03 (0.1-10)0.94 (0.1-10)0.41
Pretest pain score2.2 (0.1-8.5)2.9 (0.1-9)2.5 (0.1-9)0.02
Pain difference-1.3-1.8-1.60.14
Sedation score8.5 (4.5-17)8.2 (4-21)8.3 (4-21)0.34
Table 4 Subgroup of self-rated “difficult” colonoscopy procedures
Colonoscopy proceduresConventional colonoscopy(n = 25)Magnetic imaging colonoscopy(n = 36)Total(n = 61)P value
Time-to-cecum (min)13.410.1011.500.01
(6.7-29.5)(3.8-28)(3.8-29.5)
Distance to cecum (cm)91.2085.70880.30
(68-130)(49-150)(49-150)
Sedation score9.549.089.270.61
(5-17)(5-21)(5-21)
Pain score1.481.151.280.53
(0.1-8.4)(0.1-7.9)(0.1-8.4)
Pain difference-1.05-1.50-1.320.54
(-6.8-3.3)(-7.8-4.9)(-7.8-4.9)