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Open-Access Journal
Editorial
Cell therapy from bench to bedside: Hepatocytes from fibroblasts - the truth and myth of transdifferentiation 
Madhusudana Girija Sanal 
World J Gastroenterol 21(21):6427-6433. Published online Jun 7, 2015. doi: 10.3748/wjg.v21.i21.6427
Short-term and long-term risk factors in gastric cancer 
Giuseppe Verlato, Daniele Marrelli, Simone Accordini, Maria Bencivenga, Alberto Di Leo, Alberto Marchet, Roberto Petrioli, Giacomo Zoppini, Michele Muggeo, Franco Roviello, Giovanni de Manzoni 
World J Gastroenterol 21(21):6434-6443. Published online Jun 7, 2015. doi: 10.3748/wjg.v21.i21.6434
Controversy in the diagnosis of pediatric non-alcoholic fatty liver disease 
Pierluigi Marzuillo, Anna Grandone, Laura Perrone, Emanuele Miraglia del Giudice 
World J Gastroenterol 21(21):6444-6450. Published online Jun 7, 2015. doi: 10.3748/wjg.v21.i21.6444
Topic Highlight
Diagnostic and therapeutic applications of water-immersion colonoscopy 
Shinya Sugimoto, Takeshi Mizukami 
World J Gastroenterol 21(21):6451-6459. Published online Jun 7, 2015. doi: 10.3748/wjg.v21.i21.6451
Innovations and techniques for balloon-enteroscope-assisted endoscopic retrograde cholangiopancreatography in patients with altered gastrointestinal anatomy 
Hiroshi Yamauchi, Mitsuhiro Kida, Hiroshi Imaizumi, Kosuke Okuwaki, Shiro Miyazawa, Tomohisa Iwai, Wasaburo Koizumi 
World J Gastroenterol 21(21):6460-6469. Published online Jun 7, 2015. doi: 10.3748/wjg.v21.i21.6460
Different treatment strategies and molecular features between right-sided and left-sided colon cancers 
Hong Shen, Jiao Yang, Qing Huang, Meng-Jie Jiang, Yi-Nuo Tan, Jian-Fei Fu, Li-Zhen Zhu, Xue-Feng Fang, Ying Yuan 
World J Gastroenterol 21(21):6470-6478. Published online Jun 7, 2015. doi: 10.3748/wjg.v21.i21.6470
Review
Recent developments in pathogenesis, diagnosis and therapy of Barrett's esophagus 
Magnus Halland, David Katzka, Prasad G Iyer 
World J Gastroenterol 21(21):6479-6490. Published online Jun 7, 2015. doi: 10.3748/wjg.v21.i21.6479
Nocardia infections among immunomodulated inflammatory bowel disease patients: A review 
Cândida Abreu, Nuno Rocha-Pereira, António Sarmento, Fernando Magro 
World J Gastroenterol 21(21):6491-6498. Published online Jun 7, 2015. doi: 10.3748/wjg.v21.i21.6491
Role of dietary polyphenols in the management of peptic ulcer 
Mohammad Hosein Farzaei, Mohammad Abdollahi, Roja Rahimi 
World J Gastroenterol 21(21):6499-6517. Published online Jun 7, 2015. doi: 10.3748/wjg.v21.i21.6499
Minireviews
Transarterial radioembolization for hepatocellular carcinoma: An update and perspectives 
Rodolfo Sacco, Valeria Mismas, Sara Marceglia, Antonio Romano, Luca Giacomelli, Marco Bertini, Graziana Federici, Salvatore Metrangolo, Giuseppe Parisi, Emanuele Tumino, Giampaolo Bresci, Ambra Corti, Manuel Tredici, Michele Piccinno, Luigi Giorgi, Carlo Bartolozzi, Irene Bargellini 
World J Gastroenterol 21(21):6518-6525. Published online Jun 7, 2015. doi: 10.3748/wjg.v21.i21.6518
Basic Study
New NCI-N87-derived human gastric epithelial line after human telomerase catalytic subunit over-expression 
Kathy Saraiva-Pava, Nazanin Navabi, Emma C Skoog, Sara K Lindén, Mónica Oleastro, Mónica Roxo-Rosa 
World J Gastroenterol 21(21):6526-6542. Published online Jun 7, 2015. doi: 10.3748/wjg.v21.i21.6526
Low G preconditioning reduces liver injury induced by high +Gz exposure in rats 
Bin Shi, Zhi-Qiang Feng, Wen-Bing Li, Hong-Yi Zhang 
World J Gastroenterol 21(21):6543-6549. Published online Jun 7, 2015. doi: 10.3748/wjg.v21.i21.6543
Alternative splicing of VEGFA, APP and NUMB genes in colorectal cancer 
Yi-Jun Zhao, Hua-Zhong Han, Yong Liang, Chen-Zhang Shi, Qing-Chao Zhu, Jun Yang 
World J Gastroenterol 21(21):6550-6560. Published online Jun 7, 2015. doi: 10.3748/wjg.v21.i21.6550
Probiotic BIFICO cocktail ameliorates Helicobacter pylori induced gastritis 
Hong-Jing Yu, Wei Liu, Zhen Chang, Hui Shen, Li-Juan He, Sha-Sha Wang, Lu Liu, Yuan-Ying Jiang, Guo-Tong Xu, Mao-Mao An, Jun-Dong Zhang 
World J Gastroenterol 21(21):6561-6571. Published online Jun 7, 2015. doi: 10.3748/wjg.v21.i21.6561
Effect of resveratrol on Treg/Th17 signaling and ulcerative colitis treatment in mice 
Jun Yao, Cheng Wei, Jian-Yao Wang, Ru Zhang, Ying-Xue Li, Li-Sheng Wang 
World J Gastroenterol 21(21):6572-6581. Published online Jun 7, 2015. doi: 10.3748/wjg.v21.i21.6572
Transplantation of insulin-producing cells to treat diabetic rats after 90% pancreatectomy 
Ya-Bin Yu, Jian-Min Bian, Dian-Hua Gu 
World J Gastroenterol 21(21):6582-6590. Published online Jun 7, 2015. doi: 10.3748/wjg.v21.i21.6582
Loss of Dicer1 impairs hepatocyte survival and leads to chronic inflammation and progenitor cell activation 
Xu-Feng Lu, Yong-Jie Zhou, Lei Zhang, Hong-Jie Ji, Li Li, Yu-Jun Shi, Hong Bu 
World J Gastroenterol 21(21):6591-6603. Published online Jun 7, 2015. doi: 10.3748/wjg.v21.i21.6591
Case Control Study
Pancreatic cancer serum biomarker PC-594: Diagnostic performance and comparison to CA19-9 
Shawn A Ritchie, Bassirou Chitou, Qingan Zheng, Dushmanthi Jayasinghe, Wei Jin, Asuka Mochizuki, Dayan B Goodenowe 
World J Gastroenterol 21(21):6604-6612. Published online Jun 7, 2015. doi: 10.3748/wjg.v21.i21.6604
Retrospective Cohort Study
Growth and bone health in paediatric patients with Crohn's disease receiving subcutaneous tumor necrosis factor antibody 
Judith Pichler, Wolf Dietrich Huber, Christoph Aufricht, Bettina Bidmon-Fliegenschnee 
World J Gastroenterol 21(21):6613-6620. Published online Jun 7, 2015. doi: 10.3748/wjg.v21.i21.6613
Low RASSF6 expression in pancreatic ductal adenocarcinoma is associated with poor survival 
Hui-Lin Ye, Dou-Dou Li, Qing Lin, Yu Zhou, Quan-Bo Zhou, Bing Zeng, Zhi-Qiang Fu, Wen-Chao Gao, Yi-Min Liu, Rui-Wan Chen, Zhi-Hua Li, Ru-Fu Chen 
World J Gastroenterol 21(21):6621-6630. Published online Jun 7, 2015. doi: 10.3748/wjg.v21.i21.6621
Retrospective Study
High morbidity in myocardial infarction and heart failure patients after gastric cancer surgery 
Sang-Ho Jeong, Young-Woo Kim, Wansik Yu, Sang Ho Lee, Young Kyu Park, Seong-Heum Park, In Ho Jeong, Sang Eok Lee, Yongwhi Park, Young-Joon Lee 
World J Gastroenterol 21(21):6631-6638. Published online Jun 7, 2015. doi: 10.3748/wjg.v21.i21.6631
Precore/basal core promoter mutants quantification throughout phases of hepatitis B virus infection by Simpleprobe 
Wen-Hui Tu, Ying Lv, Yong-Mei Zhang, Wei Hou, Jin-Yu Wang, Yi-Jun Zhang, Hong-Yan Liu, Hao-Xiang Zhu, Yan-Li Qin, Ri-Cheng Mao, Ji-Ming Zhang 
World J Gastroenterol 21(21):6639-6648. Published online Jun 7, 2015. doi: 10.3748/wjg.v21.i21.6639
Neuron-glial antigen 2 overexpression in hepatocellular carcinoma predicts poor prognosis 
Le-Le Lu, Jing Sun, Jie-Juan Lai, Yan Jiang, Lian-Hua Bai, Lei-Da Zhang 
World J Gastroenterol 21(21):6649-6659. Published online Jun 7, 2015. doi: 10.3748/wjg.v21.i21.6649
Laparoscopic splenectomy for splenic littoral cell angioma 
Yun-Qiang Cai, Xing Wang, Xun Ran, Xu-Bao Liu, Bing Peng 
World J Gastroenterol 21(21):6660-6664. Published online Jun 7, 2015. doi: 10.3748/wjg.v21.i21.6660
Proportions of acetyl-histone-positive hepatocytes indicate the functional status and prognosis of cirrhotic patients 
Ping Zhou, Jie Xia, Yong-Jie Zhou, Jun Wan, Li Li, Ji Bao, Yu-Jun Shi, Hong Bu 
World J Gastroenterol 21(21):6665-6674. Published online Jun 7, 2015. doi: 10.3748/wjg.v21.i21.6665
Platelet to lymphocyte ratio as a novel prognostic tool for gallbladder carcinoma 
Qing Pang, Ling-Qiang Zhang, Rui-Tao Wang, Jian-Bin Bi, Jing-Yao Zhang, Kai Qu, Su-Shun Liu, Si-Dong Song, Xin-Sen Xu, Zhi-Xin Wang, Chang Liu 
World J Gastroenterol 21(21):6675-6683. Published online Jun 7, 2015. doi: 10.3748/wjg.v21.i21.6675
Hepatitis B virus genotypes and genome characteristics in China 
Hong-Mei Li, Jian-Qiong Wang, Rui Wang, Qian Zhao, Li Li, Jin-Ping Zhang, Tao Shen 
World J Gastroenterol 21(21):6684-6697. Published online Jun 7, 2015. doi: 10.3748/wjg.v21.i21.6684
Clinical Trials Study
Low efficacy of levofloxacin-doxycycline-based third-line triple therapy for Helicobacter pylori eradication in Italy 
Omero Alessandro Paoluzi, Giovanna Del Vecchio Blanco, Emanuela Visconti, Manuela Coppola, Carla Fontana, Marco Favaro, Francesco Pallone 
World J Gastroenterol 21(21):6698-6705. Published online Jun 7, 2015. doi: 10.3748/wjg.v21.i21.6698
Preliminary study of photodynamic diagnosis using 5-aminolevulinic acid in gastric and colorectal tumors 
Munetaka Nakamura, Jun Nishikawa, Kouichi Hamabe, Atsushi Goto, Junichi Nishimura, Hiroaki Shibata, Misato Nagao, Sho Sasaki, Shinichi Hashimoto, Takeshi Okamoto, Isao Sakaida 
World J Gastroenterol 21(21):6706-6712. Published online Jun 7, 2015. doi: 10.3748/wjg.v21.i21.6706
Observational Study
Associations of sense of coherence with psychological distress and quality of life in inflammatory bowel disease 
Thiago H Freitas, Elias Andreoulakis, Gilberto S Alves, Hesley LL Miranda, Lúcia LBC Braga, Thomas Hyphantis, André F Carvalho 
World J Gastroenterol 21(21):6713-6727. Published online Jun 7, 2015. doi: 10.3748/wjg.v21.i21.6713
Prospective Study
Burden of Clostridium difficile infection between 2010 and 2013: Trends and outcomes from an academic center in Eastern Europe 
Zsuzsanna Kurti, Barbara D Lovasz, Michael D Mandel, Zoltan Csima, Petra A Golovics, Bence D Csako, Anna Mohas, Lorant Gönczi, Krisztina B Gecse, Lajos S Kiss, Miklos Szathmari, Peter L Lakatos 
World J Gastroenterol 21(21):6728-6735. Published online Jun 7, 2015. doi: 10.3748/wjg.v21.i21.6728
3.0T 1H magnetic resonance spectroscopy for assessment of steatosis in patients with chronic hepatitis C 
Qian Zhang, Hui-Mao Zhang, Wen-Qian Qi, Yong-Gui Zhang, Ping Zhao, Jian Jiao, Jiang-Bin Wang, Chun-Yu Zhang 
World J Gastroenterol 21(21):6736-6744. Published online Jun 7, 2015. doi: 10.3748/wjg.v21.i21.6736
Systematic Reviews
Antioxidant drugs to prevent post-endoscopic retrograde cholangiopancreatography pancreatitis: What does evidence suggest? 
Clotilde Fuentes-Orozco, Carlos Dávalos-Cobián, Jesús García-Correa, Gabriela Ambriz-González, Michel Dassaejv Macías-Amezcua, Jesús García-Rentería, Jorge Rendón-Félix, Mariana Chávez-Tostado, Lizbeth Araceli Cuesta-Márquez, Andrea Socorro Alvarez-Villaseñor, Ana Olivia Cortés-Flores, Alejandro González-Ojeda 
World J Gastroenterol 21(21):6745-6753. Published online Jun 7, 2015. doi: 10.3748/wjg.v21.i21.6745
Case Report
True left-sided gallbladder with variations of bile duct and cholecystic vein 
Hiromichi Ishii, Akinori Noguchi, Mie Onishi, Koji Takao, Takahiro Maruyama, Hiroaki Taiyoh, Yasunobu Araki, Takeshi Shimizu, Hiroyuki Izumi, Naoki Tani, Masahide Yamaguchi, Tetsuro Yamane 
World J Gastroenterol 21(21):6754-6758. Published online Jun 7, 2015. doi: 10.3748/wjg.v21.i21.6754
Reactive lymphoid hyperplasia of the liver: Perinodular enhancement on contrast-enhanced computed tomography and magnetic resonance imaging 
Tetsuo Sonomura, Shinpei Anami, Taizo Takeuchi, Motoki Nakai, Shinya Sahara, Hirohiko Tanihata, Kazuki Sakamoto, Morio Sato 
World J Gastroenterol 21(21):6759-6763. Published online Jun 7, 2015. doi: 10.3748/wjg.v21.i21.6759
Testicular metastasis from gastric carcinoma: A case report 
Bo Li, Hui Cai, Zheng-Chun Kang, Hao Wu, Jian-Guo Hou, Li-Ye Ma 
World J Gastroenterol 21(21):6764-6768. Published online Jun 7, 2015. doi: 10.3748/wjg.v21.i21.6764