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Topic Highlight
Hepatitis C virus core antigen testing: Role in diagnosis, disease monitoring and treatment 
Hans L Tillmann 
World J Gastroenterol 20(22):6701-6706. Published online Jun 14, 2014. doi: 10.3748/wjg.v20.i22.6701
Hepatic flares in chronic hepatitis C: Spontaneous exacerbation vs hepatotropic viruses superinfection 
Evangelista Sagnelli, Caterina Sagnelli, Mariantonietta Pisaturo, Nicola Coppola 
World J Gastroenterol 20(22):6707-6715. Published online Jun 14, 2014. doi: 10.3748/wjg.v20.i22.6707
Hepatitis C virus reactivation in cancer patients in the era of targeted therapies 
Ozan Yazici, Mehmet Ali Nahit Şendur, Sercan Aksoy 
World J Gastroenterol 20(22):6716-6724. Published online Jun 14, 2014. doi: 10.3748/wjg.v20.i22.6716
Gender-related differences in irritable bowel syndrome: Potential mechanisms of sex hormones 
Mathieu Meleine, Julien Matricon 
World J Gastroenterol 20(22):6725-6743. Published online Jun 14, 2014. doi: 10.3748/wjg.v20.i22.6725
Cognitive behavioral approach to understanding irritable bowel syndrome 
Goran Hauser, Sanda Pletikosic, Mladenka Tkalcic 
World J Gastroenterol 20(22):6744-6758. Published online Jun 14, 2014. doi: 10.3748/wjg.v20.i22.6744
Irritable bowel syndrome: Pathogenesis, diagnosis, treatment, and evidence-based medicine 
Lekha Saha 
World J Gastroenterol 20(22):6759-6773. Published online Jun 14, 2014. doi: 10.3748/wjg.v20.i22.6759
Inflammatory colonic carcinogenesis: A review on pathogenesis and immunosurveillance mechanisms in ulcerative colitis 
Marco Scarpa, Ignazio Castagliuolo, Carlo Castoro, Anna Pozza, Melania Scarpa, Andromachi Kotsafti, Imerio Angriman 
World J Gastroenterol 20(22):6774-6785. Published online Jun 14, 2014. doi: 10.3748/wjg.v20.i22.6774
Colorectal cancer: From prevention to personalized medicine 
Gemma Binefa, Francisco Rodríguez-Moranta, Àlex Teule, Manuel Medina-Hayas 
World J Gastroenterol 20(22):6786-6808. Published online Jun 14, 2014. doi: 10.3748/wjg.v20.i22.6786
Prognostic and predictive significance of MSI in stages II/III colon cancer 
Zacharenia Saridaki, John Souglakos, Vassilis Georgoulias 
World J Gastroenterol 20(22):6809-6814. Published online Jun 14, 2014. doi: 10.3748/wjg.v20.i22.6809
Synchronous colorectal cancer: Clinical, pathological and molecular implications 
Alfred King-Yin Lam, Sally Sze-Yan Chan, Melissa Leung 
World J Gastroenterol 20(22):6815-6820. Published online Jun 14, 2014. doi: 10.3748/wjg.v20.i22.6815
Review
Bedside ultrasound in the diagnosis of nonalcoholic fatty liver disease 
Nancy Khov, Amol Sharma, Thomas R Riley 
World J Gastroenterol 20(22):6821-6825. Published online Jun 14, 2014. doi: 10.3748/wjg.v20.i22.6821
Minireviews
Input of microenvironmental regulation on colorectal cancer: Role of the CCN family 
Cheng-Chi Chang, Been-Ren Lin, Tai-Sheng Wu, Yung-Ming Jeng, Min-Liang Kuo 
World J Gastroenterol 20(22):6826-6831. Published online Jun 14, 2014. doi: 10.3748/wjg.v20.i22.6826
Original Article
Multispecies probiotic protects gut barrier function in experimental models 
Mylene Nébot-Vivinus, Cherryl Harkat, Hanene Bzioueche, Christel Cartier, Raffaella Plichon-Dainese, Lara Moussa, Helene Eutamene, Dorsa Pishvaie, Sophie Holowacz, Christian Seyrig, Thierry Piche, Vassilia Theodorou 
World J Gastroenterol 20(22):6832-6843. Published online Jun 14, 2014. doi: 10.3748/wjg.v20.i22.6832
Role of the Na+/K+/2Cl- cotransporter NKCC1 in cell cycle progression in human esophageal squamous cell carcinoma 
Atsushi Shiozaki, Yoshito Nako, Daisuke Ichikawa, Hirotaka Konishi, Shuhei Komatsu, Takeshi Kubota, Hitoshi Fujiwara, Kazuma Okamoto, Mitsuo Kishimoto, Yoshinori Marunaka, Eigo Otsuji 
World J Gastroenterol 20(22):6844-6859. Published online Jun 14, 2014. doi: 10.3748/wjg.v20.i22.6844
Research Report
Carcinogenic Helicobacter pylori in gastric pre-cancer and cancer lesions: Association with tobacco-chewing 
Arvind Pandey, Satyendra Chandra Tripathi, Sutapa Mahata, Kanchan Vishnoi, Shirish Shukla, Sri Prakash Misra, Vatsala Misra, Suresh Hedau, Ravi Mehrotra, Manisha Dwivedi, Alok C Bharti 
World J Gastroenterol 20(22):6860-6868. Published online Jun 14, 2014. doi: 10.3748/wjg.v20.i22.6860
Evaluation of a novel choanoid fluidized bed bioreactor for future bioartificial livers 
Cheng-Bo Yu, Xiao-Ping Pan, Liang Yu, Xiao-Peng Yu, Wei-Bo Du, Hong-Cui Cao, Jun Li, Ping Chen, Lan-Juan Li 
World J Gastroenterol 20(22):6869-6877. Published online Jun 14, 2014. doi: 10.3748/wjg.v20.i22.6869
Laparoendoscopic single-site distal pancreatectomy in pigs 
Dong Wang, Zhen-Ling Ji, Xiao-Hua Jiang, Jing-Min Wang, Yu-Yan Tan, Yan Wang, Ya-Zhou Wen 
World J Gastroenterol 20(22):6878-6883. Published online Jun 14, 2014. doi: 10.3748/wjg.v20.i22.6878
Mesothelin promotes cell proliferation in the remodeling of neonatal rat pancreas 
Dan-Dan Yin, Liang-Hui You, Qing-Xin Yuan, Xiao-Di Liang, Ning Wang, Lin-Tao Wang, Li Yuan, Ke-Ming Wang, Wei De 
World J Gastroenterol 20(22):6884-6896. Published online Jun 14, 2014. doi: 10.3748/wjg.v20.i22.6884
Expression of gastrointestinal nesfatin-1 and gastric emptying in ventromedial hypothalamic nucleus- and ventrolateral hypothalamic nucleus-lesioned rats 
Zi-Bin Tian, Run-Jun Deng, Gui-Rong Sun, Liang-Zhou Wei, Xin-Juan Kong, Xue-Li Ding, Xue Jing, Cui-Ping Zhang, Yin-Lin Ge 
World J Gastroenterol 20(22):6897-6905. Published online Jun 14, 2014. doi: 10.3748/wjg.v20.i22.6897
Reduced expression of circulating microRNA-218 in gastric cancer and correlation with tumor invasion and prognosis 
Shi-Yong Xin, Xiao-Shan Feng, Li-Qing Zhou, Jun-Jun Sun, Xiao-Le Gao, Guo-Liang Yao 
World J Gastroenterol 20(22):6906-6911. Published online Jun 14, 2014. doi: 10.3748/wjg.v20.i22.6906
Evidence-Based Medicine
Serum adipokines in inflammatory bowel disease 
Marek Waluga, Marek Hartleb, Grzegorz Boryczka, Michał Kukla, Krystyna Żwirska-Korczala 
World J Gastroenterol 20(22):6912-6917. Published online Jun 14, 2014. doi: 10.3748/wjg.v20.i22.6912
Helicobacter pylori eradication in patients with chronic immune thrombocytopenic purpura 
Ravinder Naik Noonavath, Chandrasekharan Padma Lakshmi, Tarun Kumar Dutta, Vikram Kate 
World J Gastroenterol 20(22):6918-6923. Published online Jun 14, 2014. doi: 10.3748/wjg.v20.i22.6918
Non-surgical treatment of post-surgical bile duct injury: Clinical implications and outcomes 
Young Ook Eum, Joo Kyung Park, Jaeyoung Chun, Sang-Hyub Lee, Ji Kon Ryu, Yong-Tae Kim, Yong-Bum Yoon, Chang Jin Yoon, Ho-Seong Han, Jin-Hyeok Hwang 
World J Gastroenterol 20(22):6924-6931. Published online Jun 14, 2014. doi: 10.3748/wjg.v20.i22.6924
Helicobacter pylori eradication with moxifloxacin-containing therapy following failed first-line therapies in South Korea 
Kyu Keun Kang, Dong Ho Lee, Dong Hyun Oh, Hyuk Yoon, Cheol Min Shin, Young Soo Park, Nayoung Kim, Hyun Chae Jung 
World J Gastroenterol 20(22):6932-6938. Published online Jun 14, 2014. doi: 10.3748/wjg.v20.i22.6932
Case Control Study
Solid pseudopapillary tumor of the pancreas in male patients: Report of 16 cases 
Yun-Qiang Cai, Si-Ming Xie, Xun Ran, Xing Wang, Gang Mai, Xu-Bao Liu 
World J Gastroenterol 20(22):6939-6945. Published online Jun 14, 2014. doi: 10.3748/wjg.v20.i22.6939
Retrospective Study
Diabetes mellitus increases risk for colorectal adenomas in younger patients 
Hongha T Vu, Nneka Ufere, Yan Yan, Jean S Wang, Dayna S Early, Jill E Elwing 
World J Gastroenterol 20(22):6946-6952. Published online Jun 14, 2014. doi: 10.3748/wjg.v20.i22.6946
Liver regeneration after liver resection: Clinical aspects and correlation with infective complications 
Duilio Pagano, Marco Spada, Vishal Parikh, Fabio Tuzzolino, Davide Cintorino, Luigi Maruzzelli, Giovanni Vizzini, Angelo Luca, Alessandra Mularoni, Paolo Grossi, Bruno Gridelli, Salvatore Gruttadauria 
World J Gastroenterol 20(22):6953-6960. Published online Jun 14, 2014. doi: 10.3748/wjg.v20.i22.6953
Factors associated with incomplete colonoscopy at a Japanese academic hospital 
Shigeo Koido, Toshifumi Ohkusa, Kosaburo Nakae, Tetsuji Yokoyama, Tomoyoshi Shibuya, Naoto Sakamoto, Kan Uchiyama, Hiroshi Arakawa, Taro Osada, Akihito Nagahara, Sumio Watanabe, Hisao Tajiri 
World J Gastroenterol 20(22):6961-6967. Published online Jun 14, 2014. doi: 10.3748/wjg.v20.i22.6961
Evaluation of endoscopic biliary stenting for obstructive jaundice caused by hepatocellular carcinoma 
Gen Sugiyama, Yoshinobu Okabe, Yusuke Ishida, Fumihiko Saitou, Ryuichi Kawahara, Hiroto Ishikawa, Hiroyuki Horiuchi, Hisafumi Kinoshita, Osamu Tsuruta, Michio Sata 
World J Gastroenterol 20(22):6968-6973. Published online Jun 14, 2014. doi: 10.3748/wjg.v20.i22.6968
Influence of adriamycin on changes in Nanog, Oct-4, Sox2, ARID1 and Wnt5b expression in liver cancer stem cells 
Ding Sun, Lei Qin, Yang Xu, Jian-Xia Liu, Li-Ping Tian, Hai-Xin Qian 
World J Gastroenterol 20(22):6974-6980. Published online Jun 14, 2014. doi: 10.3748/wjg.v20.i22.6974
Clinical Trials Study
Should peri-gastrectomy gastric acidity be our focus among gastric cancer patients? 
Lei Huang, A-Man Xu, Tuan-Jie Li, Wen-Xiu Han, Jing Xu 
World J Gastroenterol 20(22):6981-6988. Published online Jun 14, 2014. doi: 10.3748/wjg.v20.i22.6981
New index to predict esophageal variceal bleeding in cirrhotic patients 
Xiao-Dan Xu, Jian-Jun Dai, Jian-Qing Qian, Xun Pin, Wei-Jun Wang 
World J Gastroenterol 20(22):6989-6994. Published online Jun 14, 2014. doi: 10.3748/wjg.v20.i22.6989
Observational Study
Risk factors and therapeutic results of early local recurrence after transcatheter arterial chemoembolization 
Woo Sun Rou, Byung Seok Lee, Hee Seok Moon, Eaum Seok Lee, Seok Hyun Kim, Heon Young Lee 
World J Gastroenterol 20(22):6995-7004. Published online Jun 14, 2014. doi: 10.3748/wjg.v20.i22.6995
Magnetic resonance cholangiopancreatography study of pancreaticobiliary maljunction and pancreaticobiliary diseases 
Cheng-Lin Wang, He-Yu Ding, Yi Dai, Ting-Ting Xie, Yong-Bin Li, Lin Cheng, Bing Wang, Run-Hui Tang, Wei-Xia Nie 
World J Gastroenterol 20(22):7005-7010. Published online Jun 14, 2014. doi: 10.3748/wjg.v20.i22.7005
Prospective Study
Subclinical abnormal glucose tolerance is a predictor of death in liver cirrhosis 
Diego García-Compeán, Joel Omar Jáquez-Quintana, Fernando Javier Lavalle-González, José Alberto González-González, Linda Elsa Muñoz-Espinosa, Jesús Zacarías Villarreal-Pérez, Héctor J Maldonado-Garza 
World J Gastroenterol 20(22):7011-7018. Published online Jun 14, 2014. doi: 10.3748/wjg.v20.i22.7011
Correlations between skin lesions induced by anti-tumor necrosis factor-α and selected cytokines in Crohn's disease patients 
Marcin Włodarczyk, Aleksandra Sobolewska, Bartosz Wójcik, Karolina Loga, Jakub Fichna, Maria Wiśniewska-Jarosińska 
World J Gastroenterol 20(22):7019-7026. Published online Jun 14, 2014. doi: 10.3748/wjg.v20.i22.7019
Impairment of gastrointestinal quality of life in severely obese patients 
Po-Jui Yu, Ju-Juin Tsou, Wei-Jei Lee, Kuo-Ting Lee, Yi-Chih Lee 
World J Gastroenterol 20(22):7027-7033. Published online Jun 14, 2014. doi: 10.3748/wjg.v20.i22.7027
Meta-Analysis
Does hyoscine butylbromide really improve polyp detection during colonoscopy? A meta-analysis of randomized controlled trials 
Pei-Jing Cui, Jing Yao, Hua-Zhong Han, Yi-Jun Zhao, Jun Yang 
World J Gastroenterol 20(22):7034-7039. Published online Jun 14, 2014. doi: 10.3748/wjg.v20.i22.7034
Placement of prophylactic pancreatic stents to prevent post-endoscopic retrograde cholangiopancreatography pancreatitis in high-risk patients: A meta-analysis 
Qing-Qing Shi, Xiao-Yi Ning, Ling-Ling Zhan, Guo-Du Tang, Xiao-Ping Lv 
World J Gastroenterol 20(22):7040-7048. Published online Jun 14, 2014. doi: 10.3748/wjg.v20.i22.7040
Case Report
Long-term durable response to lenalidomide in a patient with hepatic epithelioid hemangioendothelioma 
Maria Caterina Pallotti, Margherita Nannini, Claudio Agostinelli, Simona Leoni, Valerio Di Scioscio, Anna Mandrioli, Cristian Lolli, Maristella Saponara, Stefano Pileri, Luigi Bolondi, Guido Biasco, Maria Abbondanza Pantaleo 
World J Gastroenterol 20(22):7049-7054. Published online Jun 14, 2014. doi: 10.3748/wjg.v20.i22.7049
Primary esophageal sclerosing mucoepidermoid carcinoma with “tissue eosinophilia” 
Suman Mewa Kinoo, Kapil Maharaj, Bhugwan Singh, Michelle Govender, Pratistadevi Kanaye Ramdial 
World J Gastroenterol 20(22):7055-7060. Published online Jun 14, 2014. doi: 10.3748/wjg.v20.i22.7055
Diagnosis and management of choledochal cyst: 20 years of single center experience 
Nabil Gadelhak, Ahmed Shehta, Hosam Hamed 
World J Gastroenterol 20(22):7061-7066. Published online Jun 14, 2014. doi: 10.3748/wjg.v20.i22.7061
Expression of alpha smooth muscle actin in living donor liver transplant recipients 
Masataka Hirabaru, Kyoko Mochizuki, Mitsuhisa Takatsuki, Akihiko Soyama, Taiichiro Kosaka, Tamotsu Kuroki, Isao Shimokawa, Susumu Eguchi 
World J Gastroenterol 20(22):7067-7074. Published online Jun 14, 2014. doi: 10.3748/wjg.v20.i22.7067
Fish bone migration to the urinary bladder after rectosigmoid colon perforation 
Min-Kyung Cho, Moon-Soo Lee, Hyun-Young Han, Seung Hyo Woo 
World J Gastroenterol 20(22):7075-7078. Published online Jun 14, 2014. doi: 10.3748/wjg.v20.i22.7075