Meta-Analysis
Copyright ©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Feb 7, 2015; 21(5): 1636-1640
Published online Feb 7, 2015. doi: 10.3748/wjg.v21.i5.1636
Peri-operative use of sorafenib in liver transplantation: A time-to-event meta-analysis
Hao-Long Qi, Bing-Jie Zhuang, Chang-Sheng Li, Quan-Yan Liu
Hao-Long Qi, Bing-Jie Zhuang, Chang-Sheng Li, Quan-Yan Liu, Department of General Surgery, Research Center of Digestive Diseases, Zhongnan Hospital, Wuhan University, Wuhan 430071, Hubei Province, China
Author contributions: Qi HL and Zhuang BJ performed the information retrieval, screened the potential subjects, and extracted and integrated the data independently at the same time; Li CS and Liu QY designed the study and wrote the manuscript.
Supported by National Natural Science Foundation of China, No. 81172349 and No. 30872491.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Quan-Yan Liu, Professor, Department of General Surgery, Research Center of Digestive Diseases, Zhongnan Hospital, Wuhan University, No. 299 Ba Yi Road, Wuhan 430071, Hubei Province, China. 1459195529@qq.com
Telephone: +86-27-67812588 Fax: +86-27-87336735
Received: June 27, 2014
Peer-review started: June 28, 2014
First decision: July 21, 2014
Revised: August 9, 2014
Accepted: September 19, 2014
Article in press: September 19, 2014
Published online: February 7, 2015
Core Tip

Core tip: The data were extracted from the Kaplan-Meier curves of every study identified and then input into a hazard ratio calculation spreadsheet. The HRs generated from the sheet were combined with RevMan5.0. To the best of our knowledge, this is the first meta-analysis assessing the use of sorafenib in the peri-operative period of liver transplantation.