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©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Jun 7, 2015; 21(21): 6518-6525
Published online Jun 7, 2015. doi: 10.3748/wjg.v21.i21.6518
Published online Jun 7, 2015. doi: 10.3748/wjg.v21.i21.6518
Transarterial radioembolization for hepatocellular carcinoma: An update and perspectives
Rodolfo Sacco, Valeria Mismas, Antonio Romano, Luca Giacomelli, Marco Bertini, Graziana Federici, Salvatore Metrangolo, Giuseppe Parisi, Emanuele Tumino, Giampaolo Bresci, Ambra Corti, Department of Gastroenterology, Pisa University Hospital, 56124 Pisa, Italy
Sara Marceglia, Department of Electronics, Information technology and Bioengineering, Engineering School of Milan, 20100 Milan, Italy
Manuel Tredici, Department of Nuclear Medicine, Pisa University Hospital, 56124 Pisa, Italy
Michele Piccinno, Division of Health Physics, Pisa University Hospital, 56124 Pisa, Italy
Luigi Giorgi, Carlo Bartolozzi, Irene Bargellini, Department of Radiology, Pisa University Hospital, Pisa 56124, Italy
Author contributions: All the authors provided substantial contributions to conception of the manuscript; helped drafting the article or making critical revisions related to important intellectual content of the manuscript; and approved the final version of the article to be published.
Conflict-of-interest: The authors declare no conflict of interest.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Rodolfo Sacco, MD, PhD, Department of Gastroenterology, Pisa University Hospital, Via Paradisa 2, 56124 Pisa, Italy. r.sacco@ao-pisa.toscana.it
Telephone: +39-50-997411 Fax: +39-50-997412
Received: December 1, 2014
Peer-review started: December 1, 2014
First decision: January 22, 2015
Revised: March 13, 2015
Accepted: April 28, 2015
Article in press: April 28, 2015
Published online: June 7, 2015
Peer-review started: December 1, 2014
First decision: January 22, 2015
Revised: March 13, 2015
Accepted: April 28, 2015
Article in press: April 28, 2015
Published online: June 7, 2015
Core Tip
Core tip: This review provides an overview of trans-arterial radioembolization, a new therapeutic option for patients with hepatocellular carcinoma. In particular, the practical aspects of the technique and available data on disease control will be presented, with reference to patients in either early or advanced stages of disease, treated with trans-arterial embolization alone or within combination regimens.