Mewa Kinoo S, Maharaj K, Singh B, Govender M, Ramdial PK. Primary esophageal sclerosing mucoepidermoid carcinoma with “tissue eosinophilia”. World J Gastroenterol 2014; 20(22): 7055-7060 [PMID: 24944502 DOI: 10.3748/wjg.v20.i22.7055]
Corresponding Author of This Article
Bhugwan Singh, MD, Professor, Department of Surgery, Nelson R Mandela School of Medicine, University of Kwazulu-Natal, 719 Umbilo Road, Congella 4013, Durban 4013, South Africa. singhb3@ukzn.ac.za
Research Domain of This Article
Surgery
Article-Type of This Article
Case Report
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Suman Mewa Kinoo, Kapil Maharaj, Bhugwan Singh, Department of Surgery, Nelson R Mandela School of Medicine, University of Kwazulu Natal, Durban 4013, South Africa
Michelle Govender, Pratistadevi Kanaye Ramdial, Department of Anatomical Pathology, School of Laboratory Medicine and Medical Sciences, University of Kwazulu Natal and National Health Laboratory Service, Durban 4013, South Africa
Author contributions: All authors contributed equally to this work; The authors from the Department of Surgery provided the clinical features; The authors from the Department of Anatomical Pathology provided the pathological features; all authors contributed equally to the discussion and writing of the manuscript.
Correspondence to: Bhugwan Singh, MD, Professor, Department of Surgery, Nelson R Mandela School of Medicine, University of Kwazulu-Natal, 719 Umbilo Road, Congella 4013, Durban 4013, South Africa. singhb3@ukzn.ac.za
Telephone: +27-31-2604257 Fax: +27-31-2604389
Received: September 10, 2013 Revised: December 5, 2013 Accepted: January 6, 2014 Published online: June 14, 2014
Core Tip
Core tip: Primary mucoepidermoid cancer (MEC) of the esophagus, including the sclerosing variant, is rarely reported, and sclerosing MEC with “tissue eosinophilia” has never been reported in this location. The rarity of this latter condition has precluded a thorough understanding of esophageal MEC. Heightened recognition of MEC in this location is also necessary to distinguish MEC from squamous carcinoma, adenocarcinoma or adenosquamous carcinoma. This distinction has therapeutic implications. Based largely on past experience managing tumors in the salivary gland, MEC is characterized by a poor response to adjuvant chemotherapy and radiotherapy; notwithstanding a poor response to surgery, this treatment approach remains the mainstay of management.
