Copyright ©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Virology. May 12, 2015; 4(2): 113-123
Published online May 12, 2015. doi: 10.5501/wjv.v4.i2.113
Is transfusion-transmitted dengue fever a potential public health threat?
Bruno Pozzetto, Meriam Memmi, Olivier Garraud
Bruno Pozzetto, Meriam Memmi, Olivier Garraud, Groupe Immunité des Muqueuses et Agents Pathogènes (GIMAP EA3064), Faculty of Medicine Jacques Lisfranc, University of Lyon, 42023 Saint-Etienne cedex 02, France
Bruno Pozzetto, Laboratory of Infectious Agents and Hygiene, University-Hospital of Saint-Etienne, 42055 Saint-Etienne, France
Olivier Garraud, Institut National de la Transfusion Sanguine , 75011 Paris, France
Author contributions: Pozzetto B conceived the review and wrote the paper; Memmi M updated the bibliography, took care of the figures, contributed to the redaction of the manuscript and approved it; Garraud O improved substantially the content of the manuscript and approved it.
Conflict-of-interest: The authors declared no conflict of interest with regard to the subject of this article.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See:
Correspondence to: Bruno Pozzetto, MD, PhD, Professor of Medicine, Groupe Immunité des Muqueuses et Agents Pathogènes (GIMAP-EA 3064), Faculty of Medicine Jacques Lisfranc, University of Lyon, 15 rue Ambroise Paré, 42023 Saint-Etienne cedex 02, France.
Telephone: +33-4-77828434
Received: August 23, 2014
Peer-review started: August 24, 2014
First decision: September 16, 2014
Revised: October 29, 2014
Accepted: January 18, 2015
Article in press: Janurary 20, 2015
Published online: May 12, 2015
Core Tip

Core tip: The place of dengue viruses as transfusion-transmitted pathogens has been recognized only in 2008. By now, only five cases of transfusion-transmitted dengue, including one case of dengue haemorrhagic fever, have been formerly documented. This review provides a general overview of dengue, its viruses and their vectors. It replaces the disease in the context of other viral diseases transmitted by arthropods. It discusses the threat of dengue on the supply of blood products in endemic and non-endemic areas. Finally, it describes the specific and non-specific measures available for improving the security of blood products concerning this emerging risk.