BPG is committed to discovery and dissemination of knowledge
Open-Access Journal
Editorial
Body mass index and colon cancer screening: The road ahead 
Kanwarpreet Tandon, Mohamad Imam, Bahaa Eldeen Senousy Ismail, Fernando Castro 
World J Gastroenterol 21(5):1371-1376. Published online Feb 7, 2015. doi: 10.3748/wjg.v21.i5.1371
Review
Role of dietary phospholipids and phytosterols in protection against peptic ulceration as shown by experiments on rats 
Frank I Tovey 
World J Gastroenterol 21(5):1377-1384. Published online Feb 7, 2015. doi: 10.3748/wjg.v21.i5.1377
Deep enteroscopy - indications, diagnostic yield and complications 
Oliver Moeschler, Michael Karl Mueller 
World J Gastroenterol 21(5):1385-1393. Published online Feb 7, 2015. doi: 10.3748/wjg.v21.i5.1385
Management of perianal fistulas in Crohn’s disease: An up-to-date review 
Manuela Marzo, Carla Felice, Daniela Pugliese, Gianluca Andrisani, Giammarco Mocci, Alessandro Armuzzi, Luisa Guidi 
World J Gastroenterol 21(5):1394-1403. Published online Feb 7, 2015. doi: 10.3748/wjg.v21.i5.1394
Jaundice associated pruritis: A review of pathophysiology and treatment 
Ramez Bassari, Jonathan B Koea 
World J Gastroenterol 21(5):1404-1413. Published online Feb 7, 2015. doi: 10.3748/wjg.v21.i5.1404
Association between Helicobacter spp. infections and hepatobiliary malignancies: A review 
Fany Karina Segura-López, Alfredo Güitrón-Cantú, Javier Torres 
World J Gastroenterol 21(5):1414-1423. Published online Feb 7, 2015. doi: 10.3748/wjg.v21.i5.1414
High-mobility group box 1 protein and its role in severe acute pancreatitis 
Xiao Shen, Wei-Qin Li 
World J Gastroenterol 21(5):1424-1435. Published online Feb 7, 2015. doi: 10.3748/wjg.v21.i5.1424
Minireviews
Extending the functions of the homeotic transcription factor Cdx2 in the digestive system through nontranscriptional activities 
Jean-Noël Freund, Isabelle Duluc, Jean-Marie Reimund, Isabelle Gross, Claire Domon-Dell 
World J Gastroenterol 21(5):1436-1443. Published online Feb 7, 2015. doi: 10.3748/wjg.v21.i5.1436
Basic Study
Mechanism involved in Danshen-induced fluid secretion in salivary glands 
Fei Wei, Mu-Xin Wei, Masataka Murakami 
World J Gastroenterol 21(5):1444-1456. Published online Feb 7, 2015. doi: 10.3748/wjg.v21.i5.1444
Loss of CDX2 expression is associated with poor prognosis in colorectal cancer patients 
Jeong Mo Bae, Tae Hun Lee, Nam-Yun Cho, Tae-You Kim, Gyeong Hoon Kang 
World J Gastroenterol 21(5):1457-1467. Published online Feb 7, 2015. doi: 10.3748/wjg.v21.i5.1457
Electroacupuncture activates enteric glial cells and protects the gut barrier in hemorrhaged rats 
Sen Hu, Zeng-Kai Zhao, Rui Liu, Hai-Bin Wang, Chun-Yu Gu, Hong-Min Luo, Huan Wang, Ming-Hua Du, Yi Lv, Xian Shi 
World J Gastroenterol 21(5):1468-1478. Published online Feb 7, 2015. doi: 10.3748/wjg.v21.i5.1468
Xiaotan Sanjie decoction inhibits interleukin-8-induced metastatic potency in gastric cancer 
Jun Shi, Pin-Kang Wei 
World J Gastroenterol 21(5):1479-1487. Published online Feb 7, 2015. doi: 10.3748/wjg.v21.i5.1479
MiR-21/RASA1 axis affects malignancy of colon cancer cells via RAS pathways 
Bo Gong, Wan-Wei Liu, Wen-Jing Nie, Dong-Feng Li, Zi-Jun Xie, Chao Liu, Yan-Hui Liu, Ping Mei, Zi-Jun Li 
World J Gastroenterol 21(5):1488-1497. Published online Feb 7, 2015. doi: 10.3748/wjg.v21.i5.1488
S-phase arrest after vincristine treatment may promote hepatitis B virus replication 
Lei Xu, Zeng Tu, Ge Xu, Jie-Li Hu, Xue-Fei Cai, Xing-Xing Zhan, Yu-Wei Wang, Yuan Huang, Juan Chen, Ai-Long Huang 
World J Gastroenterol 21(5):1498-1509. Published online Feb 7, 2015. doi: 10.3748/wjg.v21.i5.1498
Crude extract of maggots: Antibacterial effects against Escherichia coli, underlying mechanisms, separation and purification 
Quan-Sheng Ge, Hui-Min Zhang, Xia Liu, Shou-Yu Wang, De-Cheng Lv, Xu-Dong Li 
World J Gastroenterol 21(5):1510-1517. Published online Feb 7, 2015. doi: 10.3748/wjg.v21.i5.1510
CNP signal pathway up-regulated in rectum of depressed rats and the interventional effect of Xiaoyaosan 
Ping Li, Xu-Dong Tang, Zheng-Xu Cai, Juan-Juan Qiu, Xue-Lian Lin, Tong Zhu, Lawrence Owusu, Hui-Shu Guo 
World J Gastroenterol 21(5):1518-1530. Published online Feb 7, 2015. doi: 10.3748/wjg.v21.i5.1518
Interleukin-22 ameliorates liver fibrogenesis by attenuating hepatic stellate cell activation and downregulating the levels of inflammatory cytokines 
Dong-Hong Lu, Xiao-Yun Guo, Shan-Yu Qin, Wei Luo, Xiao-Li Huang, Mei Chen, Jia-Xu Wang, Shi-Jia Ma, Xian-Wen Yang, Hai-Xing Jiang 
World J Gastroenterol 21(5):1531-1545. Published online Feb 7, 2015. doi: 10.3748/wjg.v21.i5.1531
Case Control Study
Passive-bending, short-type single-balloon enteroscope for endoscopic retrograde cholangiopancreatography in Roux-en-Y anastomosis patients 
Hiroshi Yamauchi, Mitsuhiro Kida, Kosuke Okuwaki, Shiro Miyazawa, Tomohisa Iwai, Shuko Tokunaga, Miyoko Takezawa, Hiroshi Imaizumi, Wasaburo Koizumi 
World J Gastroenterol 21(5):1546-1553. Published online Feb 7, 2015. doi: 10.3748/wjg.v21.i5.1546
Retrospective Cohort Study
Radiofrequency ablation of hepatocellular carcinoma in difficult locations: Strategies and long-term outcomes 
Wei Yang, Kun Yan, Gong-Xiong Wu, Wei Wu, Ying Fu, Jung-Chieh Lee, Zhong-Yi Zhang, Song Wang, Min-Hua Chen 
World J Gastroenterol 21(5):1554-1566. Published online Feb 7, 2015. doi: 10.3748/wjg.v21.i5.1554
Retrospective Study
Intragastric band erosion: Experiences with gastrointestinal endoscopic removal 
Edo Oscar Aarts, Bas van Wageningen, Frits Berends, Ignace Janssen, Peter Wahab, Marcel Groenen 
World J Gastroenterol 21(5):1567-1572. Published online Feb 7, 2015. doi: 10.3748/wjg.v21.i5.1567
Computed tomography attenuation values of ascites are helpful to predict perforation site 
Ryo Seishima, Koji Okabayashi, Hirotoshi Hasegawa, Masashi Tsuruta, Hiroki Hoshino, Toru Yamada, Yuko Kitagawa 
World J Gastroenterol 21(5):1573-1579. Published online Feb 7, 2015. doi: 10.3748/wjg.v21.i5.1573
Comparison between uncovered and covered self-expandable metal stent placement in malignant duodenal obstruction 
Ji Won Kim, Ji Bong Jeong, Kook Lae Lee, Byeong Gwan Kim, Dong Won Ahn, Jae Kyung Lee, Su Hwan Kim 
World J Gastroenterol 21(5):1580-1587. Published online Feb 7, 2015. doi: 10.3748/wjg.v21.i5.1580
Laparoscopic pancreaticoduodenectomy via a reverse-''V'' approach with four ports: Initial experience and perioperative outcomes 
Zhao Liu, Mu-Chuan Yu, Rui Zhao, Yan-Feng Liu, Jian-Ping Zeng, Xian-Qiang Wang, Jing-Wang Tan 
World J Gastroenterol 21(5):1588-1594. Published online Feb 7, 2015. doi: 10.3748/wjg.v21.i5.1588
KRAS and BRAF gene mutations and DNA mismatch repair status in Chinese colorectal carcinoma patients 
Ju-Xiang Ye, Yan Liu, Yun Qin, Hao-Hao Zhong, Wei-Ning Yi, Xue-Ying Shi 
World J Gastroenterol 21(5):1595-1605. Published online Feb 7, 2015. doi: 10.3748/wjg.v21.i5.1595
Learning curve for hand-assisted laparoscopic D2 radical gastrectomy 
Jia-Qing Gong, Yong-Kuan Cao, Yong-Hua Wang, Guo-Hu Zhang, Pei-Hong Wang, Guo-De Luo 
World J Gastroenterol 21(5):1606-1613. Published online Feb 7, 2015. doi: 10.3748/wjg.v21.i5.1606
Observational Study
High prevalence of vitamin A deficiency in Crohn's disease patients according to serum retinol levels and the relative dose-response test 
Márcia Soares-Mota, Tianny A Silva, Luanda M Gomes, Marco AS Pinto, Laura MC Mendonça, Maria Lúcia F Farias, Tiago Nunes, Andrea Ramalho, Cyrla Zaltman 
World J Gastroenterol 21(5):1614-1620. Published online Feb 7, 2015. doi: 10.3748/wjg.v21.i5.1614
Meta-Analysis
Lesion discrimination with breath-hold hepatic diffusion-weighted imaging: A meta-analysis 
Zhi-Guang Chen, Li Xu, Si-Wei Zhang, Yan Huang, Rui-Huan Pan 
World J Gastroenterol 21(5):1621-1627. Published online Feb 7, 2015. doi: 10.3748/wjg.v21.i5.1621
Impact of lymph node micrometastasis on gastric carcinoma prognosis: A meta-analysis 
Yong-Ji Zeng, Chun-Dong Zhang, Dong-Qiu Dai 
World J Gastroenterol 21(5):1628-1635. Published online Feb 7, 2015. doi: 10.3748/wjg.v21.i5.1628
Peri-operative use of sorafenib in liver transplantation: A time-to-event meta-analysis 
Hao-Long Qi, Bing-Jie Zhuang, Chang-Sheng Li, Quan-Yan Liu 
World J Gastroenterol 21(5):1636-1640. Published online Feb 7, 2015. doi: 10.3748/wjg.v21.i5.1636
HIF-1α -1790G>A polymorphism significantly increases the risk of digestive tract cancer: A meta-analysis 
Xiao Sun, Ying-Di Liu, Wei Gao, Shao-Hua Shen, Meng Li 
World J Gastroenterol 21(5):1641-1649. Published online Feb 7, 2015. doi: 10.3748/wjg.v21.i5.1641
Central obesity and nonalcoholic fatty liver disease risk after adjusting for body mass index 
Qing Pang, Jing-Yao Zhang, Si-Dong Song, Kai Qu, Xin-Sen Xu, Su-Shun Liu, Chang Liu 
World J Gastroenterol 21(5):1650-1662. Published online Feb 7, 2015. doi: 10.3748/wjg.v21.i5.1650
Case Report
High-grade dysplasia, restricted to the basal cell layer involving the entire esophagus 
Mario Sarbia, Stefan Wolfer, Diana Karimi, Albert Eimiller 
World J Gastroenterol 21(5):1663-1665. Published online Feb 7, 2015. doi: 10.3748/wjg.v21.i5.1663
Successful treatment of life-threatening bleeding from a duodenal posterior bulb peptic ulcer by an over-the-scope-clip 
Thorsten Brechmann, Wolff Schmiegel 
World J Gastroenterol 21(5):1666-1669. Published online Feb 7, 2015. doi: 10.3748/wjg.v21.i5.1666
Gastrojejunostomy for pyloric stenosis after acute gastric dilatation due to overeating 
Akiharu Kimura, Norihiro Masuda, Norihiro Haga, Tomokazu Ito, Kichirou Otsuka, Jyunko Takita, Hitoshi Satomura, Yuji Kumakura, Hiroyuki Kato, Hiroyuki Kuwano 
World J Gastroenterol 21(5):1670-1674. Published online Feb 7, 2015. doi: 10.3748/wjg.v21.i5.1670
Castleman’s disease of the spleen 
Hee-Jeong Lee, Ho-Jong Jeon, Sang-Gon Park, Chi-Young Park 
World J Gastroenterol 21(5):1675-1679. Published online Feb 7, 2015. doi: 10.3748/wjg.v21.i5.1675
Belching, regurgitation, chest tightness and dyspnea: Not gastroesophageal reflux disease but asthma 
Jing-Xi Zhang, Xian-Bao Zhan, Chong Bai, Qiang Li 
World J Gastroenterol 21(5):1680-1683. Published online Feb 7, 2015. doi: 10.3748/wjg.v21.i5.1680
Gastric metastasis from small cell lung cancer: A case report 
Song Gao, Xu-Dong Hu, Su-Zhen Wang, Ning Liu, Wei Zhao, Qing-Xi Yu, Wen-Hong Hou, Shuang-Hu Yuan 
World J Gastroenterol 21(5):1684-1688. Published online Feb 7, 2015. doi: 10.3748/wjg.v21.i5.1684
Letters To The Editor
Unfavorable outcome of antiviral therapy in cytomegalovirus-positive ulcerative colitis may be due to inappropriate study inclusion in meta-analysis 
Xiao-Wei Wu, Miao-Fang Yang, Nan Li, Fang-Yu Wang 
World J Gastroenterol 21(5):1689-1690. Published online Feb 7, 2015. doi: 10.3748/wjg.v21.i5.1689