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World J Gastroenterol. Jun 14, 2014; 20(22): 6953-6960
Published online Jun 14, 2014. doi: 10.3748/wjg.v20.i22.6953
Published online Jun 14, 2014. doi: 10.3748/wjg.v20.i22.6953
Liver regeneration after liver resection: Clinical aspects and correlation with infective complications
Duilio Pagano, Marco Spada, Fabio Tuzzolino, Davide Cintorino, Luigi Maruzzelli, Giovanni Vizzini, Angelo Luca, Alessandra Mularoni, Paolo Grossi, Bruno Gridelli, Salvatore Gruttadauria, Istituto Mediterraneo Trapianti e Terapie ad Alta Specializzazione, University of Pittsburgh Medical Center in Italy, 90127 Palermo, Italy
Marco Spada, Davide Cintorino, Bruno Gridelli, Salvatore Gruttadauria, Department of Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, United States
Paolo Grossi, Infectious Diseases Section, Department of Surgical and Morphological Sciences, University of Insubria, 21100 Varese, Italy
Vishal Parikh, School of Medicine, University of Pittsburgh Medical Center, Pittsburgh, PA 15261, United States
Author contributions: Gruttadauria S drafted the article critically for important intellectual content; Pagano D, Spada M, Tuzzolino F, Cintorino D, Maruzzelli L, Vizzini G, Luca A, Mularoni A, Grossi P, Gridelli B and Parikh V gave substantial contributions to concept and design, acquisition of data, and interpretation of data; Gruttadauria S, Spada M and Gridelli B gave the final approval of the version to be published.
Correspondence to: Salvatore Gruttadauria, MD, Associate Professor of Surgery, Istituto Mediterraneo Trapianti e Terapie ad Alta Specializzazione, University of Pittsburgh Medical Center in Italy, Via E. Tricomi, 1, 90127 Palermo, Italy. sgruttadauria@ismett.edu
Telephone: +39-91-2192111 Fax: +39-91-2192400
Received: November 5, 2013
Revised: February 13, 2014
Accepted: March 12, 2014
Published online: June 14, 2014
Revised: February 13, 2014
Accepted: March 12, 2014
Published online: June 14, 2014
Core Tip
Core tip: Our study of 27 patients who underwent hepatectomies focuses on early liver regeneration after resection in patients with hepatic tumors but no underlying liver disease and on determining if post-operative infective complications might influence it. We identify three predictive factors for optimal early regeneration.