Retrospective Study
Copyright ©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Jun 7, 2015; 21(21): 6631-6638
Published online Jun 7, 2015. doi: 10.3748/wjg.v21.i21.6631
High morbidity in myocardial infarction and heart failure patients after gastric cancer surgery
Sang-Ho Jeong, Young-Woo Kim, Wansik Yu, Sang Ho Lee, Young Kyu Park, Seong-Heum Park, In Ho Jeong, Sang Eok Lee, Yongwhi Park, Young-Joon Lee
Sang-Ho Jeong, Young-Joon Lee, Department of Surgery, Gyengsang National University, Jinju 660-702, South Korea
Young-Woo Kim, Department of Surgery, Gastric Cancer Branch, National Cancer Center, Seoul 410-769, South Korea
Wansik Yu, Department of Surgery, Kyungpook National University Hospital, Daegu 700-721, South Korea
Sang Ho Lee, Deparment of Surgery, Kosin University College of Medicine, Pusan 602-702, South Korea
Young Kyu Park, Department of Surgery, Chonnam National University Hwasun Hospital, Hwasun 519-763, South Korea
Seong-Heum Park, Department of Surgery, South Korea University College of Medicine, South Korea University Ansan hospital, Ansan 425-707, South Korea
In Ho Jeong, Department of Surgery, Cheju National University, Cheju 690-767, South Korea
Sang Eok Lee, Department of Surgery, Konyang University Hospital, Daejeon 302-718, South Korea
Yongwhi Park, Department of Cardilolgy, Gyengsang National University, Jinju 660-702, South Korea
Author contributions: Jeong SH, Kim YW, Park Y and Lee YJ contributed to the concept and design of the review, analysis and interpretation of data, drafting of the manuscript; Kim YW, Yu W, Lee SH, Park YK, Park SH, Jeong IH and Lee SE contributed to analysis and interpretation of data and writing of the manuscript.
Ethics approval: The study was reviewed and approved by the The Institutional Review Board of Gyeongsang National University Hospital (GNUH 2015-1-005).
Informed consent: All study participants, or their legal guardian, provided informed written consent prior to study enrollment.
Conflict-of-interest: No potential conflics of interest relevant to this article was reported.
Data sharing: Technical appendix, statistical code, and dataset available from the corresponding author at yjleegnu@gmail.com. Participants gave informed consent for data sharing.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Young-Joon Lee, MD, Department of Surgery, Gyengsang National University, 90 Chilam-dong, Gyeongsang south province, Jinju 660-702, South Korea. yjleegnu@gmail.com
Telephone: +82-55-7508446 Fax: +82-55-7575442
Received: October 31, 2014
Peer-review started: November 3, 2014
First decision: November 26, 2014
Revised: February 3, 2015
Accepted: March 27, 2015
Article in press: March 27, 2015
Published online: June 7, 2015
Abstract

AIM: To evaluate to morbidity and mortality differences between 4 underlying heart diseases, myocardial infarction (MI), angina pectoris (Angina), heart failure (HF), and atrial fibrillation (AF), after radical surgery for gastric cancer.

METHODS: We retrospectively collected data from 221 patients of a total of 15167 patients who underwent radical gastrectomy and were preoperatively diagnosed with a history of Angina, MI, HF, or AF in 8 hospitals.

RESULTS: We find that the total morbidity rate is significantly higher in the MI group (44%) than the Angina (15.7%), AF (18.8%), and HF (23.1%) groups (P < 0.01). Moreover, we note that the risk for postoperative cardiac problems is higher in patients with a history of HF (23.1%) than patients with a history of Angina (2.2%), AF (4.3%), or MI (6%; P = 0.01). The HF and MI groups each have 1 case of cardiogenic mortality.

CONCLUSION: We conclude that MI patients have a higher risk of morbidity, and HF patients have a higher risk of postoperative cardiac problems than Angina or AF.

Keywords: Stomach neoplasm, Comorbidity, Morbidity, Heart disease, Heart failure

Core tip: The present study assessed morbidity and mortality differences among gastrectomy patients with underlying histories of myocardial infarction (MI), angina pectoris (Angina), heart failure (HF), and atrial fibrillation (AF). The authors concluded that gastric cancer patients with a history of MI had a higher risk for complications after gastrectomy, and patients with a history of HF had a higher risk for postoperative cardiac problems than patients with a history of Angina or AF. Therefore, patients with MI or HF require careful pre- and postoperative evaluation, and these patients should be informed about the possibility of postoperative morbidity, particularly intra-abdominal abscess and postoperative cardiac problems.