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High Impact Articles
High impact papers are those to which special attention is paid by experts in the given field, with a large number of visitors, frequent downloads and higher citation rates. The research must be creative, with high academic standards and have a wide influence, if it is to become a high impact paper. They are ranked by the number of downloads.
Rank Full Article
1
Update on the treatment of type 2 diabetes mellitus  
Juan José Marín-Peñalver, Iciar Martín-Timón, Cristina Sevillano-Collantes, Francisco Javier del Cañizo-Gómez 
World J Diabetes 7(17):354-395. Published online Sep 15, 2016. doi: 10.4239/wjd.v7.i17.354
2
3
Literature review on the management of diabetic foot ulcer  
Leila Yazdanpanah, Morteza Nasiri, Sara Adarvishi 
World J Diabetes 6(1):37-53. Published online Feb 15, 2015. doi: 10.4239/wjd.v6.i1.37
4
Oxidative stress, insulin resistance, dyslipidemia and type 2 diabetes mellitus  
Surapon Tangvarasittichai 
World J Diabetes 6(3):456-480. Published online Apr 15, 2015. doi: 10.4239/wjd.v6.i3.456
5
Adiponectin: Probe of the molecular paradigm associating diabetes and obesity  
Kakali Ghoshal, Maitree Bhattacharyya 
World J Diabetes 6(1):151-166. Published online Feb 15, 2015. doi: 10.4239/wjd.v6.i1.151
6
Short acting insulin analogues in intensive care unit patients  
Federico Bilotta, Carolina Guerra, Rafael Badenes, Simona Lolli, Giovanni Rosa 
World J Diabetes 5(3):230-234. Published online Jun 15, 2014. doi: 10.4239/wjd.v5.i3.230
7
8
Diabetic foot disease: From the evaluation of the “foot at risk” to the novel diabetic ulcer treatment modalities  
Noha Amin, John Doupis 
World J Diabetes 7(7):153-164. Published online Apr 10, 2016. doi: 10.4239/wjd.v7.i7.153
9
Association of obesity with hypertension and type 2 diabetes mellitus in India: A meta-analysis of observational studies  
Giridhara R Babu, G V S Murthy, Yamuna Ana, Prital Patel, R Deepa, Sara E Benjamin-Neelon, Sanjay Kinra, K Srinath Reddy 
World J Diabetes 9(1):40-52. Published online Jan 15, 2018. doi: 10.4239/wjd.v9.i1.40
10
11
Milestones in the history of diabetes mellitus: The main contributors  
Marianna Karamanou, Athanase Protogerou, Gregory Tsoucalas, George Androutsos, Effie Poulakou-Rebelakou 
World J Diabetes 7(1):1-7. Published online Jan 10, 2016. doi: 10.4239/wjd.v7.i1.1
12
Diabetes and cardiovascular disease: Epidemiology, biological mechanisms, treatment recommendations and future research  
Benjamin M Leon, Thomas M Maddox 
World J Diabetes 6(13):1246-1258. Published online Oct 10, 2015. doi: 10.4239/wjd.v6.i13.1246
13
Effects of diabetic ketoacidosis in the respiratory system  
Alice Gallo de Moraes, Salim Surani 
World J Diabetes 10(1):16-22. Published online Jan 15, 2019. doi: 10.4239/wjd.v10.i1.16
14
Type 2 diabetes and cardiovascular disease: Have all risk factors the same strength?  
Iciar Martín-Timón, Cristina Sevillano-Collantes, Amparo Segura-Galindo, Francisco Javier del Cañizo-Gómez 
World J Diabetes 5(4):444-470. Published online Aug 15, 2014. doi: 10.4239/wjd.v5.i4.444
15
Effects of intermittent fasting on health markers in those with type 2 diabetes: A pilot study  
Terra G Arnason, Matthew W Bowen, Kerry D Mansell 
World J Diabetes 8(4):154-164. Published online Apr 15, 2017. doi: 10.4239/wjd.v8.i4.154
16
Role of vitamin D in diabetes mellitus and chronic kidney disease  
Akio Nakashima, Keitaro Yokoyama, Takashi Yokoo, Mitsuyoshi Urashima 
World J Diabetes 7(5):89-100. Published online Mar 10, 2016. doi: 10.4239/wjd.v7.i5.89
17
Gestational diabetes: A clinical update  
Ulla Kampmann, Lene Ring Madsen, Gitte Oeskov Skajaa, Ditte Smed Iversen, Niels Moeller, Per Ovesen 
World J Diabetes 6(8):1065-1072. Published online Jul 25, 2015. doi: 10.4239/wjd.v6.i8.1065
18
19
20
Relationship between diabetes and periodontal infection  
Fernando Llambés, Santiago Arias-Herrera, Raúl Caffesse 
World J Diabetes 6(7):927-935. Published online Jul 10, 2015. doi: 10.4239/wjd.v6.i7.927
21
Nutrition, insulin resistance and dysfunctional adipose tissue determine the different components of metabolic syndrome  
Juan Antonio Paniagua 
World J Diabetes 7(19):483-514. Published online Nov 15, 2016. doi: 10.4239/wjd.v7.i19.483
22
Gut-brain connection: The neuroprotective effects of the anti-diabetic drug liraglutide  
Emanuel Monteiro Candeias, Inês Carolina Sebastião, Susana Maria Cardoso, Sónia Catarina Correia, Cristina Isabel Carvalho, Ana Isabel Plácido, Maria Sancha Santos, Catarina Resende Oliveira, Paula Isabel Moreira, Ana Isabel Duarte 
World J Diabetes 6(6):807-827. Published online Jun 25, 2015. doi: 10.4239/wjd.v6.i6.807
23
Use of sodium bicarbonate and blood gas monitoring in diabetic ketoacidosis: A review  
Mit P Patel, Ali Ahmed, Tharini Gunapalan, Sean E Hesselbacher 
World J Diabetes 9(11):199-205. Published online Nov 15, 2018. doi: 10.4239/wjd.v9.i11.199
24
Type 2 diabetes and quality of life  
Aikaterini Trikkalinou, Athanasia K Papazafiropoulou, Andreas Melidonis 
World J Diabetes 8(4):120-129. Published online Apr 15, 2017. doi: 10.4239/wjd.v8.i4.120
25
26
Steroid hyperglycemia: Prevalence, early detection and therapeutic recommendations: A narrative review  
Héctor Eloy Tamez-Pérez, Dania Lizet Quintanilla-Flores, René Rodríguez-Gutiérrez, José Gerardo González-González, Alejandra Lorena Tamez-Peña 
World J Diabetes 6(8):1073-1081. Published online Jul 25, 2015. doi: 10.4239/wjd.v6.i8.1073
27
Effect of medicinal mushrooms on blood cells under conditions of diabetes mellitus  
Taras Vitak, Borys Yurkiv, Solomon Wasser, Eviatar Nevo, Natalia Sybirna 
World J Diabetes 8(5):187-201. Published online May 15, 2017. doi: 10.4239/wjd.v8.i5.187
28
Diabetic neuropathic pain: Physiopathology and treatment  
Anne K Schreiber, Carina FM Nones, Renata C Reis, Juliana G Chichorro, Joice M Cunha 
World J Diabetes 6(3):432-444. Published online Apr 15, 2015. doi: 10.4239/wjd.v6.i3.432
29
Role of bile acids in the regulation of the metabolic pathways  
Hiroki Taoka, Yoko Yokoyama, Kohkichi Morimoto, Naho Kitamura, Tatsuya Tanigaki, Yoko Takashina, Kazuo Tsubota, Mitsuhiro Watanabe 
World J Diabetes 7(13):260-270. Published online Jul 10, 2016. doi: 10.4239/wjd.v7.i13.260
30
Psychological aspects of diabetes care: Effecting behavioral change in patients  
Boon-How Chew, Sazlina Shariff-Ghazali, Aaron Fernandez 
World J Diabetes 5(6):796-808. Published online Dec 15, 2014. doi: 10.4239/wjd.v5.i6.796
31
Whey protein: The “whey” forward for treatment of type 2 diabetes?  
Linda E Mignone, Tongzhi Wu, Michael Horowitz, Christopher K Rayner 
World J Diabetes 6(14):1274-1284. Published online Oct 25, 2015. doi: 10.4239/wjd.v6.i14.1274
32
Molecular and biochemical trajectories from diabetes to Alzheimer’s disease: A critical appraisal  
Rajat Sandhir, Smriti Gupta 
World J Diabetes 6(12):1223-1242. Published online Sep 25, 2015. doi: 10.4239/wjd.v6.i12.1223
33
Leucine signaling in the pathogenesis of type 2 diabetes and obesity  
Bodo C Melnik 
World J Diabetes 3(3):38-53. Published online Mar 15, 2012. doi: 10.4239/wjd.v3.i3.38
34
Diabetic retinopathy - ocular complications of diabetes mellitus  
Martin M Nentwich, Michael W Ulbig 
World J Diabetes 6(3):489-499. Published online Apr 15, 2015. doi: 10.4239/wjd.v6.i3.489
35
Type 2 diabetes mellitus in children and adolescents  
Thomas Reinehr 
World J Diabetes 4(6):270-281. Published online Dec 15, 2013. doi: 10.4239/wjd.v4.i6.270
36
Trends in prevalence of diabetes in Asian countries  
Ambady Ramachandran, Chamukuttan Snehalatha, Ananth Samith Shetty, Arun Nanditha 
World J Diabetes 3(6):110-117. Published online Jun 15, 2012. doi: 10.4239/wjd.v3.i6.110
37
Mechanisms of hypoglycemia unawareness and implications in diabetic patients  
Iciar Martín-Timón, Francisco Javier del Cañizo-Gómez 
World J Diabetes 6(7):912-926. Published online Jul 10, 2015. doi: 10.4239/wjd.v6.i7.912
38
Biomolecular basis of the role of diabetes mellitus in osteoporosis and bone fractures  
Bipradas Roy 
World J Diabetes 4(4):101-113. Published online Aug 15, 2013. doi: 10.4239/wjd.v4.i4.101
39
Social determinants of type 2 diabetes and health in the United States  
Myra L Clark, Sharon W Utz 
World J Diabetes 5(3):296-304. Published online Jun 15, 2014. doi: 10.4239/wjd.v5.i3.296
40
41
Type 2 diabetes mellitus: From a metabolic disorder to an inflammatory condition  
Iqra Hameed, Shariq R Masoodi, Shahnaz A Mir, Mudasar Nabi, Khalid Ghazanfar, Bashir A Ganai 
World J Diabetes 6(4):598-612. Published online May 15, 2015. doi: 10.4239/wjd.v6.i4.598
42
Gestational diabetes mellitus: Challenges for different ethnic groups  
Lili Yuen, Vincent W Wong 
World J Diabetes 6(8):1024-1032. Published online Jul 25, 2015. doi: 10.4239/wjd.v6.i8.1024
43
Cardiac autonomic neuropathy in patients with diabetes mellitus  
Gerasimos Dimitropoulos, Abd A Tahrani, Martin J Stevens 
World J Diabetes 5(1):17-39. Published online Feb 15, 2014. doi: 10.4239/wjd.v5.i1.17
44
Hyporeninemic hypoaldosteronism and diabetes mellitus: Pathophysiology assumptions, clinical aspects and implications for management  
André Gustavo P Sousa, João Victor de Sousa Cabral, William Batah El-Feghaly, Luísa Silva de Sousa, Adriana Bezerra Nunes 
World J Diabetes 7(5):101-111. Published online Mar 10, 2016. doi: 10.4239/wjd.v7.i5.101
45
Causative anti-diabetic drugs and the underlying clinical factors for hypoglycemia in patients with diabetes  
Hidekatsu Yanai, Hiroki Adachi, Hisayuki Katsuyama, Sumie Moriyama, Hidetaka Hamasaki, Akahito Sako 
World J Diabetes 6(1):30-36. Published online Feb 15, 2015. doi: 10.4239/wjd.v6.i1.30
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47
Pharmacogenetic studies update in type 2 diabetes mellitus  
Shalini Singh, Kauser Usman, Monisha Banerjee 
World J Diabetes 7(15):302-315. Published online Aug 10, 2016. doi: 10.4239/wjd.v7.i15.302
48
Choice of wound care in diabetic foot ulcer: A practical approach  
Karakkattu Vijayan Kavitha, Shalbha Tiwari, Vedavati Bharat Purandare, Sudam Khedkar, Shilpa Sameer Bhosale, Ambika Gopalakrishnan Unnikrishnan 
World J Diabetes 5(4):546-556. Published online Aug 15, 2014. doi: 10.4239/wjd.v5.i4.546
49
Glucagon-like peptide 1 in the pathophysiology and pharmacotherapy of clinical obesity  
Ananthi Anandhakrishnan, Márta Korbonits 
World J Diabetes 7(20):572-598. Published online Dec 15, 2016. doi: 10.4239/wjd.v7.i20.572
50
Bariatric surgery and long-term nutritional issues  
Roberta Lupoli, Erminia Lembo, Gennaro Saldalamacchia, Claudia Kesia Avola, Luigi Angrisani, Brunella Capaldo 
World J Diabetes 8(11):464-474. Published online Nov 15, 2017. doi: 10.4239/wjd.v8.i11.464