Published online Feb 15, 2015. doi: 10.4239/wjd.v6.i1.151
Peer-review started: August 29, 2014
First decision: September 30, 2014
Revised: October 9, 2014
Accepted: December 16, 2014
Article in press: December 17, 2014
Published online: February 15, 2015
Core tip: Diabetes mellitus and related metabolic disorders like obesity, dyslipidemia are emerging as major global health challenges in recent era. Adiponectin, an adipokine demands profound importance in the field of metabolomics due to its potential role in all these complications. Plasma adiponectin concentration is remarkably lower in subjects with metabolic disorders predicting its significant role as an important biomarker in disease prognosis. We have attempted to enlighten adiponectin function stretching its role as a modulator associating these metabolic obstacles. We believe, this article will surely contribute to the fundamental and clinical research in the field of diabetes and related complications.