Meta-Analysis
Copyright ©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Feb 7, 2015; 21(5): 1621-1627
Published online Feb 7, 2015. doi: 10.3748/wjg.v21.i5.1621
Lesion discrimination with breath-hold hepatic diffusion-weighted imaging: A meta-analysis
Zhi-Guang Chen, Li Xu, Si-Wei Zhang, Yan Huang, Rui-Huan Pan
Zhi-Guang Chen, Li Xu, Si-Wei Zhang, Department of Radiology, Guangdong Provincial Traditional Chinese Medicine Hospital, Guangzhou 510120, Guangdong Province, China
Yan Huang, Rui-Huan Pan, Department of Neurology, Guangdong Provincial Traditional Chinese Medicine Hospital, Guangzhou 510120, Guangdong Province, China
Author contributions: Chen ZG and Xu L designed the study, analyzed the data and wrote the manuscript; Xu L and Pan RH contributed to the discussion; Xu L, Zhang SW and Huang Y revised the manuscript.
Supported by Grants from the Science Foundation of Guangdong Province for Doctorate Startup Project, No. S2012040006618; and the Postdoctoral Fund of Guangzhou University of Traditional Chinese Medicine, No. 20120621.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Li Xu, MD, Department of Radiology, Guangdong Provincial Traditional Chinese Medicine Hospital, No. 111 Da De Road, Guangzhou 510120, Guangdong Province, China. 985592610@qq.com
Telephone: +86-20-81887233 Fax: +86-20-81887233
Received: June 26, 2014
Peer-review started: June 27, 2014
First decision: July 21, 2014
Revised: August 23, 2014
Accepted: September 30, 2014
Article in press: September 30, 2014
Published online: February 7, 2015
Core Tip

Core tip: We investigated the diagnostic capability of breath-hold diffusion-weighted imaging (DWI) and found that it is useful for differentiating between malignant and benign hepatic focal lesions. The diffusion characteristics of the benign liver lesions that mimic malignant lesions have rarely been investigated and further studies are needed. Standardization of the acquisition protocol for breath-hold DWI across multicenter trials is recommended.