Review
Copyright ©The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Diabetes. May 15, 2017; 8(5): 187-201
Published online May 15, 2017. doi: 10.4239/wjd.v8.i5.187
Effect of medicinal mushrooms on blood cells under conditions of diabetes mellitus
Taras Vitak, Borys Yurkiv, Solomon Wasser, Eviatar Nevo, Natalia Sybirna
Taras Vitak, Borys Yurkiv, Department of Evolutionary and Environmental Biology, Faculty of Natural Science, University of Haifa, Haifa 3498838, Israel
Solomon Wasser, Institute of Evolution and Department of Evolutionary and Environmental Biology, Faculty of Natural Science, University of Haifa, Haifa 3498838, Israel
Eviatar Nevo, Institute of Evolution, Faculty of Natural Science, University of Haifa, Haifa 3498838, Israel
Natalia Sybirna, Department of Biochemistry, Faculty of Biology, Ivan Franko National University of Lviv, Lviv 79005, Ukraine
Author contributions: Vitak T and Yurkiv B wrote the manuscript; Wasser S, Nevo E and Sybirna N reviewed and edited the manuscript.
Conflict-of-interest statement: Authors declare no conflict of interests for this article.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Taras Vitak, PhD, Department of Evolutionary and Environmental Biology, Faculty of Natural Science, University of Haifa, Abba Khoushy Ave 199, Haifa 3498838, Israel. taras.vitak90@gmail.com
Telephone: +38-096-8327983
Received: October 28, 2016
Peer-review started: October 31, 2016
First decision: January 14, 2017
Revised: February 13, 2017
Accepted: March 12, 2017
Article in press: March 13, 2017
Published online: May 15, 2017
Core Tip

Core tip: Diabetes mellitus (DM) is the third most common non-infectious disease leading to early disability and high mortality. The main symptom of DM is hyperglycemia. Metabolic disorders caused by insulin deficiency in diabetes significantly impede the functioning of a homeostasis system. Medicinal mushrooms play an important role among new preparations that aim to decrease blood glucose levels. This investigations show pronounced hypoglycemic, anti-anemic, membrane protective, apoptosis suppressive effects of Agaricus brasiliensis and Ganoderma lucidum on streptozotocin-induced DM in rats. Thus, medicinal mushrooms might be new effective approach for treatment and prevention of DM.