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High Impact Articles
High impact papers are those to which special attention is paid by experts in the given field, with a large number of visitors, frequent downloads and higher citation rates. The research must be creative, with high academic standards and have a wide influence, if it is to become a high impact paper. They are ranked by the number of downloads.
Rank Full Article
Next-generation sequencing in clinical virology: Discovery of new viruses  
Sibnarayan Datta, Raghvendra Budhauliya, Bidisha Das, Soumya Chatterjee, Vanlalhmuaka, Vijay Veer 
World J Virology 4(3):265-276. Published online Aug 12, 2015. doi: 10.5501/wjv.v4.i3.265
Determination of 50% endpoint titer using a simple formula  
Muthannan Andavar Ramakrishnan 
World J Virol 5(2):85-86. Published online May 12, 2016. doi: 10.5501/wjv.v5.i2.85
Serological diagnosis of Epstein-Barr virus infection: Problems and solutions  
Massimo De Paschale, Pierangelo Clerici 
World J Virol 1(1):31-43. Published online Feb 12, 2012. doi: 10.5501/wjv.v1.i1.31
Architecture and biogenesis of plus-strand RNA virus replication factories  
David Paul, Ralf Bartenschlager 
World J Virol 2(2):32-48. Published online May 12, 2013. doi: 10.5501/wjv.v2.i2.32
Impact of antiretroviral therapy on lipid metabolism of human immunodeficiency virus-infected patients: Old and new drugs  
Joel da Cunha, Luciana Morganti Ferreira Maselli, Ana Carolina Bassi Stern, Celso Spada, Sérgio Paulo Bydlowski 
World J Virology 4(2):56-77. Published online May 12, 2015. doi: 10.5501/wjv.v4.i2.56
Update on hepatitis B and C virus diagnosis  
Livia Melo Villar, Helena Medina Cruz, Jakeline Ribeiro Barbosa, Cristianne Sousa Bezerra, Moyra Machado Portilho, Letícia de Paula Scalioni 
World J Virology 4(4):323-342. Published online Nov 12, 2015. doi: 10.5501/wjv.v4.i4.323
Post-transcriptional gene silencing, transcriptional gene silencing and human immunodeficiency virus  
Catalina Méndez, Chantelle L Ahlenstiel, Anthony D Kelleher 
World J Virology 4(3):219-244. Published online Aug 12, 2015. doi: 10.5501/wjv.v4.i3.219
West Nile virus: A re-emerging pathogen revisited  
Miguel A Martín-Acebes, Juan-Carlos Saiz 
World J Virol 1(2):51-70. Published online Apr 12, 2012. doi: 10.5501/wjv.v1.i2.51
Emerging and re-emerging viruses: A global challenge illustrated by Chikungunya virus outbreaks  
Christian A Devaux 
World J Virol 1(1):11-22. Published online Feb 12, 2012. doi: 10.5501/wjv.v1.i1.11
Nuclear domain 10 of the viral aspect  
Yisel A Rivera-Molina, Francisco Puerta Martínez, Qiyi Tang 
World J Virol 2(3):110-122. Published online Aug 12, 2013. doi: 10.5501/wjv.v2.i3.110
Pathogenicity of a currently circulating Chinese variant pseudorabies virus in pigs  
Qing-Yuan Yang, Zhe Sun, Fei-Fei Tan, Ling-Hua Guo, Yu-Zhou Wang, Juan Wang, Zhi-Yan Wang, Li-Lin Wang, Xiang-Dong Li, Yan Xiao, Ke-Gong Tian 
World J Virol 5(1):23-30. Published online Feb 12, 2016. doi: 10.5501/wjv.v5.i1.23
Genotyping and pathotyping of diversified strains of infectious bronchitis viruses circulating in Egypt  
Ali Zanaty, Abdel-Satar Arafa, Naglaa Hagag, Magdy El-Kady 
World J Virol 5(3):125-134. Published online Aug 12, 2016. doi: 10.5501/wjv.v5.i3.125
Microbiology laboratory and the management of mother-child varicella-zoster virus infection  
Massimo De Paschale, Pierangelo Clerici 
World J Virol 5(3):97-124. Published online Aug 12, 2016. doi: 10.5501/wjv.v5.i3.97
Value of routine dengue diagnosis in endemic countries  
James Ayukepi Ayukekbong, Olufunmilayo G Oyero, Samuel Ekpesu Nnukwu, Henry Nzike Mesumbe, Cajetang Nkong Fobisong 
World J Virol 6(1):9-16. Published online Feb 12, 2017. doi: 10.5501/wjv.v6.i1.9
Modelling the prevalence of hepatitis C virus amongst blood donors in Libya: An investigation of providing a preventive strategy  
Mohamed A Daw, Amira Shabash, Abdallah El-Bouzedi, Aghnya A Dau, Moktar Habas, Libyan Study Group of Hepatitis and HIV 
World J Virol 5(1):14-22. Published online Feb 12, 2016. doi: 10.5501/wjv.v5.i1.14
Real-world cure rates for hepatitis C virus treatments that include simeprevir and/or sofosbuvir are comparable to clinical trial results  
Kian Bichoupan, Neeta Tandon, James F Crismale, Joshua Hartman, David Del Bello, Neal Patel, Sweta Chekuri, Alyson Harty, Michel Ng, Keith M Sigel, Meena B Bansal, Priya Grewal, Charissa Y Chang, Jennifer Leong, Gene Y Im, Lawrence U Liu, Joseph A Odin, Nancy Bach, Scott L Friedman, Thomas D Schiano, Ponni V Perumalswami, Douglas T Dieterich, Andrea D Branch 
World J Virol 6(4):59-72. Published online Nov 12, 2017. doi: 10.5501/wjv.v6.i4.59
Neuropathology of JC virus infection in progressive multifocal leukoencephalopathy in remission  
Karen S SantaCruz, Gulmohor Roy, James Spigel, Elaine L Bearer 
World J Virol 5(1):31-37. Published online Feb 12, 2016. doi: 10.5501/wjv.v5.i1.31
Intrinsic host restriction factors of human cytomegalovirus replication and mechanisms of viral escape  
Santo Landolfo, Marco De Andrea, Valentina Dell’Oste, Francesca Gugliesi 
World J Virol 5(3):87-96. Published online Aug 12, 2016. doi: 10.5501/wjv.v5.i3.87
Geographic integration of hepatitis C virus: A global threat  
Mohamed A Daw, Abdallah A El-Bouzedi, Mohamed O Ahmed, Aghnyia A Dau, Mohamed M Agnan, Aisha M Drah 
World J Virol 5(4):170-182. Published online Nov 12, 2016. doi: 10.5501/wjv.v5.i4.170
Is transfusion-transmitted dengue fever a potential public health threat?  
Bruno Pozzetto, Meriam Memmi, Olivier Garraud 
World J Virology 4(2):113-123. Published online May 12, 2015. doi: 10.5501/wjv.v4.i2.113
Regulation of Wnt/β-catenin signaling by herpesviruses  
Kevin J Zwezdaryk, Joseph A Combs, Cindy A Morris, Deborah E Sullivan 
World J Virol 5(4):144-154. Published online Nov 12, 2016. doi: 10.5501/wjv.v5.i4.144
Current molecular methods for the detection of hepatitis C virus in high risk group population: A systematic review  
Rushna Firdaus, Kallol Saha, Aritra Biswas, Provash Chandra Sadhukhan 
World J Virology 4(1):25-32. Published online Feb 12, 2015. doi: 10.5501/wjv.v4.i1.25
Therapeutic and prevention strategies against human enterovirus 71 infection  
Chee Choy Kok 
World J Virology 4(2):78-95. Published online May 12, 2015. doi: 10.5501/wjv.v4.i2.78
Immunological-based assays for specific detection of shrimp viruses  
Parin Chaivisuthangkura, Siwaporn Longyant, Paisarn Sithigorngul 
World J Virol 3(1):1-10. Published online Feb 12, 2014. doi: 10.5501/wjv.v3.i1.1
Additional attention to combination antiretroviral therapy-related lipodystrophy  
Norihiko Kobayashi, Masako Nakahara, Masako Oka, Kumiko Saeki 
World J Virol 6(3):49-52. Published online Aug 12, 2017. doi: 10.5501/wjv.v6.i3.49
History of polio vaccination  
Anda Baicus 
World J Virol 1(4):108-114. Published online Aug 12, 2012. doi: 10.5501/wjv.v1.i4.108
Highly active antiretroviral therapy dysregulates proliferation and differentiation of human pre-adipocytes  
Eyone Jones, Pavel Mazirka, Margaret A McNurlan, Frank Darras, Marie C Gelato, Giuseppe Caso 
World J Virol 6(3):53-58. Published online Aug 12, 2017. doi: 10.5501/wjv.v6.i3.53
Hepatitis delta virus: A fascinating and neglected pathogen  
Celso Cunha, João Paulo Tavanez, Severin Gudima 
World J Virology 4(4):313-322. Published online Nov 12, 2015. doi: 10.5501/wjv.v4.i4.313
Molecular interactions between hepatitis B virus and delta virus  
Elham Shirvani-Dastgerdi, Frank Tacke 
World J Virology 4(2):36-41. Published online May 12, 2015. doi: 10.5501/wjv.v4.i2.36
What psychiatric screening and monitoring might be needed with the new generation of hepatitis C treatments?  
Paul J Rowan 
World J Virology 4(1):13-16. Published online Feb 12, 2015. doi: 10.5501/wjv.v4.i1.13
Structural and nucleic acid binding properties of hepatitis delta virus small antigen  
Carolina Alves, Hong Cheng, João Paulo Tavanez, Ana Casaca, Severin Gudima, Heinrich Roder, Celso Cunha 
World J Virol 6(2):26-35. Published online May 12, 2017. doi: 10.5501/wjv.v6.i2.26
Debunking the myths perpetuating low implementation of isoniazid preventive therapy amongst human immunodeficiency virus-infected persons  
Christopher Akolo, Florence Bada, Evaezi Okpokoro, Ogochukwu Nwanne, Sharon Iziduh, Eno Usoroh, Taofeekat Ali, Vivian Ibeziako, Olanrewaju Oladimeji, Michael Odo 
World J Virology 4(2):105-112. Published online May 12, 2015. doi: 10.5501/wjv.v4.i2.105
Rapid genotyping of human rotavirus using SYBR green real-time reverse transcription-polymerase chain reaction with melting curve analysis  
Yupin Tong, Bonita E Lee, Xiaoli L Pang 
World J Virology 4(4):365-371. Published online Nov 12, 2015. doi: 10.5501/wjv.v4.i4.365
Active tracking of rejected dried blood samples in a large program in Nigeria  
Auchi Inalegwu, Sunny Phillips, Rawlings Datir, Christopher Chime, Petronilla Ozumba, Samuel Peters, Obinna Ogbanufe, Charles Mensah, Alash’Le Abimiku, Patrick Dakum, Nicaise Ndembi 
World J Virol 5(2):73-81. Published online May 12, 2016. doi: 10.5501/wjv.v5.i2.73
Perinatally infected adolescents living with human immunodeficiency virus (perinatally human immunodeficiency virus)  
Maria Leticia S Cruz, Claudete A Cardoso 
World J Virology 4(3):277-284. Published online Aug 12, 2015. doi: 10.5501/wjv.v4.i3.277
Role of RNA secondary structure in emergence of compartment specific hepatitis B virus immune escape variants  
Sibnarayan Datta, Runu Chakravarty 
World J Virol 5(4):161-169. Published online Nov 12, 2016. doi: 10.5501/wjv.v5.i4.161
Matrix metalloproteases and their tissue inhibitors in non-alcoholic liver fibrosis of human immunodeficiency virus-infected patients  
Julio Collazos, Eulalia Valle-Garay, Tomás Suárez-Zarracina, Angel-Hugo Montes, José A Cartón, Víctor Asensi 
World J Virol 6(2):36-45. Published online May 12, 2017. doi: 10.5501/wjv.v6.i2.36
Prevalence of adenovirus and rotavirus infection in immunocompromised patients with acute gastroenteritis in Portugal  
Joana Ribeiro, Delfim Ferreira, Célia Arrabalde, Sandra Almeida, Inês Baldaque, Hugo Sousa 
World J Virology 4(4):372-376. Published online Nov 12, 2015. doi: 10.5501/wjv.v4.i4.372
Novel antigen delivery systems  
Maria Trovato, Piergiuseppe De Berardinis 
World J Virology 4(3):156-168. Published online Aug 12, 2015. doi: 10.5501/wjv.v4.i3.156
Twenty years of human immunodeficiency virus care at the Mayo Clinic: Past, present and future  
Nathan W Cummins, Andrew D Badley, Mary J Kasten, Rahul Sampath, Zelalem Temesgen, Jennifer A Whitaker, John W Wilson, Joseph D Yao, John Zeuli, Stacey A Rizza 
World J Virol 5(2):63-67. Published online May 12, 2016. doi: 10.5501/wjv.v5.i2.63
Paramyxovirus evasion of innate immunity: Diverse strategies for common targets  
Michelle D Audsley, Gregory W Moseley 
World J Virol 2(2):57-70. Published online May 12, 2013. doi: 10.5501/wjv.v2.i2.57
Innate host responses to West Nile virus: Implications for central nervous system immunopathology  
Giada Rossini, Maria Paola Landini, Francesco Gelsomino, Vittorio Sambri, Stefania Varani 
World J Virol 2(2):49-56. Published online May 12, 2013. doi: 10.5501/wjv.v2.i2.49
Antiretroviral naive and treated patients: Discrepancies of B cell subsets during the natural course of human immunodeficiency virus type 1 infection  
Olga Tsachouridou, Lemonia Skoura, Pantelis Zebekakis, Apostolia Margariti, Adamantini Georgiou, Dimitrios Bougiouklis, Dimitrios Pilalas, Antonios Galanos, Michael Daniilidis, Symeon Metallidis 
World J Virol 5(4):155-160. Published online Nov 12, 2016. doi: 10.5501/wjv.v5.i4.155
Viral hepatitis and human immunodeficiency virus co-infections in Asia  
Takako Utsumi, Maria I Lusida 
World J Virology 4(2):96-104. Published online May 12, 2015. doi: 10.5501/wjv.v4.i2.96
Diagnostic assays developed for the control of foot-and-mouth disease in India  
Gaurav Kumar Sharma, Sonalika Mahajan, Rakesh Matura, Saravanan Subramaniam, Rajeev Ranjan, Jitendra Biswal, Manoranjan Rout, Jajati Keshari Mohapatra, Bana Bihari Dash, Aniket Sanyal, Bramhadev Pattnaik 
World J Virology 4(3):295-302. Published online Aug 12, 2015. doi: 10.5501/wjv.v4.i3.295
Middle-East respiratory syndrome coronavirus: Is it worth a world panic?  
Ahmed S Abdel-Moneim 
World J Virology 4(3):185-187. Published online Aug 12, 2015. doi: 10.5501/wjv.v4.i3.185