Published online Jun 14, 2014. doi: 10.3748/wjg.v20.i22.7040
Revised: January 10, 2014
Accepted: March 5, 2014
Published online: June 14, 2014
Core tip: Post-endoscopic retrograde cholangiopancreatography (ERCP) pancreatitis is the most common and serious complication of ERCP. In the past few decades, a number of clinical randomized controlled trials have shown that pancreatic stents can effectively prevent the occurrence of post-ERCP pancreatitis (PEP). In view of these high quality data, we conducted this meta-analysis to evaluate the effectiveness of pancreatic stent placement in preventing PEP in high-risk patients. Our results supported that pancreatic stent placement is an effective means to prevent PEP and alleviate the severity (mild and moderate) of PEP in high-risk patients. Furthermore, no serious complications were reported in subjects in the stent group.