Antiretroviral naive and treated patients: Discrepancies of B cell subsets during the natural course of human immunodeficiency virus type 1 infection
Olga Tsachouridou, Lemonia Skoura, Pantelis Zebekakis, Adamantini Georgiou, Dimitrios Pilalas, Antonios Galanos, Michael Daniilidis, Symeon Metallidis, 1st Internal Medicine Department, Infectious Diseases Division, Medical School, Aristotle University of Thessaloniki, 54636 Thessaloniki, Greece
Apostolia Margariti, Dimitrios Bougiouklis, National AIDS Reference Centre of Northern Greece, Medical School, Aristotle University of Thessaloniki, 54636 Thessaloniki, Greece
Author contributions: Tsachouridou O participated in recruiting patients, designing the study and in the writing of the manuscript; Skoura L, Zebekakis P and Daniilidis M contributed equally to this work and have designed, organized the study and edited the text and approved the final version of the manuscript; Margariti A, Bougiouklis D and Pilalas D contributed equally to this work and have processed the samples and executed the flow cytometry and extracted/interpreted the results and wrote part of the manuscript; Georgiou A and Galanos A contributed equally to this work and have performed the statistical analysis of the study, wrote part of the manuscipt and approved the final version of the article; Metallidis S participated in recruiting patients and drafting, writing and revised on the content of the manuscript; all authors have read and approved the final version of the article to be published.
Institutional review board statement: All blood samples from the patients were taken after informed consent and ethical permission was obtained for participation in the study.
Institutional animal care and use committee statement: No animal subjects were used in this study.
Conflict-of-interest statement: There are no conflicts of interest.
Data sharing statement: No additional data available.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Olga Tsachouridou, MD, PhD, Research Associate of Infectious Diseases Unit, 1st Internal Medicine Department, Infectious Diseases Division, Medical School, Aristotle University of Thessaloniki, 1 Stilponos Kyriakidi Street, 54636 Thessaloniki, Greece. firstname.lastname@example.org
Telephone: +30-2310-994656 Fax: +30-2310-993272
Received: April 22, 2016
Peer-review started: April 23, 2016
First decision: June 6, 2016
Revised: July 25, 2016
Accepted: August 17, 2016
Article in press: August 18, 2016
Published online: November 12, 2016