Genetics of type 2 diabetes

doi:10.4239/wjd.v4.i4.114

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Aug 15, 2013 (publication date) through Apr 22, 2024

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World Journal of Diabetes

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1948-9358

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Diabetes. Aug 15, 2013; 4(4): 114-123
Published online Aug 15, 2013. doi: 10.4239/wjd.v4.i4.114

Genetics of type 2 diabetes

Omar Ali

Omar Ali, Medical College of Wisconsin, Milwaukee, WI 53226, United States

Author contributions: Ali O reviewed the published literature and wrote the article in its entirety.

Correspondence to: Omar Ali, MD, Medical College of Wisconsin, Milwaukee, 8701 W Watertown Plank Rd, WI 53226, United States. oali@mcw.edu

Telephone: +1-414-2666750 Fax: +1-414-2666749

Received: March 3, 2013
Revised: June 1, 2013
Accepted: July 18, 2013
Published online: August 15, 2013

Core Tip

Core tip: We review the history and the current state of knowledge regarding the genetic component of type 2 diabetes risk. Genes like TCF7L2 that have been replicated in multiple studies are discussed in detail. The significance of these findings is discussed and gaps in our knowledge are identified, as are avenues for future research.