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World J Gastroenterol. Sep 28, 2014; 20(36): 12818-12838
Published online Sep 28, 2014. doi: 10.3748/wjg.v20.i36.12818
Published online Sep 28, 2014. doi: 10.3748/wjg.v20.i36.12818
Hematologic manifestations of Helicobacter pylori infection
Germán Campuzano-Maya, Group of Clinical Pathology, Laboratorio Clínico Hematológico, Faculty of Medicine, University of Antioquia, 53108 Medellín, Colombia
Author contributions: Campuzano-Maya G solely contributed to this manuscript.
Correspondence to: Germán Campuzano-Maya, MD, Group of Clinical Pathology, Laboratorio Clínico Hematológico, Faculty of Medicine, University of Antioquia, Carrera 43C No. 5-33, 53108 Medellín, Colombia. gcm@lch.co
Telephone: +57-4-4444200 Fax: +57-4-3128232
Received: May 3, 2014
Revised: June 10, 2014
Accepted: July 16, 2014
Published online: September 28, 2014
Revised: June 10, 2014
Accepted: July 16, 2014
Published online: September 28, 2014
Core Tip
Core tip:Helicobacter pylori (H. pylori) infections are intimately related to malignant gastric condictions and benign diseases in the stomach, nevertheless there are extragastric manifestations closely related with H. pylori infection. This review focuses on hematologic diseases included in international consensus and management guides for H. pylori infection; specifically iron deficiency, vitamin B12 (cobalamin) deficiency, immune thrombocytopenia, and extranodal marginal zone mucosa-associated lymphoid tissue lymphoma. In addition of other hematologic diseases not included in guides and consensus as auto-immune neutropenia, antiphospholipid syndrome, and plasma cell dyscrasias.