Published online Aug 12, 2013. doi: 10.5501/wjv.v2.i3.110
Revised: May 31, 2013
Accepted: May 31, 2013
Published online: August 12, 2013
Core tip: We, for the first time, discussed the function of nuclear domain 10 (ND10) as a nuclear structure. Although the ND10 components, especially Promyelocytic Leukemia bodies, Speckled Protein of 100 kDa and death domain-associated protein, have been widely investigated for their roles in viral gene expression and viral replication, individual virus interacts with ND10 differentially as we summarized up in this review. This review is expected to guide readers especially virologists and cell biologists to understanding the interaction of ND10 with viruses.